Investigation of CNS depressant and muscle relaxant effects of the ethnomedicinal plant

Background and objective

Since plant-based natural drugs are widely accepted in modern times and possess numerous pharmacological effects with an extensive therapeutic range, an ethnomedicinal plant native to Bangladesh was selected to investigate for investigation of its various pharmacological effects.

Methods

The CNS depressant activity was assessed using the hole cross, rota-rod, and elevated plus maze tests on Swiss Albino mice, while the antioxidant activity was evaluated using the 2,2-diphenyl-1-picrylhydrazyl free radical, hydrogen peroxide (H

Results

The conducted assays successfully demonstrated that the chloroform fraction of MDML is a significantly (

Conclusion

The presence of various phytochemicals might contribute to these activities. However, further research is suggested to isolate their active compounds and evaluate their mechanisms of action.

Informations de copyright

© 2024 Institute of Bioorganic Chemistry, Polish Academy of Sciences.

Déclaration de conflit d'intérêts

The authors declare that they have no conflict of interest.