Macrophage Membrane-Coated Nanoparticles for the Delivery of Natamycin Exhibit Increased Antifungal and Anti-Inflammatory Activities in Fungal Keratitis.

biocompatible nanoparticles fungal keratitis macrophage membranes natamycin therapeutic effects

Journal

ACS applied materials & interfaces
ISSN: 1944-8252
Titre abrégé: ACS Appl Mater Interfaces
Pays: United States
ID NLM: 101504991

Informations de publication

Date de publication:
28 Oct 2024
Historique:
medline: 28 10 2024
pubmed: 28 10 2024
entrez: 28 10 2024
Statut: aheadofprint

Résumé

This study aims to explore the efficacy and safety of macrophage membrane-coated nanoparticles for the delivery of natamycin (NAT) in the therapy of fungal keratitis (FK). Macrophage membranes were isolated and identified by immunofluorescence staining (IFS). NAT was encapsulated into poly(lactic-

Identifiants

pubmed: 39467057
doi: 10.1021/acsami.4c11366
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Auteurs

Xing Liu (X)

Department of Ophthalmology, the Affiliated Hospital of Qingdao University, 16 Jiangsu Road, Qingdao, Shandong Province 266003, China.

Yunfeng Zhang (Y)

Department of Ophthalmology, the Affiliated Hospital of Qingdao University, 16 Jiangsu Road, Qingdao, Shandong Province 266003, China.

Fang Peng (F)

Department of Ophthalmology, the Affiliated Hospital of Qingdao University, 16 Jiangsu Road, Qingdao, Shandong Province 266003, China.

Cui Li (C)

Department of Ophthalmology, the Affiliated Hospital of Qingdao University, 16 Jiangsu Road, Qingdao, Shandong Province 266003, China.

Qian Wang (Q)

Department of Ophthalmology, the Affiliated Hospital of Qingdao University, 16 Jiangsu Road, Qingdao, Shandong Province 266003, China.

Zhenhan Wang (Z)

Department of Ophthalmology, the Affiliated Hospital of Qingdao University, 16 Jiangsu Road, Qingdao, Shandong Province 266003, China.

Liting Hu (L)

Department of Ophthalmology, the Affiliated Hospital of Qingdao University, 16 Jiangsu Road, Qingdao, Shandong Province 266003, China.

Xudong Peng (X)

Department of Ophthalmology, the Affiliated Hospital of Qingdao University, 16 Jiangsu Road, Qingdao, Shandong Province 266003, China.

Guiqiu Zhao (G)

Department of Ophthalmology, the Affiliated Hospital of Qingdao University, 16 Jiangsu Road, Qingdao, Shandong Province 266003, China.

Jing Lin (J)

Department of Ophthalmology, the Affiliated Hospital of Qingdao University, 16 Jiangsu Road, Qingdao, Shandong Province 266003, China.

Classifications MeSH