Kinetic Studies on the Interaction of HIV-1 Gag Protein with the HIV-1 RNA Packaging Signal.
HIV-1
Psi
binding kinetics
packaging signal
protein–RNA interactions
Journal
Viruses
ISSN: 1999-4915
Titre abrégé: Viruses
Pays: Switzerland
ID NLM: 101509722
Informations de publication
Date de publication:
25 Sep 2024
25 Sep 2024
Historique:
received:
06
08
2024
revised:
20
09
2024
accepted:
22
09
2024
medline:
26
10
2024
pubmed:
26
10
2024
entrez:
26
10
2024
Statut:
epublish
Résumé
During HIV-1 virus assembly, the genomic RNA (vRNA) is selected for packaging by the viral protein Gag because it contains a specific packaging signal, Psi. While there have been numerous studies of Gag-Psi interactions, there is almost no information on the kinetic aspects of this interaction. We investigated the kinetics of Gag binding to different RNAs using switchSENSE DRX
Identifiants
pubmed: 39459852
pii: v16101517
doi: 10.3390/v16101517
pii:
doi:
Substances chimiques
gag Gene Products, Human Immunodeficiency Virus
0
RNA, Viral
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Research supported by Intramural Research Program, Center for Cancer Research, National Cancer Institute
ID : N.A.