Enhancing Drug Solubility, Bioavailability, and Targeted Therapeutic Applications through Magnetic Nanoparticles.
biological variability
drug absorption
drug design
drug solubility
magnetic nanoparticles
nanotechnology
targeted drug delivery
therapeutic efficacy
Journal
Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009
Informations de publication
Date de publication:
13 Oct 2024
13 Oct 2024
Historique:
received:
06
09
2024
revised:
09
10
2024
accepted:
11
10
2024
medline:
26
10
2024
pubmed:
26
10
2024
entrez:
26
10
2024
Statut:
epublish
Résumé
Biological variability poses significant challenges in the development of effective therapeutics, particularly when it comes to drug solubility and bioavailability. Poor solubility across varying physiological conditions often leads to reduced absorption and inconsistent therapeutic outcomes. This review examines how nanotechnology, especially through the use of nanomaterials and magnetic nanoparticles, offers innovative solutions to enhance drug solubility and bioavailability. This comprehensive review focuses on recent advancements and approaches in nanotechnology. We highlight both the successes and remaining challenges in this field, emphasizing the role of continued innovation. Future research should prioritize developing universal therapeutic solutions, conducting interdisciplinary research, and leveraging personalized nanomedicine to address biological variability.
Identifiants
pubmed: 39459222
pii: molecules29204854
doi: 10.3390/molecules29204854
pii:
doi:
Substances chimiques
Magnetite Nanoparticles
0
Pharmaceutical Preparations
0
Drug Carriers
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Zhejiang Provincial Key Research and Development Project
ID : (No. 2024C03231)