Visualization of membrane localization and the functional state of CB

Journal

Chemical science
ISSN: 2041-6520
Titre abrégé: Chem Sci
Pays: England
ID NLM: 101545951

Informations de publication

Date de publication:
03 Oct 2024
Historique:
received: 17 01 2024
accepted: 28 09 2024
medline: 21 10 2024
pubmed: 21 10 2024
entrez: 21 10 2024
Statut: aheadofprint

Résumé

The diversity of physiological roles of the endocannabinoid system has turned it into an attractive yet elusive therapeutic target. However, chemical probes with various functionalities could pave the way for a better understanding of the endocannabinoid system at the cellular level. Notably, inverse agonists of CB

Identifiants

DOI: 10.1039/d4sc00402g PMID: 39430942 PMC: PMC11485011
pubmed: 39430942
doi: 10.1039/d4sc00402g
pii: d4sc00402g
pmc: PMC11485011
doi:

Types de publication

Journal Article

Langues

eng

Informations de copyright

This journal is © The Royal Society of Chemistry.

Déclaration de conflit d'intérêts

The authors declare no competing financial interest.

Auteurs

M Wąsińska-Kałwa (M)

Leibniz-Forschungsinstitut für Molekulare Pharmakologie FMP Campus Berlin-Buch 13125 Berlin Germany nazare@fmp-berlin.de.

A Omran (A)

Leibniz-Forschungsinstitut für Molekulare Pharmakologie FMP Campus Berlin-Buch 13125 Berlin Germany nazare@fmp-berlin.de.

L Mach (L)

Leibniz-Forschungsinstitut für Molekulare Pharmakologie FMP Campus Berlin-Buch 13125 Berlin Germany nazare@fmp-berlin.de.

L Scipioni (L)

Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila 67100 L'Aquila Italy mauro.maccarrone@univaq.it.
European Center for Brain Research/Institute for Research and Health Care (IRCCS) Santa Lucia Foundation via del Fosso di Fiorano 64 00143 Rome Italy.
ORCID: 0000-0003-4764-8296

J Bouma (J)

Division of Drug Discovery and Safety, Leiden Academic Centre for Drug Research, Leiden University 2333 CC Leiden The Netherlands.

X Li (X)

iHuman Institute, ShanghaiTech University Shanghai 201210 China.
School of Life Science and Technology, ShanghaiTech University Shanghai 201210 China.

S Radetzki (S)

Leibniz-Forschungsinstitut für Molekulare Pharmakologie FMP Campus Berlin-Buch 13125 Berlin Germany nazare@fmp-berlin.de.

Y Mostinski (Y)

Leibniz-Forschungsinstitut für Molekulare Pharmakologie FMP Campus Berlin-Buch 13125 Berlin Germany nazare@fmp-berlin.de.

M Schippers (M)

Roche Pharma Research & Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd 4070 Basel Switzerland uwe.grether@roche.com.

T Gazzi (T)

Leibniz-Forschungsinstitut für Molekulare Pharmakologie FMP Campus Berlin-Buch 13125 Berlin Germany nazare@fmp-berlin.de.

C van der Horst (C)

Division of Drug Discovery and Safety, Leiden Academic Centre for Drug Research, Leiden University 2333 CC Leiden The Netherlands.

B Brennecke (B)

Leibniz-Forschungsinstitut für Molekulare Pharmakologie FMP Campus Berlin-Buch 13125 Berlin Germany nazare@fmp-berlin.de.

A Hanske (A)

Leibniz-Forschungsinstitut für Molekulare Pharmakologie FMP Campus Berlin-Buch 13125 Berlin Germany nazare@fmp-berlin.de.

Y Kolomeets (Y)

Leibniz-Forschungsinstitut für Molekulare Pharmakologie FMP Campus Berlin-Buch 13125 Berlin Germany nazare@fmp-berlin.de.

W Guba (W)

Roche Pharma Research & Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd 4070 Basel Switzerland uwe.grether@roche.com.

D Sykes (D)

Division of Physiology, Pharmacology & Neuroscience, School of Life Sciences, University of Nottingham Nottingham NG7 2UH UK.
Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham, University of Nottingham Midlands UK.

J P von Kries (JP)

Leibniz-Forschungsinstitut für Molekulare Pharmakologie FMP Campus Berlin-Buch 13125 Berlin Germany nazare@fmp-berlin.de.

J Broichhagen (J)

Leibniz-Forschungsinstitut für Molekulare Pharmakologie FMP Campus Berlin-Buch 13125 Berlin Germany nazare@fmp-berlin.de.
ORCID: 0000-0003-3084-6595

T Hua (T)

iHuman Institute, ShanghaiTech University Shanghai 201210 China.
School of Life Science and Technology, ShanghaiTech University Shanghai 201210 China.

D Veprintsev (D)

Division of Physiology, Pharmacology & Neuroscience, School of Life Sciences, University of Nottingham Nottingham NG7 2UH UK.
Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham, University of Nottingham Midlands UK.

L H Heitman (LH)

Division of Drug Discovery and Safety, Leiden Academic Centre for Drug Research, Leiden University 2333 CC Leiden The Netherlands.

S Oddi (S)

Department of Veterinary Medicine, University of Teramo Via R. Balzarini 1 64100 Teramo Italy soddi@unite.it.
European Center for Brain Research/Institute for Research and Health Care (IRCCS) Santa Lucia Foundation via del Fosso di Fiorano 64 00143 Rome Italy.
ORCID: 0000-0002-6217-698X

M Maccarrone (M)

Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila 67100 L'Aquila Italy mauro.maccarrone@univaq.it.
European Center for Brain Research/Institute for Research and Health Care (IRCCS) Santa Lucia Foundation via del Fosso di Fiorano 64 00143 Rome Italy.
ORCID: 0000-0002-3990-2963

U Grether (U)

Roche Pharma Research & Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd 4070 Basel Switzerland uwe.grether@roche.com.

M Nazare (M)

Leibniz-Forschungsinstitut für Molekulare Pharmakologie FMP Campus Berlin-Buch 13125 Berlin Germany nazare@fmp-berlin.de.
ORCID: 0000-0002-1602-2330

Classifications MeSH