Epidemiological, Clinical, and Histopathological Features of the Head and Neck Region Schwannomas-Our Experience in the Western Part of Romania with Surgical Insights.

head and neck schwannomas immunohistochemical reaction maxillofacial pathology oral pathology

Journal

Diagnostics (Basel, Switzerland)
ISSN: 2075-4418
Titre abrégé: Diagnostics (Basel)
Pays: Switzerland
ID NLM: 101658402

Informations de publication

Date de publication:
20 Oct 2024
Historique:
received: 17 09 2024
revised: 15 10 2024
accepted: 18 10 2024
medline: 25 10 2024
pubmed: 25 10 2024
entrez: 25 10 2024
Statut: epublish

Résumé

Schwannomas are benign solitary, slow-growing, encapsulated, asymptomatic tumors arising from Schwann's sheath of nervous fibers. The current paper presents all the cases diagnosed with different types of schwannomas in the head and neck region between January 2009 and December 2023 in the Western part of Romania. In this period, ten cases of schwannoma were identified. The pathological exams were performed at the Department of Pathology using morphological Hematoxylin-Eosin staining. In addition, immunohistochemical reactions were used in order to confirm the diagnosis. Demographic and clinical data, imaging features, surgical approach, and morphological and immunohistochemical aspects are presented. The results also display an impressive clinical picture of a gigantic ancient schwannoma. This retrospective study describes our experience with head and neck schwannomas, the diagnostic methods available, the surgical decisions, and the histopathological aspects while analyzing the data and reviewing the published specialized literature in the English language.

Identifiants

pubmed: 39451657
pii: diagnostics14202334
doi: 10.3390/diagnostics14202334
pii:
doi:

Types de publication

Journal Article

Langues

eng

Auteurs

Adrian Nicoara (A)

Discipline of Dentoalveolar Surgery, "Victor Babes" University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Oro-Maxillo-Facial Surgery Clinic, Emergency City Hospital, 300062 Timisoara, Romania.

Marina Rakitovan (M)

Oro-Maxillo-Facial Surgery Clinic, Emergency City Hospital, 300062 Timisoara, Romania.
Department of Microscopic Morphology, University of Medicine and Pharmacy "Victor Babes", 300041 Timisoara, Romania.

Raluca Maria Closca (RM)

Department of Microscopic Morphology, University of Medicine and Pharmacy "Victor Babes", 300041 Timisoara, Romania.
Department of Pathology, Emergency City Hospital, 300254 Timisoara, Romania.

Marius Militaru (M)

Department of Neuroscience, Discipline of Neurology II, "Victor Babes" University of Medicine and Pharmacy, Municipal Emergency Hospital Timisoara, 300041 Timisoara, Romania.

Alexandru-Cristian Cindrea (AC)

Department of Surgery, "Victor Babes" University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Department of Emergency, Emergency City Hospital, 300079 Timisoara, Romania.

Flavia Zara (F)

Department of Microscopic Morphology, University of Medicine and Pharmacy "Victor Babes", 300041 Timisoara, Romania.
Department of Pathology, Emergency City Hospital, 300254 Timisoara, Romania.

Classifications MeSH