Interlaboratory comparison of endotoxin contamination assessment of nanomaterials.

Journal

Nanoscale
ISSN: 2040-3372
Titre abrégé: Nanoscale
Pays: England
ID NLM: 101525249

Informations de publication

Date de publication:
24 Oct 2024
Historique:
medline: 24 10 2024
pubmed: 24 10 2024
entrez: 24 10 2024
Statut: aheadofprint

Résumé

Endotoxin contamination is a significant hurdle to the translation of nanomaterials for biomedical applications. Multiple reports now describe that more than one-third of nanomaterials fail early pre-clinical assessment due to levels of endotoxin above regulatory requirements. Additionally, most immunological studies or

Identifiants

DOI: 10.1039/d4nr02821j PMID: 39445396
pubmed: 39445396
doi: 10.1039/d4nr02821j
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Auteurs

Gary Hannon (G)

Nanomedicine and Molecular Imaging Group, Department of Clinical Medicine, Trinity Translational Medicine Institute, Trinity College Dublin, Dublin, Ireland. prinamea@tcd.ie.
Laboratory of Biological Characterization of Advanced Materials (LBCAM), Trinity Translational Medicine Institute, Trinity College Dublin, Dublin, Ireland.
ORCID: 0000-0003-1204-0299

Bethany J Heaton (BJ)

Immunocompatibility Group, Department of Pharmacology and Therapeutics, Institute of Systems, Molecular, and Integrative Biology, University of Liverpool, Liverpool, UK.
Centre of Excellence for Long-Acting Therapeutics, Department of Pharmacology and Therapeutics, Institute of Systems, Molecular, and Integrative Biology, University of Liverpool, Liverpool, UK.
ORCID: 0000-0002-1495-1945

Alexander Plant-Hately (A)

Immunocompatibility Group, Department of Pharmacology and Therapeutics, Institute of Systems, Molecular, and Integrative Biology, University of Liverpool, Liverpool, UK.
Centre of Excellence for Long-Acting Therapeutics, Department of Pharmacology and Therapeutics, Institute of Systems, Molecular, and Integrative Biology, University of Liverpool, Liverpool, UK.
ORCID: 0000-0003-2425-1990

Christopher David (C)

Immunocompatibility Group, Department of Pharmacology and Therapeutics, Institute of Systems, Molecular, and Integrative Biology, University of Liverpool, Liverpool, UK.
Centre of Excellence for Long-Acting Therapeutics, Department of Pharmacology and Therapeutics, Institute of Systems, Molecular, and Integrative Biology, University of Liverpool, Liverpool, UK.
ORCID: 0000-0001-8504-2354

Neill J Liptrott (NJ)

Immunocompatibility Group, Department of Pharmacology and Therapeutics, Institute of Systems, Molecular, and Integrative Biology, University of Liverpool, Liverpool, UK.
Centre of Excellence for Long-Acting Therapeutics, Department of Pharmacology and Therapeutics, Institute of Systems, Molecular, and Integrative Biology, University of Liverpool, Liverpool, UK.
ORCID: 0000-0002-5980-8966

Ainhoa Egizabal (A)

TECNALIA, Basque Research and Technology Alliance (BRTA), Mikeletegi Pasealekua 2, 20009 Donostia-San Sebastián, Spain.
ORCID: 0000-0002-6266-0675

Ana Ayerdi-Izquierdo (A)

TECNALIA, Basque Research and Technology Alliance (BRTA), Mikeletegi Pasealekua 2, 20009 Donostia-San Sebastián, Spain.
ORCID: 0000-0002-5680-6340

Noelia Alvarez (N)

TECNALIA, Basque Research and Technology Alliance (BRTA), Mikeletegi Pasealekua 2, 20009 Donostia-San Sebastián, Spain.
ORCID: 0000-0002-2217-8702

Oihane Ibarrola (O)

Biokeralty Research Institute AIE, Parque Tecnológico de Álava, Vitoria- Gasteiz, Álava, Spain.
ORCID: 0000-0002-9089-6925

Andres Arbona Celaya (AA)

Biokeralty Research Institute AIE, Parque Tecnológico de Álava, Vitoria- Gasteiz, Álava, Spain.
ORCID: 0000-0002-8529-1868

Angel Del Pozo Perez (A)

Biokeralty Research Institute AIE, Parque Tecnológico de Álava, Vitoria- Gasteiz, Álava, Spain.

Nerea Lazcanoiturburu (N)

Biokeralty Research Institute AIE, Parque Tecnológico de Álava, Vitoria- Gasteiz, Álava, Spain.

Iris Luzuriagaf (I)

Biokeralty Research Institute AIE, Parque Tecnológico de Álava, Vitoria- Gasteiz, Álava, Spain.

Fikirte Debebe Zegeye (FD)

National Institute of Occupational Health, Oslo, Norway.
ORCID: 0000-0002-9501-9278

Shanbeh Zienolddiny-Narui (S)

National Institute of Occupational Health, Oslo, Norway.
ORCID: 0000-0001-9747-9625

An Jacobs (A)

Health department, Flemish Institute for Technological Research (VITO), Mol, Belgium.

Alexandra Van Driessche (A)

Health department, Flemish Institute for Technological Research (VITO), Mol, Belgium.
ORCID: 0000-0003-3536-9185

Inge Nelissen (I)

Health department, Flemish Institute for Technological Research (VITO), Mol, Belgium.
ORCID: 0000-0002-1248-3463

Ibane Abasolo (I)

Drug Delivery & Targeting, Vall d'Hebron Institute de Recerca (VHIR), Universitat Autònoma de Barcelona (UAB), 08035, Barcelona, Spain.
Networking Research Centre for Bioengineering, Biomaterials, and nanomedicine (CIBER-BBN), Instituto de Salud Carlos III, 28029, Madrid, Spain.
Functional Validation & Preclinical Research (FVPR)/U20 ICTS Nanobiosis, Vall d'Hebron Institut de Recerca (VHIR), Universitat Autònoma de Barcelona (UAB), 08035, Barcelona, Spain.
ORCID: 0000-0001-5970-6276

Fernanda Andrade (F)

Drug Delivery & Targeting, Vall d'Hebron Institute de Recerca (VHIR), Universitat Autònoma de Barcelona (UAB), 08035, Barcelona, Spain.
Networking Research Centre for Bioengineering, Biomaterials, and nanomedicine (CIBER-BBN), Instituto de Salud Carlos III, 28029, Madrid, Spain.
ORCID: 0000-0002-4947-2346

Nora Ventosa (N)

Networking Research Centre for Bioengineering, Biomaterials, and nanomedicine (CIBER-BBN), Instituto de Salud Carlos III, 28029, Madrid, Spain.
Institut de Ciència de Materials de Barcelona, ICMAB-CSIC, Campus UAB, 08193 Bellaterra, Spain.
ORCID: 0000-0002-8008-4974

Elisabet González-Mira (E)

Networking Research Centre for Bioengineering, Biomaterials, and nanomedicine (CIBER-BBN), Instituto de Salud Carlos III, 28029, Madrid, Spain.
Institut de Ciència de Materials de Barcelona, ICMAB-CSIC, Campus UAB, 08193 Bellaterra, Spain.
ORCID: 0000-0003-2502-225X

Aida Carreño (A)

Networking Research Centre for Bioengineering, Biomaterials, and nanomedicine (CIBER-BBN), Instituto de Salud Carlos III, 28029, Madrid, Spain.
Institut de Ciència de Materials de Barcelona, ICMAB-CSIC, Campus UAB, 08193 Bellaterra, Spain.
ORCID: 0000-0001-7725-7515

Adriele Prina-Mello (A)

Nanomedicine and Molecular Imaging Group, Department of Clinical Medicine, Trinity Translational Medicine Institute, Trinity College Dublin, Dublin, Ireland. prinamea@tcd.ie.
Laboratory of Biological Characterization of Advanced Materials (LBCAM), Trinity Translational Medicine Institute, Trinity College Dublin, Dublin, Ireland.
Advanced Materials and Bioengineering Research (AMBER) Centre, CRANN Institute, Trinity College Dublin, Dublin, Ireland.
ORCID: 0000-0002-4371-2214

Classifications MeSH