Point-of-care breath sample analysis by semiconductor-based E-Nose technology discriminates non-infected subjects from SARS-CoV-2 pneumonia patients: a multi-analyst experiment.

COVID‐19 E‐Nose breath gas machine learning mass spectrometry metal oxide sensor pneumonia volatile organic compounds

Journal

MedComm
ISSN: 2688-2663
Titre abrégé: MedComm (2020)
Pays: China
ID NLM: 101769925

Informations de publication

Date de publication:
Nov 2024
Historique:
received: 26 02 2024
revised: 19 07 2024
accepted: 25 07 2024
medline: 28 10 2024
pubmed: 28 10 2024
entrez: 28 10 2024
Statut: epublish

Résumé

Metal oxide sensor-based electronic nose (E-Nose) technology provides an easy to use method for breath analysis by detection of volatile organic compound (VOC)-induced changes of electrical conductivity. Resulting signal patterns are then analyzed by machine learning (ML) algorithms. This study aimed to establish breath analysis by E-Nose technology as a diagnostic tool for severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) pneumonia within a multi-analyst experiment. Breath samples of 126 subjects with (

Identifiants

pubmed: 39465142
doi: 10.1002/mco2.726
pii: MCO2726
pmc: PMC11502717
doi:

Types de publication

Journal Article

Langues

eng

Pagination

e726

Informations de copyright

© 2024 The Author(s). MedComm published by Sichuan International Medical Exchange & Promotion Association (SCIMEA) and John Wiley & Sons Australia, Ltd.

Déclaration de conflit d'intérêts

A.K. and J.H. are employees of Airbus Defense & Space, and authors W.S. and D.L. are part of Lanz GmbH, and have no potential relevant financial or non‐financial interests to disclose. The other authors have no conflicts of interest to declare.

Auteurs

Tobias Woehrle (T)

Department of Anesthesiology LMU University Hospital Ludwig Maximilian University Munich Germany.

Florian Pfeiffer (F)

Department of Anesthesiology LMU University Hospital Ludwig Maximilian University Munich Germany.

Maximilian M Mandl (MM)

Institute for Medical Information Processing Biometry and Epidemiology Faculty of Medicine Ludwig Maximilian University Munich Germany.
Munich Center for Machine Learning Munich Germany.

Wolfgang Sobtzick (W)

LANZ GmbH Bergisch Gladbach Germany.

Jörg Heitzer (J)

Airbus Defence and Space GmbH Claude-Dornier-Straße Immenstaad Germany.

Alisa Krstova (A)

Airbus Defence and Space GmbH Claude-Dornier-Straße Immenstaad Germany.

Luzie Kamm (L)

Department of Anesthesiology LMU University Hospital Ludwig Maximilian University Munich Germany.

Matthias Feuerecker (M)

Department of Anesthesiology LMU University Hospital Ludwig Maximilian University Munich Germany.

Dominique Moser (D)

Department of Anesthesiology LMU University Hospital Ludwig Maximilian University Munich Germany.

Matthias Klein (M)

Emergency Department LMU University Hospital Ludwig Maximilian University Munich Germany.

Benedikt Aulinger (B)

Department of Medicine II LMU University Hospital Ludwig Maximilian University Munich Germany.

Michael Dolch (M)

Department of Anesthesiology LMU University Hospital Ludwig Maximilian University Munich Germany.
Department of Anesthesiology Inn Klinikum Altötting Germany.

Anne-Laure Boulesteix (AL)

Institute for Medical Information Processing Biometry and Epidemiology Faculty of Medicine Ludwig Maximilian University Munich Germany.
Munich Center for Machine Learning Munich Germany.

Daniel Lanz (D)

LANZ GmbH Bergisch Gladbach Germany.

Alexander Choukér (A)

Department of Anesthesiology LMU University Hospital Ludwig Maximilian University Munich Germany.

Classifications MeSH