Central artery pulse pressure, not central arterial stiffness impact on all-cause mortality in patients with viral pneumonia infection.
Arterial stiffness
Artificial intelligence
Blood pressure
Viral pneumonia
Journal
BMC infectious diseases
ISSN: 1471-2334
Titre abrégé: BMC Infect Dis
Pays: England
ID NLM: 100968551
Informations de publication
Date de publication:
21 Oct 2024
21 Oct 2024
Historique:
received:
06
07
2023
accepted:
16
10
2024
medline:
22
10
2024
pubmed:
22
10
2024
entrez:
21
10
2024
Statut:
epublish
Résumé
COVID-19 viral pneumonia can result in increased arterial stiffness, along with cardiac and systemic inflammatory responses. This study aimed to investigate the association between arterial stiffness, inflammation severity, and all-cause mortality in patients with COVID-19. In this study, anthropometric data, pneumonia infection severity, and blood tests were analyzed. Arterial stiffness was assessed using the non-invasive assessment indices, including arterial velocity pulse index (AVI) and central arterial pulse pressure (CAPP). Infection volumes and percentages for the whole lungs, most lobes, and most segments were extracted from CT images using artificial intelligence-based quantitative analysis software. The relationship between arterial stiffness, central hemodynamics, and all-cause mortality was investigated. In multivariable Cox regression analysis, high CAPP was significantly associated with all-cause mortality (hazard ratio: 0.263, 95% CI, 0.073-0.945, p = 0.041). Whole lung infection percentages were independently associated with high CAPP, with an area under the curve (AUC) of 0.662 and a specificity of 89.09%. High CAPP, but not high AVI, demonstrated independent prognostic value for all-cause mortality in patients due to COVID-19 pneumonia infection. Evaluating this parameter could help in risk assessment and improve diagnostic and therapeutic strategies in viral pneumonia infections.
Identifiants
pubmed: 39434023
doi: 10.1186/s12879-024-10091-y
pii: 10.1186/s12879-024-10091-y
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1183Subventions
Organisme : Natural Science Foundation of Shanghai
ID : 21ZR1451400
Organisme : Shanghai Jiading District Health and Family Planning Commission Fund
ID : 2021-KY-10
Organisme : Shanghai Health and Family Planning Commission Fund
ID : 202240235
Informations de copyright
© 2024. The Author(s).
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