Moderators of outcome in self-guided internet-delivered cognitive-behavior therapy for obsessive-compulsive disorder.

Internet-delivered cognitive behavioural therapy (ICBT) is an effective treatment for obsessive-compulsive disorder (OCD). Currently there is limited research examining the predictors and moderators of outcome in ICBT for OCD. This study examined moderators of treatment outcome in a sample of 216 individuals who commenced a self-guided ICBT intervention for OCD (Mage = 34.00; SD = 12.57; 72.7% female). The results indicated that those with higher baseline OCD severity, depression severity, and neuroticism had less improvement at post-treatment and follow up (resulting in 40%, 24% and 12% higher symptom severity for every standard deviation increase on the measure at post-treatment and 33%, 17% and 20% higher symptoms at follow up respectively). However, participants with higher baseline treatment expectancy and readiness to reduce rituals and compulsions had better outcomes at post-treatment and three-month follow up (resulting in a 5% and 7% lower symptom severity for every standard deviation increase on the measure at post-treatment and 12% and 12% lower symptoms at follow up respectively). The results have important implications for who may respond best to self-guided ICBT.

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Déclaration de conflit d'intérêts

Declaration of competing interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Bethany Wootton reports financial support was provided by International OCD Foundation. - The International OCD Foundation funded the study through an Innovation Award that was awarded to Bethany Wootton, Blake Dear, Nick Titov and Eyal Karin. - Blake Dear is a member of the Editorial Board for Behaviour Research and Therapy - The intervention used in the study was developed by Bethany Wootton, Blake Dear, and Nick Titov, however we do not receive any financial payment from participants. - The special issue guest editor (Maddy Bisby) is an employee of co-author Blake Dear. If there are other authors, they declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.