Dietary selenium intake, hypertension and cognitive function among US adults, NHANES 2011-2014.
Cognitive function
Dietary selenium
Hypertension
NHANES
Older adults
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
25 Oct 2024
25 Oct 2024
Historique:
received:
16
02
2024
accepted:
07
10
2024
medline:
26
10
2024
pubmed:
26
10
2024
entrez:
25
10
2024
Statut:
epublish
Résumé
Dietary selenium intake and hypertension were associated with cognitive function, but it was limitedly understood whether the effect of selenium intake on cognitive function in older adults was modified by hypertension status. A total of 2416 participants aged ≥ 60 years old from the National Health and Nutrition Examination Survey in 2011-2014 were involved in this study. Selenium intake from foods was estimated using two non-consecutive 24-hour dietary recalls. Blood pressure was measured by trained personnel or physicians at a mobile testing center. Cognitive function was measured by Registry for Alzheimer's disease (CERAD), the Animal Fluency test (AFT), and Digit Symbol Substitution Test (DSST). Among 2,416 participants, we found that higher dietary intake of selenium was associated with higher score on most tests (CERAD: Total Score: P for trend = 0.01; AFT: P for trend = 0.01; DSST: P for trend = 0.02) and hypertension was associated with lower score on each test (CEARD: Total Score (β = - 0.87, P = 0.03), CERAD: Delayed Recall Score (β = - 0.37, P = 0.04), AFT (β = - 0.88, P = 0.03), and DSST (β = - 2.72, P = 0.02). The interaction of hypertension status and dietary selenium intake on CERAD-immediate (P for interaction = 0.02) and DSST (P for interaction = 0.04) were statistical significance. In addition, hypertension did not mediate the association between dietary selenium intake and the four dimensions of cognition. The findings suggest that in older adults with hypertension, higher dietary selenium intake is associated with improved cognitive function, implying a potential nutritional strategy for preventing cognitive impairment in this population.
Identifiants
pubmed: 39455607
doi: 10.1038/s41598-024-75652-2
pii: 10.1038/s41598-024-75652-2
doi:
Substances chimiques
Selenium
H6241UJ22B
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
25346Subventions
Organisme : National Natural Science Foundation of China
ID : 82070362
Organisme : Jilin Province Specialized Program for Medical and Health Personnel
ID : JLSWSRCZX2021-033
Informations de copyright
© 2024. The Author(s).
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