High-Throughput Luminescence-Based Serum Bactericidal Assay Optimization and Characterization to Assess Human Sera Functionality Against Multiple
Humans
Shigella flexneri
/ immunology
Serogroup
Dysentery, Bacillary
/ immunology
Antibodies, Bacterial
/ immunology
High-Throughput Screening Assays
/ methods
Animals
Luminescent Measurements
/ methods
Immunoglobulin G
/ blood
Luminescence
Rabbits
O Antigens
/ immunology
Blood Bactericidal Activity
SBA
Shigella
functional assay
human serum
vaccine
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
16 Oct 2024
16 Oct 2024
Historique:
received:
02
09
2024
revised:
02
10
2024
accepted:
10
10
2024
medline:
26
10
2024
pubmed:
26
10
2024
entrez:
26
10
2024
Statut:
epublish
Résumé
Shigellosis represents a significant global health concern particularly affecting children under 5 years in low- and middle-income countries (LMICs) and is associated with stunting and antimicrobial resistance. There is a critical need for an effective vaccine offering broad protection against the different
Identifiants
pubmed: 39456904
pii: ijms252011123
doi: 10.3390/ijms252011123
pii:
doi:
Substances chimiques
Antibodies, Bacterial
0
Immunoglobulin G
0
O Antigens
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM