Mutated Adenovirus Attacks in West Bengal, India: Risk Evaluation of Multi-Country Outbreaks and Mitigation Strategies.


Journal

Nursing open
ISSN: 2054-1058
Titre abrégé: Nurs Open
Pays: United States
ID NLM: 101675107

Informations de publication

Date de publication:
Oct 2024
Historique:
revised: 14 06 2024
received: 13 06 2023
accepted: 13 09 2024
medline: 21 10 2024
pubmed: 21 10 2024
entrez: 21 10 2024
Statut: ppublish

Résumé

The human adenovirus (HAdV) is beginning to spread rapidly in children through human, surface and animal vectors. Around 12,000 cases were recognised in 2022 in West Bengal and a shocking number of cases arose throughout India and in other under-developed areas. This is going to be a big threat to public health since no vaccine, awareness or protocol policies were introduced. Early detection, immediate isolation and proper policy developments are the key factors in overcoming the situation. Therefore, we performed this rapid review and discussed probable mitigation strategies, updated research on vaccine development, and treatment strategies to control the outbreaks of mutated HAdV. This is a narrative review of publicly available information. Here, we extracted updated information and data using the terms HAdV outbreaks, mutations, species, risks and prevention from Google Scholar and PubMed. We considered relevant articles that have discussed prevention strategies, ongoing research, and antiviral drugs for managing HAdV outbreaks. Early detection from throat swabs, isolation and symptomatic treatments are required to minimise viral infections. A massive test needs to be performed to find the affected people. The cases should be immediately isolated. It is recommended to treat high-touch surfaces with heat- or bleach-containing cleaners to prevent the spread of infection. Oxygen support and many broad-spectrum antivirals have been used to treat HAdV. Several studies showed antibody neutralisation and interactions between the natural killer cell receptor KIR3DS1 and HLA-F in infected cells, indicating possible therapeutic options in the future. HAdV-4 and HAdV-7 vaccines have been limitedly approved for administration to military personnel. Isolation, certain safety measures, broad-spectrum antiviral drugs and further research on new vaccines could be useful to prevent this virus from producing a worldwide pandemic. Also, the authorities should ensure the proper therapeutic interventions and nursing care facilities for the infected children. Patient or public contribution was not relevant to our work.

Identifiants

pubmed: 39428960
doi: 10.1002/nop2.70065
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

e70065

Informations de copyright

© 2024 The Author(s). Nursing Open published by John Wiley & Sons Ltd.

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Auteurs

Md Ashrafur Rahman (MA)

Nesbitt School of Pharmacy Wilkes University, Wilkes-Barre, Pennsylvania, USA.

Sydney Cronmiller (S)

Nesbitt School of Pharmacy Wilkes University, Wilkes-Barre, Pennsylvania, USA.

Julianne Ernest (J)

Nesbitt School of Pharmacy Wilkes University, Wilkes-Barre, Pennsylvania, USA.

Jonah Nguyen (J)

Nesbitt School of Pharmacy Wilkes University, Wilkes-Barre, Pennsylvania, USA.

Donovan Zong (D)

Nesbitt School of Pharmacy Wilkes University, Wilkes-Barre, Pennsylvania, USA.

Rob Davis (R)

Nesbitt School of Pharmacy Wilkes University, Wilkes-Barre, Pennsylvania, USA.

Amanda Rawa (A)

Nesbitt School of Pharmacy Wilkes University, Wilkes-Barre, Pennsylvania, USA.

Marie Roke Thomas (MR)

Nesbitt School of Pharmacy Wilkes University, Wilkes-Barre, Pennsylvania, USA.

Rana Al Mosharrafa (R)

Department of Business Administration, Faculty of Business Studies, Prime University, Dhaka, Bangladesh.

Yeasna Shanjana (Y)

Department of Environmental Sciences, North South University, Bashundhara, Dhaka, Bangladesh.

Md Rabiul Islam (MR)

School of Pharmacy, BRAC University, Dhaka, Bangladesh.

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