Comprehensive neurosurgical and visceral surgical therapy of retroperitoneal nerve tumors: a descriptive and retrospective analysis.
Humans
Male
Female
Middle Aged
Retrospective Studies
Retroperitoneal Neoplasms
/ surgery
Adult
Neurilemmoma
/ surgery
Aged
Follow-Up Studies
Neurosurgical Procedures
/ methods
Prognosis
Neurofibroma
/ surgery
Young Adult
Neoplasm Recurrence, Local
/ surgery
Magnetic Resonance Imaging
/ methods
Retroperitoneal Space
/ surgery
BPNST
MPNST
Nerve
Peripheral
Retroperitoneum
Surgery
Tumor
Visceral
Journal
World journal of surgical oncology
ISSN: 1477-7819
Titre abrégé: World J Surg Oncol
Pays: England
ID NLM: 101170544
Informations de publication
Date de publication:
22 Oct 2024
22 Oct 2024
Historique:
received:
30
04
2024
accepted:
06
10
2024
medline:
22
10
2024
pubmed:
22
10
2024
entrez:
21
10
2024
Statut:
epublish
Résumé
Nerve tumors in the retroperitoneal space are a rarity. Radical surgery according to soft tissue tumors can lead to persistent pain and neurological deficits. This study aims to evaluate clinical outcomes of patients treated by a visceral- / neurosurgical approach. 33 patients with a retroperitoneal nerve tumor underwent surgery between 01/2002 and 12/2022 at our department. A visceral surgeon provided access to the retroperitoneal space, followed by micro-neurosurgical tumor preparation under neuromonitoring. Clinical examination and MRI were performed 12 weeks after surgery and further 3 months (WHO grade > 1) or 12 months (WHO grade 1). Further examinations were based on MRI findings and residual symptoms with median follow-up time of 24 months. One patient was treated for two distinct masses resulting in a total of 34 histological findings. Schwannomas (n = 15; 44.1%) and neurofibromas (n = 10; 29.4%) were the most common tumors. Long-term improvements were noted in radicular pain (15/18 patients; 83.3%), motor deficits (7/16 patients; 43.8%), abdominal discomfort and pain (5/7 patients; 71.4%). Recurrences were observed in 3/33 (9,1%) patients. This study represents the largest series of retroperitoneal BPNSTs treated with microsurgical techniques. Prospective multicenter studies are warranted to establish standardized treatment guidelines.
Identifiants
pubmed: 39434082
doi: 10.1186/s12957-024-03557-5
pii: 10.1186/s12957-024-03557-5
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
277Informations de copyright
© 2024. The Author(s).
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