3T-3D FLAIR MRI in Menière's disease: associated profiles with clinical symptoms and electroacoustic characteristics.
3D3T-MRI
Distortion-product otoacoustic emissions
Electrocochleography
Hydrops
Meniére’s disease
Journal
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
ISSN: 1434-4726
Titre abrégé: Eur Arch Otorhinolaryngol
Pays: Germany
ID NLM: 9002937
Informations de publication
Date de publication:
22 Oct 2024
22 Oct 2024
Historique:
received:
02
03
2024
accepted:
07
10
2024
medline:
23
10
2024
pubmed:
23
10
2024
entrez:
22
10
2024
Statut:
aheadofprint
Résumé
Diagnosis of Menière's disease relies on clinical symptoms. Injected 3T MRI can show endolymphatic hydrops (EH), but correlation with the clinical status of MD, (probable -PMD or definite-DMD) remains doubtful. We revealed endolymphatic pressure disruption through functional exploration and verified if it was associated with an EH through MRI. We prospectively analyzed 3D3T FLAIR MRI of DMD and PMD patients. All of them underwent electrocochleography (EcoG), distortion-product otoacoustic emissions (DPOAEs), and videonystagmograhy (VNG). Amplitudes of summating potential (SP) and cochlear nerve action potential (AP) were measured on EcoG. DPOAE-phase was collected at 1 kHz for the 2f1-f2 DPOAE between sitting and laying position. A SP/AP ≥ 40% and a DPOAE phase-shift > 40° revealed pressure disruption. 39 patients (25 women, 53 y.o. 20-78), were included, with 32 DMD ears and 11 PMD ears. MRI was performed in a median of 21 days [0; 68] from the MD incident. Audiovestibular exploration took place 41 days after the crisis [0;83]. MRI revealed an EH in 71.9% and 27.2% of DMD and PMD, respectively. When combining functional explorations and MRI, testing was positive in 97% for DMD and 82% for PMD. When abnormal (59%), VNG mainly showed hyporeflexia in the diseased ear. In patients suffering from DMD or PMD, with endolymphatic pressure disturbances confirmed by combined DPOAE-phase and EcoG, 3T 3D MRI reveals EH mostly in DMD but rarely in PMD. This seems to confirm that disturbance of endolymphatic pressure precedes EH.
Identifiants
pubmed: 39438294
doi: 10.1007/s00405-024-09029-6
pii: 10.1007/s00405-024-09029-6
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
© 2024. The Author(s).
Références
Bruderer SG, Bodmer D, Stohler NA et al (2017) Population-based study on the epidemiology of Ménière’s Disease. Audiol Neurootol 22:74–82. https://doi.org/10.1159/000475875
doi: 10.1159/000475875
pubmed: 28723686
Cureoglu S, da Costa Monsanto R, Paparella MM (2016) Histopathology of Meniere’s disease. Oper Tech Otolaryngol–Head Neck Surg 27:194–204. https://doi.org/10.1016/j.otot.2016.10.003
doi: 10.1016/j.otot.2016.10.003
Huang D, Chen P, Chen S et al (2002) Expression patterns of aquaporins in the inner ear: evidence for concerted actions of multiple types of aquaporins to facilitate water transport in the cochlea. Hear Res 165:85–95. https://doi.org/10.1016/s0378-5955(02)00288-5
doi: 10.1016/s0378-5955(02)00288-5
pubmed: 12031518
Mhatre AN, Jero J, Chiappini I et al (2002) Aquaporin-2 expression in the mammalian cochlea and investigation of its role in Meniere’s disease. Hear Res 170:59–69. https://doi.org/10.1016/s0378-5955(02)00452-5
doi: 10.1016/s0378-5955(02)00452-5
pubmed: 12208541
Nakashima T, Pyykkö I, Arroll MA et al (2016) Meniere’s disease. Nat Rev Dis Primer 2:16028. https://doi.org/10.1038/nrdp.2016.28
doi: 10.1038/nrdp.2016.28
Kim SH, Nam G-S, Choi JY (2019) Pathophysiologic findings in the human endolymphatic sac in endolymphatic Hydrops: functional and molecular evidence. Ann Otol Rhinol Laryngol 128:76S–83S. https://doi.org/10.1177/0003489419837993
doi: 10.1177/0003489419837993
pubmed: 31092029
Mom R, Robert-Paganin J, Mom T et al (2022) A Perspective for Ménière’s Disease: In Silico Investigations of Dexamethasone as a Direct Modulator of AQP2. Biomolecules 12:511. https://doi.org/10.3390/biom12040511
Pathak S, Vambutas A (2022) NaCl exposure results in increased expression and processing of IL-1β in Meniere’s disease patients. Sci Rep 12:4957. https://doi.org/10.1038/s41598-022-08967-7
doi: 10.1038/s41598-022-08967-7
pubmed: 35322136
pmcid: 8943007
Kumagami H, Loewenheim H, Beitz E et al (1998) The effect of anti-diuretic hormone on the endolymphatic sac of the inner ear. Pflugers Arch 436:970–975. https://doi.org/10.1007/s004240050731
doi: 10.1007/s004240050731
pubmed: 9799415
Gürkov R, Pyykö I, Zou J, Kentala E (2016) What is Menière’s disease? A contemporary re-evaluation of endolymphatic hydrops. J Neurol 263:71–81. https://doi.org/10.1007/s00415-015-7930-1
doi: 10.1007/s00415-015-7930-1
pmcid: 4833790
Lopez-Escamez JA, Carey J, Chung W-H et al (2015) Diagnostic criteria for Menière’s disease. J Vestib Res 25:1–7. https://doi.org/10.3233/VES-150549
doi: 10.3233/VES-150549
pubmed: 25882471
Gibson WP, Prasher DK, Kilkenny GP (1983) Diagnostic significance of transtympanic electrocochleography in Menière’s disease. Ann Otol Rhinol Laryngol 92:155–159. https://doi.org/10.1177/000348948309200212
doi: 10.1177/000348948309200212
pubmed: 6838105
Gerenton G, Giraudet F, Djennaoui I et al (2015) Abnormal fast fluctuations of electrocochleography and otoacoustic emissions in Menière’s disease. Hear Res 327:199–208. https://doi.org/10.1016/j.heares.2015.07.016
doi: 10.1016/j.heares.2015.07.016
pubmed: 26232527
Mom T, Gilain L, Avan P (2009) Effects of glycerol intake and body tilt on otoacoustic emissions reflect labyrinthine pressure changes in Menière’s disease. Hear Res 250:38–45. https://doi.org/10.1016/j.heares.2009.01.008
doi: 10.1016/j.heares.2009.01.008
pubmed: 19450433
Avan P, Giraudet F, Chauveau B et al (2011) Unstable distortion-product otoacoustic emission phase in Menière’s disease. Hear Res 277:88–95. https://doi.org/10.1016/j.heares.2011.03.006
doi: 10.1016/j.heares.2011.03.006
pubmed: 21426928
Franco-Vidal V, Legarlantezec C, Blanchet H et al (2005) Multifrequency admittancemetry in Ménière’s Disease: a preliminary study for a new diagnostic test. Otol Neurotol off Publ Am Otol Soc Am Neurotol Soc Eur Acad Otol Neurotol 26:723–727. https://doi.org/10.1097/01.mao.0000178136.81729.7c
doi: 10.1097/01.mao.0000178136.81729.7c
Gibson WP (2017) The clinical uses of Electrocochleography. Front Neurosci 11:274. https://doi.org/10.3389/fnins.2017.00274
doi: 10.3389/fnins.2017.00274
pubmed: 28634435
pmcid: 5437168
Hornibrook J (2017) Tone Burst Electrocochleography for the diagnosis of clinically certain Meniere’s Disease. Front Neurosci 11:301. https://doi.org/10.3389/fnins.2017.00301
doi: 10.3389/fnins.2017.00301
pubmed: 28670263
pmcid: 5472727
Mom T, Montalban A, Bascoul A et al (2012) Acoustic phase shift: objective evidence for intralabyrinthine pressure disturbance in Menière’s disease provided by otoacoustic emissions. Eur Ann Otorhinolaryngol Head Neck Dis 129:17–21. https://doi.org/10.1016/j.anorl.2011.07.004
doi: 10.1016/j.anorl.2011.07.004
pubmed: 22154207
Merchant SN, Adams JC, Nadol JB (2005) Pathophysiology of Meniere’s syndrome: are symptoms caused by endolymphatic hydrops? Otol Neurotol off Publ Am Otol Soc Am Neurotol Soc Eur. Acad Otol Neurotol 26:74–81. https://doi.org/10.1097/00129492-200501000-00013
doi: 10.1097/00129492-200501000-00013
Kato K, Yoshida T, Teranishi M et al (2012) Peak width in multifrequency tympanometry and endolymphatic hydrops revealed by magnetic resonance imaging. Otol Neurotol off Publ Am Otol Soc Am Neurotol Soc Eur Acad Otol Neurotol 33:912–915. https://doi.org/10.1097/MAO.0b013e31825d9a72
doi: 10.1097/MAO.0b013e31825d9a72
Juha-Pekka Vasama, Fred H, Linthicu (1999) Meniere’s Disease and endolymphatic Hydrops without Meniere’s symptoms: temporal bone histopathology. Acta Otolaryngol (Stockh) 119:297–301. https://doi.org/10.1080/00016489950181279
doi: 10.1080/00016489950181279
(1995) Committee on Hearing and Equilibrium guidelines for the diagnosis and evaluation of therapy in Menière’s disease. American Academy of Otolaryngology-Head and Neck Foundation, Inc. Otolaryngol–Head Neck Surg off J Am Acad Otolaryngol-Head Neck Surg 113:181–185. https://doi.org/10.1016/S0194-5998(95)70102-8
Kahn L, Hautefort C, Guichard J-P et al (2020) Relationship between video head impulse test, ocular and cervical vestibular evoked myogenic potentials, and compartmental magnetic resonance imaging classification in menière’s disease. Laryngoscope 130:E444–E452. https://doi.org/10.1002/lary.28362
doi: 10.1002/lary.28362
pubmed: 31742710
Connor S, Grzeda MT, Jamshidi B et al (2023) Delayed post gadolinium MRI descriptors for Meniere’s disease: a systematic review and meta-analysis. Eur Radiol. https://doi.org/10.1007/s00330-023-09651-8
doi: 10.1007/s00330-023-09651-8
pubmed: 37171493
pmcid: 10511628
Xiao H, Guo X, Cai H et al (2022) Magnetic resonance imaging of endolymphatic hydrops in Ménière’s disease: a comparison of the diagnostic value of multiple scoring methods. Front Neurol 13:967323. https://doi.org/10.3389/fneur.2022.967323
doi: 10.3389/fneur.2022.967323
pubmed: 36247770
pmcid: 9559191
Compagnone L, Levigne V, Pereira B et al (2022) Injected 3T-3D-FLAIR-MRI labyrinthine patterns match with the severity and tonotopic alteration in sudden sensorineural hearing loss. Eur Arch Oto-Rhino-Laryngol off J Eur Fed Oto-Rhino-Laryngol soc EUFOS Affil Ger soc Oto-Rhino-Laryngol -. Head Neck Surg 279:4883–4891. https://doi.org/10.1007/s00405-022-07328-4
doi: 10.1007/s00405-022-07328-4
Quatre R, Attyé A, Karkas A et al (2019) Relationship between Audio-vestibular functional tests and inner ear MRI in Meniere’s Disease. Ear Hear 40:168–176. https://doi.org/10.1097/AUD.0000000000000584
doi: 10.1097/AUD.0000000000000584
pubmed: 29698363
Yilmaz MS, Egilmez OK, Kara A, Guven M, Demir D, Genc Elden S (2021) Comparison of the results of caloric and video head impulse tests in patients with Meniere’s disease and vestibular migraine. Eur Arch Otorhinolaryngol 278(6):1829–1834 Epub 2020 Aug 9. PMID: 32772166
doi: 10.1007/s00405-020-06272-5
pubmed: 32772166
Lee SU, Kim HJ, Choi JY, Koo JW, Kim JS (2021) Evolution of caloric responses during and between the attacks of Meniere’s disease. J Neurol 268(8):2913–2921. https://doi.org/10.1007/s00415-021-10470-4 Epub 2021 Feb 21. PMID: 33611629
doi: 10.1007/s00415-021-10470-4
pubmed: 33611629
Mandegari M, Samiminia F, Baradaranfar M, Vaziribozorg S (2022) The efficacy of combined VHIT and VNG in the diagnosis of Vertigo caused by Meniere’s Disease. Indian J Otolaryngol Head Neck Surg 74(Suppl 3):4298–4305. https://doi.org/10.1007/s12070-021-02955-5 Epub 2021 Nov 2. PMID: 36742904; PMCID: PMC9895570
doi: 10.1007/s12070-021-02955-5
pubmed: 36742904
McCaslin DL, Rivas A, Jacobson GP, Bennett ML (2015) The dissociation of video head impulse test (vHIT) and bithermal caloric test results provide topological localization of vestibular system impairment in patients with definite Ménière’s disease. Am J Audiol. 24(1):1–10. https://doi.org/10.1044/2014_AJA-14-0040 . PMID: 25381440
Li J, Wang L, Hu N et al (2023) Improving diagnostic accuracy for probable and definite Ménière’s disease using magnetic resonance imaging. https://doi.org/10.1007/s00234-023-03176-z . Neuroradiology
Conlon BJ, Gibson WP (1999) Meniere’s disease: the incidence of hydrops in the contralateral asymptomatic ear. Laryngoscope 109:1800–1802. https://doi.org/10.1097/00005537-199911000-00014
doi: 10.1097/00005537-199911000-00014
pubmed: 10569410
House JW, Doherty JK, Fisher LM et al (2006) Meniere’s disease: prevalence of contralateral ear involvement. Otol Neurotol 27:355–361. https://doi.org/10.1097/00129492-200604000-00011
doi: 10.1097/00129492-200604000-00011
pubmed: 16639274
Kariya S, Cureoglu S, Fukushima H et al (2007) Histopathologic changes of contralateral human temporal bone in unilateral Ménière’s disease. Otol Neurotol off Publ Am Otol Soc Am Neurotol Soc Eur Acad Otol Neurotol 28:1063–1068. https://doi.org/10.1097/MAO.0b013e31815a8433
doi: 10.1097/MAO.0b013e31815a8433
Liu Y, Jia H, Shi J et al (2015) Endolymphatic hydrops detected by 3-dimensional fluid-attenuated inversion recovery MRI following intratympanic injection of gadolinium in the asymptomatic contralateral ears of patients with unilateral Ménière’s disease. Med Sci Monit Int Med J Exp Clin Res 21:701–707. https://doi.org/10.12659/MSM.892383
doi: 10.12659/MSM.892383
Lempert T, von Brevern M (2019) Vestibular migraine. Neurol Clin 37:695–706. https://doi.org/10.1016/j.ncl.2019.06.003
doi: 10.1016/j.ncl.2019.06.003
pubmed: 31563227
Dieterich M, Obermann M, Celebisoy N (2016) Vestibular migraine: the most frequent entity of episodic vertigo. J Neurol 263(Suppl 1):S82–89. https://doi.org/10.1007/s00415-015-7905-2
doi: 10.1007/s00415-015-7905-2
pubmed: 27083888
Oh S-Y, Dieterich M, Lee BN et al (2021) Endolymphatic Hydrops in patients with vestibular migraine and concurrent Meniere’s Disease. Front Neurol 12:594481. https://doi.org/10.3389/fneur.2021.594481
doi: 10.3389/fneur.2021.594481
pubmed: 33776877
pmcid: 7991602
Wu Q, Dai C, Zhao M, Sha Y (2016) The correlation between symptoms of definite Meniere’s disease and endolymphatic hydrops visualized by magnetic resonance imaging. Laryngoscope 126:974–979. https://doi.org/10.1002/lary.25576
doi: 10.1002/lary.25576
pubmed: 26333096
Zhang W, Hui L, Zhang B et al (2021) The correlation between endolymphatic Hydrops and clinical features of Meniere Disease. Laryngoscope 131:E144–E150. https://doi.org/10.1002/lary.28576
doi: 10.1002/lary.28576
pubmed: 32083730
Chen W, Wu X, Geng Y et al (2021) The clinical features and image characteristics of Meniere’s disease patients with endolymphatic hydrops confirmed by enhanced magnetic resonance imaging. Braz J Otorhinolaryngol S1808–8694(21):00159–00152. https://doi.org/10.1016/j.bjorl.2021.07.009
doi: 10.1016/j.bjorl.2021.07.009
Gürkov R, Flatz W, Louza J et al (2012) In vivo visualized endolymphatic hydrops and inner ear functions in patients with electrocochleographically confirmed Ménière’s disease. Otol Neurotol off Publ Am Otol Soc Am Neurotol Soc Eur Acad Otol Neurotol 33:1040–1045. https://doi.org/10.1097/MAO.0b013e31825d9a95
doi: 10.1097/MAO.0b013e31825d9a95