Venous Insufficiency: Wound Management.
Chronic venous hypertension
Venous insufficiency
Venous ulcer
Wound care
Journal
Current cardiology reports
ISSN: 1534-3170
Titre abrégé: Curr Cardiol Rep
Pays: United States
ID NLM: 100888969
Informations de publication
Date de publication:
24 Oct 2024
24 Oct 2024
Historique:
accepted:
15
09
2024
medline:
24
10
2024
pubmed:
24
10
2024
entrez:
24
10
2024
Statut:
aheadofprint
Résumé
Venous leg ulcers (VLUs) are one of the most common forms of chronic wounds and with nearly half the people having recurrent episodes, this significantly impacts a patient's quality of life. As such, VLU is a chronic disease that requires lifelong maintenance and awareness. A correct diagnosis of VLU is essential for management. VLUs can be of mixed etiology and treatment should be aimed at optimizing the underlying venous hypertension based on its cause. If there is an anatomical venous reflux contributing to the non-healing of the VLU, early treatment of incompetent veins can improve healing rates. All aspects contributing to the patient's ongoing venous hypertension should be addressed to provide appropriate treatment. This can include venous interventions but also through conservative measures. Patient education and their engagement in their own care is essential for good outcomes.
Identifiants
pubmed: 39446264
doi: 10.1007/s11886-024-02140-4
pii: 10.1007/s11886-024-02140-4
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
© 2024. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.
Références
Bergan JJ, Schmid-Schönbein GW, Smith PDC, Nicolaides AN, Boisseau MR, Eklof B. Chronic venous disease. N Engl J Med. 2006;355:488–98.
pubmed: 16885552
doi: 10.1056/NEJMra055289
Bergqvist D, Lindholm C, Nelzén O. Chronic leg ulcers: the impact of venous disease. J Vasc Surg. 1999;29:752–5.
pubmed: 10194512
doi: 10.1016/S0741-5214(99)70330-7
Salim S, Machin M, Patterson BO, Onida S, Davies AH. Global epidemiology of chronic venous disease: a systematic review with pooled prevalence analysis. Ann Surg. 2021;274:971.
pubmed: 33214466
doi: 10.1097/SLA.0000000000004631
O’Donnell TF, Passman MA, Marston WA, Ennis WJ, Dalsing M, Kistner RL, et al. Management of venous leg ulcers: clinical practice guidelines of the Society for Vascular Surgery
doi: 10.1016/j.jvs.2014.04.049
Alsaigh T, Fukaya E. Varicose veins and chronic venous disease. Cardiol Clin. 2021;39:567–81.
pubmed: 34686268
doi: 10.1016/j.ccl.2021.06.009
Kokkosis AA, Labropoulos N, Gasparis AP. Investigation of venous ulcers. Semin Vasc Surg. 2015;28:15–20.
pubmed: 26358305
doi: 10.1053/j.semvascsurg.2015.06.002
Maeseneer MGD, Kakkos SK, Aherne T, Baekgaard N, Black S, Blomgren L, et al. editors. ’s Choice – European Society for Vascular Surgery (ESVS) 2022 Clinical Practice Guidelines on the Management of Chronic Venous Disease of the Lower Limbs. European Journal of Vascular and Endovascular Surgery. 2022;63:184–267.
Coleridge-Smith P, Labropoulos N, Partsch H, Myers K, Nicolaides A, Cavezzi A, et al. Duplex ultrasound investigation of the veins in chronic venous disease of the lower limbs–UIP consensus document. Part I. Basic principles. Vasa. 2007;36:53–61.
pubmed: 17323300
doi: 10.1024/0301-1526.36.1.53
Labropoulos N, Tiongson J, Pryor L, Tassiopoulos AK, Kang SS, Mansour MA, et al. Definition of venous reflux in lower-extremity veins. J Vasc Surg. 2003;38:793–8.
pubmed: 14560232
doi: 10.1016/S0741-5214(03)00424-5
Klein A, Ennis W, Fukaya E. Characteristics of venous leg ulcer patients at a tertiary wound care center. J Vasc Surg Venous Lymphat Disord. 2023;11:270–e2791.
pubmed: 36410701
doi: 10.1016/j.jvsv.2022.09.018
Jayaraj A, Rossi FH, Lurie F, Muck P. Diagnosis of chronic iliac venous obstruction. Journal of Vascular Surgery: Venous and Lymphatic Disorders [Internet]. 2024 [cited 2024 Aug 12];12. https://www.jvsvenous.org/article/S2213-333X(23)00464-X/fulltext
Labropoulos N, Borge M, Pierce K, Pappas PJ. Criteria for defining significant central vein stenosis with duplex ultrasound. J Vasc Surg. 2007;46:101–7.
pubmed: 17540535
doi: 10.1016/j.jvs.2007.02.062
Gagne PJ, Tahara RW, Fastabend CP, Dzieciuchowicz L, Marston W, Vedantham S, et al. Venography versus intravascular ultrasound for diagnosing and treating iliofemoral vein obstruction. J Vasc Surg Venous Lymphat Disord. 2017;5:678–87.
pubmed: 28818221
doi: 10.1016/j.jvsv.2017.04.007
Montminy ML, Thomasson JD, Tanaka GJ, Lamanilao LM, Crim W, Raju S. A comparison between intravascular ultrasound and venography in identifying key parameters essential for iliac vein stenting. J Vasc Surg Venous Lymphat Disord. 2019;7:801–7.
pubmed: 31196766
doi: 10.1016/j.jvsv.2019.03.015
Körber A, Klode J, Al-Benna S, Wax C, Schadendorf D, Steinstraesser L, et al. Etiology of chronic leg ulcers in 31,619 patients in Germany analyzed by an expert survey. J Dtsch Dermatol Ges. 2011;9:116–21.
pubmed: 20946240
Nickles MA, Ennis WJ, O’Donnell TF, Altman IA. Compression therapy in peripheral artery disease: a literature review. J Wound Care. 2023;32:S25–30.
pubmed: 37121666
doi: 10.12968/jowc.2023.32.Sup5.S25
Kanth AM, Khan SU, Gasparis A, Labropoulos N. The distribution and extent of reflux and obstruction in patients with active venous ulceration. Phlebology. 2015;30:350–6.
pubmed: 24681524
doi: 10.1177/0268355514530277
Lawrence PF, Hager ES, Harlander-Locke MP, Pace N, Jayaraj A, Yohann A, et al. Treatment of superficial and perforator reflux and deep venous stenosis improves healing of chronic venous leg ulcers. J Vascular Surgery: Venous Lymphatic Disorders. 2020;8:601–9.
pubmed: 32089497
Gohel MS, Mora MSc J, Szigeti M, Epstein DM, Heatley F, Bradbury A, et al. Long-term clinical and cost-effectiveness of early endovenous ablation in venous ulceration: a Randomized Clinical Trial. JAMA Surg. 2020;155:1113–21.
pubmed: 32965493
pmcid: 7512122
doi: 10.1001/jamasurg.2020.3845
Marston WA. Efficacy of endovenous ablation of the saphenous veins for prevention and healing of venous ulcers. J Vascular Surgery: Venous Lymphatic Disorders. 2015;3:113–6.
pubmed: 26993692
Gohel MS, Heatley F, Liu X, Bradbury A, Bulbulia R, Cullum N, et al. A randomized trial of early endovenous ablation in venous Ulceration. N Engl J Med. 2018;378:2105–14.
pubmed: 29688123
doi: 10.1056/NEJMoa1801214
Kiernan A, Fahey B, Boland F, Aherne T. A systematic review and meta-analysis of concomitant truncal and perforator surgery. J Vasc Surg Venous Lymphat Disord. 2023;11:648–e6563.
pubmed: 36736858
doi: 10.1016/j.jvsv.2022.12.068
Abdul-Haqq R, Almaroof B, Chen BL, Panneton JM, Parent FN. Endovenous laser ablation of great saphenous vein and perforator veins improves venous stasis ulcer healing. Ann Vasc Surg. 2013;27:932–9.
pubmed: 23711972
doi: 10.1016/j.avsg.2012.09.014
Alhalbouni S, Hingorani A, Shiferson A, Gopal K, Jung D, Novak D, et al. Iliac-femoral venous stenting for lower extremity venous stasis symptoms. Ann Vasc Surg. 2012;26:185–9.
pubmed: 22018502
doi: 10.1016/j.avsg.2011.05.033
Gloviczki P, Lawrence PF, Wasan SM, Meissner MH, Almeida J, Brown KR, et al. The 2023 society for vascular surgery, American venous forum, and American Vein and Lymphatic Society clinical practice guidelines for the management of varicose veins of the lower extremities. Part II: endorsed by the Society of Interventional Radiology and the Society for Vascular Medicine. J Vasc Surg Venous Lymphat Disord. 2024;12:101670.
pubmed: 37652254
doi: 10.1016/j.jvsv.2023.08.011
Gloviczki P, Lawrence PF, Wasan SM, Meissner MH, Almeida J, Brown KR, et al. The 2022 society for vascular surgery, American venous forum, and American Vein and Lymphatic Society clinical practice guidelines for the management of varicose veins of the lower extremities. Part I. duplex scanning and treatment of superficial truncal reflux: endorsed by the Society for Vascular Medicine and the International Union of Phlebology. J Vasc Surg Venous Lymphat Disord. 2023;11:231–e2616.
pubmed: 36326210
doi: 10.1016/j.jvsv.2022.09.004
Shrestha O, Basukala S, Thapa N, Karki S, Pant P, Paudel S. Endovenous laser ablation versus conventional surgery (ligation and stripping) for primary great saphenous varicose vein: a systematic review and meta-analysis. Ann Med Surg (Lond). 2023;85:4509–19.
pubmed: 37663729
doi: 10.1097/MS9.0000000000001095
Kheirelseid EAH, Crowe G, Sehgal R, Liakopoulos D, Bela H, Mulkern E, et al. Systematic review and meta-analysis of randomized controlled trials evaluating long-term outcomes of endovenous management of lower extremity varicose veins. J Vasc Surg Venous Lymphat Disord. 2018;6:256–70.
pubmed: 29292115
doi: 10.1016/j.jvsv.2017.10.012
Kamhawy AH, Elbarbary AH, Elhenidy MA, Elwagih AMM. Periulcer Foam Sclerotherapy Injection in chronic venous Leg Ulcers using Near-Infrared laser for vein visualization. Int J Low Extrem Wounds. 2020;19:63–9.
pubmed: 31496316
doi: 10.1177/1534734619870680
Reitz KM, Salem K, Mohapatra A, Liang NL, Avgerinos ED, Singh MJ, et al. Complete venous Ulceration Healing after Perforator ablation does not depend on treatment modality. Ann Vasc Surg. 2021;70:109–15.
pubmed: 32603845
doi: 10.1016/j.avsg.2020.06.051
Siribumrungwong B, Wilasrusmee C, Orrapin S, Srikuea K, Benyakorn T, McKay G, et al. Interventions for great saphenous vein reflux: network meta-analysis of randomized clinical trials. Br J Surg. 2021;108:244–55.
pubmed: 33793723
pmcid: 10364879
doi: 10.1093/bjs/znaa101
Rasmussen L, Lawaetz M, Serup J, Bjoern L, Vennits B, Blemings A, et al. Randomized clinical trial comparing endovenous laser ablation, radiofrequency ablation, foam sclerotherapy, and surgical stripping for great saphenous varicose veins with 3-year follow-up. J Vasc Surg Venous Lymphat Disord. 2013;1:349–56.
pubmed: 26992754
doi: 10.1016/j.jvsv.2013.04.008
Obermayer A, Aubry J-F, Barnat N. Extracorporeal treatment with high intensity focused Ultrasound of an incompetent perforating vein in a patient with active venous ulcers. EJVES Vascular Forum. 2021;50:1–5.
pubmed: 33377135
doi: 10.1016/j.ejvsvf.2020.11.005
Obermayer A, Steinbacher F. First experience with Sonovein HD. J Vascular Surgery: Venous Lymphatic Disorders. 2023;11:466.
Joh M, Desai KR. Interventional Radiology in nonthrombotic venous interventions: treatment of nonthrombotic iliac vein lesions. Semin Interv Radiol. 2021;38:155.
doi: 10.1055/s-0041-1727101
Jayaraj A, Powell T, Raju S. Utility of the 50% stenosis criterion for patients undergoing stenting for chronic iliofemoral venous obstruction. J Vascular Surgery: Venous Lymphatic Disorders. 2021;9:1408–15.
pubmed: 34098125
Lurie F, Branisteanu DE. Improving chronic venous Disease Management with Micronised purified Flavonoid Fraction: New evidence from clinical trials to Real Life. Clin Drug Investig. 2023;43:9–13.
pubmed: 37171748
pmcid: 10220107
doi: 10.1007/s40261-023-01261-y
Sun S-Y, Li Y, Gao Y-Y, Ran X-W. Efficacy and safety of Pentoxifylline for venous Leg Ulcers: an updated Meta-analysis. Int J Low Extrem Wounds. 2024;23:264–74.
pubmed: 34779680
doi: 10.1177/15347346211050769
Jull AB, Arroll B, Parag V, Waters J. Pentoxifylline for treating venous leg ulcers. Cochrane Database of Systematic Reviews [Internet]. 2012 [cited 2024 Aug 5]; https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD001733.pub3/full
Bouskela E, Lugli M, Nicolaides A. New perspectives on Micronised purified Flavonoid Fraction in chronic venous disease: from Microvalves to Clinical Effectiveness. Adv Ther. 2022;39:4413–22.
pubmed: 35951224
pmcid: 9464747
doi: 10.1007/s12325-022-02218-x
Pompilio G, Nicolaides A, Kakkos SK, Integlia D. Systematic literature review and network Meta-analysis of sulodexide and other drugs in chronic venous disease. Phlebology. 2021;36:695–709.
pubmed: 33983078
doi: 10.1177/02683555211015020
Ruiz MJS, Moll NV, Gálvez MM, Jiménez MG, Muñoz LA. Compression therapy in patients with venous leg ulcers: a best practice implementation project. JBI Evid Implement. 2024.
Raffetto JD, Ligi D, Maniscalco R, Khalil RA, Mannello F. Why venous Leg Ulcers have Difficulty Healing: overview on pathophysiology, clinical consequences, and treatment. J Clin Med. 2020;10:29.
pubmed: 33374372
pmcid: 7795034
doi: 10.3390/jcm10010029
Dabiri G, Hammerman S, Carson P, Falanga V. Low-grade elastic compression regimen for venous leg ulcers–an effective compromise for patients requiring daily dressing changes. Int Wound J. 2015;12:655–61.
pubmed: 24267477
doi: 10.1111/iwj.12186
O’Meara S, Cullum N, Nelson EA, Dumville JC. Compression for venous leg ulcers. Cochrane Database Syst Rev. 2012;11:CD000265.
pubmed: 23152202
Nelson EA, Hillman A, Thomas K. Intermittent pneumatic compression for treating venous leg ulcers. Cochrane Database Syst Rev. 2014;2014:CD001899.
pubmed: 24820100
pmcid: 10788769
Blumberg SN, Maggi J, Melamed J, Golinko M, Ross F, Chen W. A histopathologic basis for surgical debridement to promote healing of venous ulcers. J Am Coll Surg. 2012;215:751–7.
pubmed: 22981433
doi: 10.1016/j.jamcollsurg.2012.08.008
Cardinal M, Eisenbud DE, Armstrong DG, Zelen C, Driver V, Attinger C, et al. Serial surgical debridement: a retrospective study on clinical outcomes in chronic lower extremity wounds. Wound Repair Regen. 2009;17:306–11.
pubmed: 19660037
doi: 10.1111/j.1524-475X.2009.00485.x
Coelho GA, Secretan P-H, Tortolano L, Charvet L, Yagoubi N. Evolution of the chronic venous Leg Ulcer Microenvironment and its impact on Medical devices and Wound Care therapies. J Clin Med. 2023;12:5605.
pubmed: 37685674
pmcid: 10488485
doi: 10.3390/jcm12175605
Norman G, Westby MJ, Rithalia AD, Stubbs N, Soares MO, Dumville JC. Dressings and topical agents for treating venous leg ulcers. Cochrane Database Syst Rev. 2018;6:CD012583.
pubmed: 29906322
Bruwer FA, Botma Y, Mulder M. Evidence-based practice regarding lower leg ulcers: a mapping review. Wound Healing South Afr. 2023;16:35–41.
Eberhardt RT, Raffetto JD. Chronic Venous Insufficiency Circulation. 2014;130:333–46.
pubmed: 25047584
Shah JB, Sheffield PJ, Fife CE. Textbook of Chronic Wound Care [Internet]. Best Publishing Company; 2018. https://books.google.com/books?id=byC1EAAAQBAJ
Poß-Doering R, Anders C, Fleischhauer T, Szecsenyi J, Senft JD. Exploring healthcare provider and patient perspectives on current outpatient care of venous leg ulcers and potential interventions to improve their treatment: a mixed methods study in the ulcus cruris care project. BMC Prim Care. 2022;23:229.
pubmed: 36076159
pmcid: 9453712
doi: 10.1186/s12875-022-01841-5
Ghaly P, Iliopoulos J, Ahmad M. The role of nutrition in wound healing: an overview. Br J Nurs. 2021;30:S38–42.
pubmed: 33733851
doi: 10.12968/bjon.2021.30.5.S38
Jiménez-García JF, Aguilera-Manrique G, Arboledas-Bellón J, Gutiérrez-García M, González-Jiménez F, Lafuente-Robles N, et al. The effectiveness of Advanced Practice nurses with respect to Complex Chronic wounds in the management of venous ulcers. Int J Environ Res Public Health. 2019;16:5037.
pubmed: 31835653
pmcid: 6950269
doi: 10.3390/ijerph16245037