Endocrine-Disruptive Effects of Adenylate Cyclase Activator Forskolin: In Vitro and In Vivo Evidence.
H295R
endocrine disruption
forskolin
medaka
steroidogenesis
Journal
Toxics
ISSN: 2305-6304
Titre abrégé: Toxics
Pays: Switzerland
ID NLM: 101639637
Informations de publication
Date de publication:
27 Sep 2024
27 Sep 2024
Historique:
received:
28
08
2024
revised:
14
09
2024
accepted:
24
09
2024
medline:
25
10
2024
pubmed:
25
10
2024
entrez:
25
10
2024
Statut:
epublish
Résumé
Forskolin (FSK) is a potent adenylate cyclase activator and may display endocrine-disruptive effects via the disruption of steroidogenesis. Here, we tested this hypothesis by use of the in vitro H295R steroidogenesis assay and the in vivo long-term medaka (
Identifiants
pubmed: 39453121
pii: toxics12100701
doi: 10.3390/toxics12100701
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : the National Natural Science Foundation of China
ID : 21107003