Influence of sonic activation of epoxy-resin and calcium silicate sealer on postoperative pain: a patient-blinded, parallel group, randomized clinical trial.
Humans
Pain, Postoperative
/ prevention & control
Epoxy Resins
/ therapeutic use
Silicates
/ therapeutic use
Root Canal Filling Materials
/ therapeutic use
Male
Calcium Compounds
/ therapeutic use
Female
Adult
Pain Measurement
Periapical Periodontitis
/ surgery
Middle Aged
Root Canal Therapy
/ methods
Single-Blind Method
Calcium Phosphates
Drug Combinations
Oxides
Apical periodontitis
Calcium silicate
Endoactivator
Extrusion
Postoperative pain
Journal
BMC oral health
ISSN: 1472-6831
Titre abrégé: BMC Oral Health
Pays: England
ID NLM: 101088684
Informations de publication
Date de publication:
23 Oct 2024
23 Oct 2024
Historique:
received:
21
06
2024
accepted:
14
10
2024
medline:
24
10
2024
pubmed:
24
10
2024
entrez:
24
10
2024
Statut:
epublish
Résumé
This clinical study aims to compare postoperative pain after single-visit root canal treatment of teeth with asymptomatic apical periodontitis using epoxy-resin-based AH Plus and calcium silicate-based Endosequence BC sealers with or without sonic activation. This study included 72 individuals with one first or second mandibular premolar tooth with asymptomatic apical periodontitis. They were randomly divided into four groups according to the root canal sealer (AH Plus or Endosequence BC) and activation protocol (sonic activation or non-activation) (n = 18). The participants were ask to rate their postoperative pain intensity on a NRS scale as none, minimal, moderate, or severe after 24 h, 48 h, 72 h, and 7 days following treatment. Patients were also asked to record the number of prescribed analgesic medication tablets (400 mg of ibuprofen) taken. Statistical analysis were performed using the Mann-Whitney U test, the Friedman test, the Spearman's correlation test, the Chi-square test. Significance level was established at 0.05. There was no statistically significant difference in postoperative pain scores or analgesic intake between AH Plus and Endosequence BC sealers regardless of the activation protocol (p > 0.05). There was no statistically significant difference in postoperative pain scores between the sonic activation and non-activation groups (p > 0.05). A weak positive correlation was detected between Endoactivator sonic activation and sealer extrusion (r = 0.36). AH Plus and EndoSequence BC root canal sealers showed similar results in terms of prevalance and intensity of postoperative pain. Sonic activation and non-activation groups had similar postoperative pain scores. The study was retrospectively registered with ClinicalTrials.gov (NCT06403293). Date of Registration: 07/05/24.
Sections du résumé
BACKGROUND
BACKGROUND
This clinical study aims to compare postoperative pain after single-visit root canal treatment of teeth with asymptomatic apical periodontitis using epoxy-resin-based AH Plus and calcium silicate-based Endosequence BC sealers with or without sonic activation.
METHODS
METHODS
This study included 72 individuals with one first or second mandibular premolar tooth with asymptomatic apical periodontitis. They were randomly divided into four groups according to the root canal sealer (AH Plus or Endosequence BC) and activation protocol (sonic activation or non-activation) (n = 18). The participants were ask to rate their postoperative pain intensity on a NRS scale as none, minimal, moderate, or severe after 24 h, 48 h, 72 h, and 7 days following treatment. Patients were also asked to record the number of prescribed analgesic medication tablets (400 mg of ibuprofen) taken. Statistical analysis were performed using the Mann-Whitney U test, the Friedman test, the Spearman's correlation test, the Chi-square test. Significance level was established at 0.05.
RESULTS
RESULTS
There was no statistically significant difference in postoperative pain scores or analgesic intake between AH Plus and Endosequence BC sealers regardless of the activation protocol (p > 0.05). There was no statistically significant difference in postoperative pain scores between the sonic activation and non-activation groups (p > 0.05). A weak positive correlation was detected between Endoactivator sonic activation and sealer extrusion (r = 0.36).
CONCLUSIONS
CONCLUSIONS
AH Plus and EndoSequence BC root canal sealers showed similar results in terms of prevalance and intensity of postoperative pain. Sonic activation and non-activation groups had similar postoperative pain scores.
CLINICAL TRIAL REGISTRATION
BACKGROUND
The study was retrospectively registered with ClinicalTrials.gov (NCT06403293). Date of Registration: 07/05/24.
Identifiants
pubmed: 39443924
doi: 10.1186/s12903-024-05049-0
pii: 10.1186/s12903-024-05049-0
doi:
Substances chimiques
Epoxy Resins
0
Silicates
0
Root Canal Filling Materials
0
Calcium Compounds
0
calcium silicate
S4255P4G5M
epoxy resin-based root canal sealer
0
EndoSequence root repair material
0
Calcium Phosphates
0
Drug Combinations
0
Oxides
0
Banques de données
ClinicalTrials.gov
['NCT06403293']
Types de publication
Journal Article
Randomized Controlled Trial
Langues
eng
Sous-ensembles de citation
IM
Pagination
1268Informations de copyright
© 2024. The Author(s).
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