Distinct roles of two homologous kinesins in mammalian motile cilia.

Cilia / metabolism Kinesins / metabolism Animals Humans Cell Movement Mammals / metabolism

Journal

The Journal of cell biology
ISSN: 1540-8140
Titre abrégé: J Cell Biol
Pays: United States
ID NLM: 0375356

Informations de publication

Date de publication:
04 Nov 2024
Historique:
medline: 24 10 2024
pubmed: 24 10 2024
entrez: 24 10 2024
Statut: ppublish

Résumé

How do the two kinesin-9 members Kif6 and Kif9 function in mammalian cilia? Ou and colleagues discuss new work from Fang et al. (https://doi.org/10.1083/jcb.202312060) showing that Kif6 is an active motor while Kif9 serves as a stationary regulator, both of which are essential for cilia motility.

Identifiants

DOI: 10.1083/jcb.202409214 PMID: 39446171
pubmed: 39446171
pii: 277038
doi: 10.1083/jcb.202409214
pii:
doi:

Substances chimiques

Kinesins EC 3.6.4.4

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2024 Xu et al.

Auteurs

Kaiming Xu (K)

Tsinghua-Peking Center for Life Sciences, Beijing Frontier Research Center for Biological Structure, McGovern Institute for Brain Research, State Key Laboratory of Membrane Biology, School of Life Sciences and MOE Key Laboratory for Protein Science, Tsinghua University , Beijing, China.
ORCID: 0000-0001-5964-4490

Ming Li (M)

Tsinghua-Peking Center for Life Sciences, Beijing Frontier Research Center for Biological Structure, McGovern Institute for Brain Research, State Key Laboratory of Membrane Biology, School of Life Sciences and MOE Key Laboratory for Protein Science, Tsinghua University , Beijing, China.

Guangshuo Ou (G)

Tsinghua-Peking Center for Life Sciences, Beijing Frontier Research Center for Biological Structure, McGovern Institute for Brain Research, State Key Laboratory of Membrane Biology, School of Life Sciences and MOE Key Laboratory for Protein Science, Tsinghua University , Beijing, China.
ORCID: 0000-0003-1512-7824

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Classifications MeSH

questionsmedicales.fr › Cellules › Structures cellulaires › Prolongements cytoplasmiques › Cils vibratiles › Distinct roles of two homologous kinesins in...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines de tissu nerveux › Protéines associées aux microtubules › Kinésine › Distinct roles of two homologous kinesins in...
questionsmedicales.fr › Eucaryotes › Animaux › Distinct roles of two homologous kinesins in...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Distinct roles of two homologous kinesins in...
questionsmedicales.fr › Phénomènes physiologiques › Mouvement cellulaire › Distinct roles of two homologous kinesins in...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Distinct roles of two homologous kinesins in...