Biological Activity Evaluation of Phenolic Isatin-3-Hydrazones Containing a Quaternary Ammonium Center of Various Structures.

Hydrazones / chemistry Anti-Bacterial Agents / pharmacology Quaternary Ammonium Compounds / chemistry Antioxidants / pharmacology Microbial Sensitivity Tests Isatin / chemistry Animals Humans Methicillin-Resistant Staphylococcus aureus / drug effects Platelet Aggregation / drug effects Structure-Activity Relationship
antioxidants cytotoxicity hemostasis hydrazones isatin quaternary ammonium compounds

Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
17 Oct 2024
Historique:
received: 03 09 2024
revised: 02 10 2024
accepted: 07 10 2024
medline: 26 10 2024
pubmed: 26 10 2024
entrez: 26 10 2024
Statut: epublish

Résumé

A series of new isatin-3-hydrazones bearing different ammonium fragments was synthesized by a simple and easy work-up reaction of Girard's reagents analogs with 1-(3,5-di-

Identifiants

DOI: 10.3390/ijms252011130 PMID: 39456912
pubmed: 39456912
pii: ijms252011130
doi: 10.3390/ijms252011130
pii:
doi:

Substances chimiques

Hydrazones 0
Anti-Bacterial Agents 0
Quaternary Ammonium Compounds 0
Antioxidants 0
Isatin 82X95S7M06

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : the Science Committee of the Ministry of Science and Higher Education of the Republic of Kazakhstan
ID : Grant No. AP23490056
Organisme : Ministry of Science and Higher Education of the Russian Federation at FRC Kazan Scientific Center
ID : Grant No. 075-15-2022-1128

Auteurs

Margarita Neganova (M)

Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, Akad. Arbuzov st. 8, 420088 Kazan, Russia.
Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, 119991 Moscow, Russia.
Laboratory of Engineering Profile "Physical and Chemical Methods of Analysis", Korkyt Ata Kyzylorda University, Ayteke bi, Str., 29A, Kyzylorda 120014, Kazakhstan.
ORCID: 0000-0001-9346-5920

Yulia Aleksandrova (Y)

Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, Akad. Arbuzov st. 8, 420088 Kazan, Russia.
Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, 119991 Moscow, Russia.
Laboratory of Engineering Profile "Physical and Chemical Methods of Analysis", Korkyt Ata Kyzylorda University, Ayteke bi, Str., 29A, Kyzylorda 120014, Kazakhstan.
ORCID: 0000-0002-5370-3370

Alexandra Voloshina (A)

Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, Akad. Arbuzov st. 8, 420088 Kazan, Russia.

Anna Lyubina (A)

Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, Akad. Arbuzov st. 8, 420088 Kazan, Russia.
ORCID: 0000-0002-2816-8142

Nurbol Appazov (N)

Laboratory of Engineering Profile "Physical and Chemical Methods of Analysis", Korkyt Ata Kyzylorda University, Ayteke bi, Str., 29A, Kyzylorda 120014, Kazakhstan.
"CNEC" LLP, Dariger Ali Lane, 2, Kyzylorda 120001, Kazakhstan.
ORCID: 0000-0001-8765-3386

Sholpan Yespenbetova (S)

Laboratory of Engineering Profile "Physical and Chemical Methods of Analysis", Korkyt Ata Kyzylorda University, Ayteke bi, Str., 29A, Kyzylorda 120014, Kazakhstan.

Zulfiia Valiullina (Z)

Department of Pharmacology, Bashkir State Medical University, Lenin st. 8, 450008 Ufa, Russia.
ORCID: 0009-0006-9107-0435

Aleksandr Samorodov (A)

Department of Pharmacology, Bashkir State Medical University, Lenin st. 8, 450008 Ufa, Russia.
ORCID: 0000-0001-9302-499X

Sergey Bukharov (S)

Department of Technology of Basic Organic and Petrochemical Synthesis, Kazan National Research Technological University, K. Marx Str. 68, 420015 Kazan, Russia.

Elmira Gibadullina (E)

Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, Akad. Arbuzov st. 8, 420088 Kazan, Russia.
Laboratory of Engineering Profile "Physical and Chemical Methods of Analysis", Korkyt Ata Kyzylorda University, Ayteke bi, Str., 29A, Kyzylorda 120014, Kazakhstan.

Anipa Tapalova (A)

Laboratory of Engineering Profile "Physical and Chemical Methods of Analysis", Korkyt Ata Kyzylorda University, Ayteke bi, Str., 29A, Kyzylorda 120014, Kazakhstan.

Andrei Bogdanov (A)

Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, Akad. Arbuzov st. 8, 420088 Kazan, Russia.

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Classifications MeSH

questionsmedicales.fr › Composés chimiques organiques › Hydrazines › Hydrazones › Biological Activity Evaluation of Phenolic...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-infectieux › Antibactériens › Biological Activity Evaluation of Phenolic...
questionsmedicales.fr › Composés chimiques organiques › Composés onium › Composés d'ammonium quaternaire › Biological Activity Evaluation of Phenolic...
questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Agents protecteurs › Antioxydants › Biological Activity Evaluation of Phenolic...
questionsmedicales.fr › Techniques d'investigation › Évaluation préclinique de médicament › Tests de sensibilité microbienne › Biological Activity Evaluation of Phenolic...
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › Indoles › Isatine › Biological Activity Evaluation of Phenolic...
questionsmedicales.fr › Eucaryotes › Animaux › Biological Activity Evaluation of Phenolic...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Biological Activity Evaluation of Phenolic...
questionsmedicales.fr › Bactéries › Bactéries à Gram positif › Cocci à Gram positif › Staphylococcaceae › Staphylococcus › Staphylococcus aureus › Staphylococcus aureus résistant à la méticilline › Biological Activity Evaluation of Phenolic...
questionsmedicales.fr › Phénomènes physiologiques respiratoires et circulatoires › Phénomènes physiogiques du sang › Hémostase › Activation plaquettaire › Agrégation plaquettaire › Biological Activity Evaluation of Phenolic...
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Phénomènes pharmacologiques › Relation structure-activité › Biological Activity Evaluation of Phenolic...