Lambda carrageenan displays antiviral activity against the infectious pancreatic necrosis virus (IPNV) by inhibiting viral replication and enhancing innate immunity in salmonid cells.

Antiviral activity Cytokines IPNV Lambda carrageenan Salmonid cells Viral replication

Journal

International journal of biological macromolecules
ISSN: 1879-0003
Titre abrégé: Int J Biol Macromol
Pays: Netherlands
ID NLM: 7909578

Informations de publication

Date de publication:
23 Oct 2024
Historique:
received: 09 06 2024
revised: 16 10 2024
accepted: 22 10 2024
medline: 26 10 2024
pubmed: 26 10 2024
entrez: 25 10 2024
Statut: aheadofprint

Résumé

Sulfated polysaccharide lambda carrageenan (λ-CGN) was evaluated for its antiviral effect against IPNV using the in vitro infection model of CHSE-214 salmonid cells. A plaque reduction lysis assay revealed that λ-CGN has an IC

Identifiants

DOI: 10.1016/j.ijbiomac.2024.136875 PMID: 39454921
pubmed: 39454921
pii: S0141-8130(24)07684-0
doi: 10.1016/j.ijbiomac.2024.136875
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

136875

Informations de copyright

Copyright © 2024. Published by Elsevier B.V.

Déclaration de conflit d'intérêts

Declaration of competing interest Authors declare no conflict of interests.

Auteurs

Daniela Espinoza (D)

Laboratorio de Inmunología, Centro de Biotecnología Acuícola (CBA), Departamento de Biología, Facultad de Química y Biología, Universidad de Santiago de Chile., Alameda, 3363 Santiago, Chile; Laboratory of Marine Biotechnology, Faculty of Chemistry and Biology, University of Santiago de Chile, Biology, Alameda, 3363 Santiago, Chile.

Daniel Laporte (D)

Laboratory of Plant Physiology and Molecular Biology, Instituto de Ciencias Biomédicas, Universidad Autónoma de Chile, Talca 3467987, Chile.

Fabián Martínez (F)

Laboratory of Marine Biotechnology, Faculty of Chemistry and Biology, University of Santiago de Chile, Biology, Alameda, 3363 Santiago, Chile.

Ana María Sandino (AM)

Laboratorio de Virología, Centro de Biotecnología Acuícola (CBA), Departamento de Biología, Facultad de Química y Biología, Universidad de Santiago de Chile., Alameda, 3363 Santiago, Chile.

Natalia Valdés (N)

Laboratorio de Inmunología, Centro de Biotecnología Acuícola (CBA), Departamento de Biología, Facultad de Química y Biología, Universidad de Santiago de Chile., Alameda, 3363 Santiago, Chile.

Alejandra Moenne (A)

Laboratory of Marine Biotechnology, Faculty of Chemistry and Biology, University of Santiago de Chile, Biology, Alameda, 3363 Santiago, Chile.

Mónica Imarai (M)

Laboratorio de Inmunología, Centro de Biotecnología Acuícola (CBA), Departamento de Biología, Facultad de Química y Biología, Universidad de Santiago de Chile., Alameda, 3363 Santiago, Chile. Electronic address: monica.imarai@usach.cl.

Classifications MeSH