Enhancing Drug Solubility, Bioavailability, and Targeted Therapeutic Applications through Magnetic Nanoparticles.


Journal

Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009

Informations de publication

Date de publication:
13 Oct 2024
Historique:
received: 06 09 2024
revised: 09 10 2024
accepted: 11 10 2024
medline: 26 10 2024
pubmed: 26 10 2024
entrez: 26 10 2024
Statut: epublish

Résumé

Biological variability poses significant challenges in the development of effective therapeutics, particularly when it comes to drug solubility and bioavailability. Poor solubility across varying physiological conditions often leads to reduced absorption and inconsistent therapeutic outcomes. This review examines how nanotechnology, especially through the use of nanomaterials and magnetic nanoparticles, offers innovative solutions to enhance drug solubility and bioavailability. This comprehensive review focuses on recent advancements and approaches in nanotechnology. We highlight both the successes and remaining challenges in this field, emphasizing the role of continued innovation. Future research should prioritize developing universal therapeutic solutions, conducting interdisciplinary research, and leveraging personalized nanomedicine to address biological variability.

Identifiants

pubmed: 39459222
pii: molecules29204854
doi: 10.3390/molecules29204854
pii:
doi:

Substances chimiques

Magnetite Nanoparticles 0
Pharmaceutical Preparations 0
Drug Carriers 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Zhejiang Provincial Key Research and Development Project
ID : (No. 2024C03231)

Auteurs

Yue Zhuo (Y)

School of Biomedical Science and Engineering, South China University of Technology, Guangzhou 511442, China.

Yong-Gang Zhao (YG)

College of Biological and Environmental Engineering, Zhejiang Shuren University, Hangzhou 310015, China.

Yun Zhang (Y)

School of Materials Science and Engineering, NingboTech University, Ningbo 315100, China.

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Classifications MeSH