Plant-Based Anticancer Compounds With a Focus on Breast Cancer.


Journal

Cancer reports (Hoboken, N.J.)
ISSN: 2573-8348
Titre abrégé: Cancer Rep (Hoboken)
Pays: United States
ID NLM: 101747728

Informations de publication

Date de publication:
Oct 2024
Historique:
revised: 11 07 2024
received: 18 10 2023
accepted: 11 08 2024
medline: 25 10 2024
pubmed: 25 10 2024
entrez: 25 10 2024
Statut: ppublish

Résumé

Breast cancer is a common form of cancer among women characterized by the growth of malignant cells in the breast tissue. The most common treatments for this condition include chemotherapy, surgical intervention, radiation therapy, hormone therapy, and biological therapy. The primary issues associated with chemotherapy and radiation therapy are their adverse events and significant financial burden among patients in underdeveloped countries. This highlights the need to explore and develop superior therapeutic options that are less detrimental and more economically efficient. Plants provide an abundant supply of innovative compounds and present a promising new avenue for investigating cancer. Plants and their derivations are undergoing a revolution due to their reduced toxicity, expediency, cost-effectiveness, safety, and simplicity in comparison to conventional treatment methods. Natural products are considered promising candidates for the development of anticancer drugs, due perhaps to the diverse pleiotropic effects on target events. The effects of plant-derived products are limited to cancer cells while leaving healthy cells unaffected. Identification of compounds with strong anticancer properties and development of plant-based medications for cancer treatment might be crucial steps in breast cancer therapy. Although bioactive compounds have potent anticancer properties, they also have drawbacks that need to be resolved before their application in clinical trials and improved for the approved drugs. This study aims to give comprehensive information on known anticancer compounds, including their sources and molecular mechanisms of actions, along with opportunities and challenges in plant-based anticancer therapies.

Identifiants

pubmed: 39453820
doi: 10.1002/cnr2.70012
doi:

Substances chimiques

Antineoplastic Agents, Phytogenic 0
Biological Products 0
Plant Extracts 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

e70012

Informations de copyright

© 2024 The Author(s). Cancer Reports published by Wiley Periodicals LLC.

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Auteurs

Amin Moradi Hasan-Abad (AM)

Autoimmune Diseases Research Center, Kashan University of Medical Sciences, Kashan, Iran.

Amir Atapour (A)

Department of Medical Biotechnology, School of Advanced Medical Sciences and Technologies, Shiraz University of Medical Sciences, Shiraz, Iran.

Ali Sobhani-Nasab (A)

Autoimmune Diseases Research Center, Kashan University of Medical Sciences, Kashan, Iran.

Hossein Motedayyen (H)

Autoimmune Diseases Research Center, Kashan University of Medical Sciences, Kashan, Iran.

Reza ArefNezhad (R)

Department of Anatomy, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.

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