The ASAP study: association of atherosclerosis with pathobiology in a caucasian cohort-a study of 3400 autopsy reports.
Age
Atherosclerosis
Autopsy study
Body mass index
Epidemiology
Sex
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
24 Oct 2024
24 Oct 2024
Historique:
received:
22
05
2024
accepted:
16
10
2024
medline:
25
10
2024
pubmed:
25
10
2024
entrez:
25
10
2024
Statut:
epublish
Résumé
Cardiovascular plaques result from atherosclerosis. Autopsy investigations of unnatural deaths provide atherosclerosis research. A Central European cohort was studied in a cross-sectional study to determine the origin of atherosclerosis and the link between arterial status and pathobiological variables. This study incorporated 3400 autopsy reports (n = 2318 men; aged 0─96 years; 1928─2010) of persons who died by unnatural causes (suicide, homicide, accident). Age, sex, BMI, abdominal fat thickness, and arterial status of six vascular areas were gathered. The arterial state was divided into five subgroups according to its status. BMI declined from 22.82 kg/m2 in 1931 to 18.43 kg/m
Identifiants
pubmed: 39448710
doi: 10.1038/s41598-024-76817-9
pii: 10.1038/s41598-024-76817-9
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
25179Subventions
Organisme : University of Szeged Open Access Fund
ID : 7030
Organisme : University of Szeged Open Access Fund
ID : 7030
Organisme : University of Szeged Open Access Fund
ID : 7030
Organisme : University of Szeged Open Access Fund
ID : 7030
Organisme : University of Szeged Open Access Fund
ID : 7030
Organisme : University of Szeged Open Access Fund
ID : 7030
Organisme : University of Szeged Open Access Fund
ID : 7030
Organisme : University of Szeged Open Access Fund
ID : 7030
Informations de copyright
© 2024. The Author(s).
Références
WHO | World Health Organization. WHO [Internet]. (2018). http://www.who.int/en/ . . Accessed 22 Jan 2018
Ross, R. Atherosclerosis—an inflammatory disease. N Engl. J. Med. 340, 115–126 (1999).
doi: 10.1056/NEJM199901143400207
pubmed: 9887164
Libby, P., Ridker, P. M. & Hansson, G. K. Inflammation in atherosclerosis: from pathophysiology to practice. J. Am. Coll. Cardiol. 54, 2129–2138 (2009).
doi: 10.1016/j.jacc.2009.09.009
pubmed: 19942084
pmcid: 2834169
Burke, A. P. et al. Coronary risk factors and plaque morphology in men with coronary disease who died suddenly. N Engl. J. Med. 336, 1276–1282 (1997).
doi: 10.1056/NEJM199705013361802
pubmed: 9113930
Strong, J. P. et al. Prevalence and extent of atherosclerosis in adolescents and young adults. Jama. 281, 727–735 (1999).
doi: 10.1001/jama.281.8.727
pubmed: 10052443
La Russa, R. et al. Postmortem computed tomography angiography (PMCTA) and traditional autopsy in cases of sudden cardiac death due to coronary artery disease: a systematic review and meta-analysis. Radiol. Med. (Torino). 124, 109–117 (2019).
doi: 10.1007/s11547-018-0943-y
pubmed: 30259270
Fan, J., Watanabe, T. & Atherosclerosis Known and unknown. Pathol. Int. 72, 151–160 (2022).
doi: 10.1111/pin.13202
pubmed: 35076127
Enos, W. F., Holmes, R. H. & Beyer, J. Coronary disease among United States soldiers killed in action in Korea; preliminary report. J. Am. Med. Assoc. 152, 1090–1093 (1953).
doi: 10.1001/jama.1953.03690120006002
pubmed: 13052433
Andersson, C., Johnson, A. D., Benjamin, E. J., Levy, D. & Vasan, R. S. 70-year legacy of the Framingham Heart Study. Nat. Rev. Cardiol. 16, 687–698 (2019).
doi: 10.1038/s41569-019-0202-5
pubmed: 31065045
Ravelli, G. P., Stein, Z. A. & Susser, M. W. Obesity in young men after famine exposure in utero and early infancy. N Engl. J. Med. 295, 349–353 (1976).
doi: 10.1056/NEJM197608122950701
pubmed: 934222
Stanner, S. A. et al. Does malnutrition in utero determine diabetes and coronary heart disease in adulthood? Results from the Leningrad siege study, a cross sectional study. BMJ. 315, 1342–1348 (1997).
doi: 10.1136/bmj.315.7119.1342
pubmed: 9402775
pmcid: 2127836
Ojha, S., Robinson, L., Symonds, M. E. & Budge, H. Suboptimal maternal nutrition affects offspring health in adult life. Early Hum. Dev. 89, 909–913 (2013).
doi: 10.1016/j.earlhumdev.2013.08.022
pubmed: 24080391
Oken, E. & Gillman, M. W. Fetal origins of obesity. Obes. Res. 11, 496–506 (2003).
doi: 10.1038/oby.2003.69
pubmed: 12690076
Rogers, I. & EURO-BLCS Study Group. The influence of birthweight and intrauterine environment on adiposity and fat distribution in later life. Int. J. Obes. Relat. Metab. Disord J. Int. Assoc. Study Obes. 27, 755–777 (2003).
doi: 10.1038/sj.ijo.0802316
Gurven, M. et al. Inflammation and infection do not promote arterial aging and Cardiovascular Disease Risk factors among lean horticulturalists. PLoS One 4, e6590 (2009).
Wang, P-X., Wang, J-J., Lei, Y-X., Xiao, L. & Luo, Z-C. Impact of fetal and infant exposure to the Chinese great famine on the risk of hypertension in adulthood. PLoS One. 7, e49720 (2012).
doi: 10.1371/journal.pone.0049720
pubmed: 23185416
pmcid: 3504120
Benjamin, E. J. et al. Heart Disease and Stroke Statistics-2019 update: a Report from the American Heart Association. Circulation. 139, e56–528 (2019).
doi: 10.1161/CIR.0000000000000659
pubmed: 30700139
Vagelos, P. R. Are prescription drug prices high? Science. 252, 1080–1084 (1991).
doi: 10.1126/science.252.5009.1080
pubmed: 2031182
Vagelos, P. R., Galambos, L. & Medicine Science and Merck (Cambridge University Press, 2004).
Scandinavian Simvastatin Survival Study Group. Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the scandinavian simvastatin survival study (4S). Lancet Lond. Engl. 344, 1383–1389. (1994).
Shepherd, J. et al. Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. N Engl. J. Med. 333, 1301–1308 (1995).
doi: 10.1056/NEJM199511163332001
pubmed: 7566020
Steinberg, D. Thematic review series: the pathogenesis of atherosclerosis. An interpretive history of the cholesterol controversy, part V: the discovery of the statins and the end of the controversy. J. Lipid Res. 47, 1339–1351 (2006).
doi: 10.1194/jlr.R600009-JLR200
pubmed: 16585781
Li, Y. et al. Healthy lifestyle and life expectancy free of cancer, cardiovascular disease, and type 2 diabetes: prospective cohort study. BMJ. 368, l6669 (2020).
doi: 10.1136/bmj.l6669
pubmed: 31915124
pmcid: 7190036
Fredrick Cornhill, J. & Roach, M. R. A quantitative study of the localization of atherosclerotic lesions in the rabbit aorta. Atherosclerosis. 23, 489–501 (1976).
doi: 10.1016/0021-9150(76)90009-5
Mitchell Arterial disease - Blackwell Scientific Publications.1965.
Caro, C. G., Fitz-Gerald, J. M. & Schroter, R. C. Atheroma and arterial wall shear. Observation, correlation and proposal of a shear dependent mass transfer mechanism for atherogenesis. Proc. R Soc. Lond. B Biol. Sci. 177, 109–159 (1971).
doi: 10.1098/rspb.1971.0019
pubmed: 4396262
Svindland, A. & Walløe, L. Distribution pattern of sudanophilic plaques in the descending thoracic and proximal abdominal human aorta. Atherosclerosis. 57, 219–224 (1985).
doi: 10.1016/0021-9150(85)90035-8
pubmed: 3841284
Cornhill, J. F., Herderick, E. E. & Stary, H. C. Topography of human aortic sudanophilic lesions. Monogr. Atheroscler. 15, 13–19 (1990).
pubmed: 2296239
Günenç Beşer, C., Karcaaltıncaba, M., Çelik, H. H. & Başar, R. The prevalence and distribution of the atherosclerotic plaques in the abdominal aorta and its branches. Folia Morphol. 75, 364–375 (2016).
doi: 10.5603/FM.a2016.0005
Razavi, A. C. et al. Early contributors to healthy arterial aging versus premature atherosclerosis in young adults: the Bogalusa Heart Study. J. Am. Heart Assoc. 10, e020774 (2021).
doi: 10.1161/JAHA.121.020774
pubmed: 34096330
pmcid: 8477892
Mahoney, L. T. et al. Coronary risk factors measured in childhood and young adult life are associated with coronary artery calcification in young adults: the Muscatine study. J. Am. Coll. Cardiol. 27, 277–284 (1996).
doi: 10.1016/0735-1097(95)00461-0
pubmed: 8557894
Raitakari, O. T. et al. Cohort profile: the cardiovascular risk in Young finns Study. Int. J. Epidemiol. 37, 1220–1226 (2008).
doi: 10.1093/ije/dym225
pubmed: 18263651
Virdis, A. et al. Mechanisms responsible for endothelial dysfunction associated with acute estrogen deprivation in normotensive women. Circulation. 101, 2258–2263 (2000).
doi: 10.1161/01.CIR.101.19.2258
pubmed: 10811592
Maas, A. H. E. M. & Appelman, Y. E. A. Gender differences in coronary heart disease. Neth. Heart J. 18, 598–603 (2010).
doi: 10.1007/s12471-010-0841-y
pubmed: 21301622
pmcid: 3018605
Kachur, S., Lavie, C. J., de Schutter, A., Milani, R. V. & Ventura, H. O. Obesity and cardiovascular diseases. Minerva Med. 108, 212–228 (2017).
doi: 10.23736/S0026-4806.17.05022-4
pubmed: 28150485