An unusual case of aggressive endometrial adenocarcinoma metastasis to the clivus: illustrative case.

clivus tumor endometrial carcinoma malignant epithelial neoplasms neoplasm metastases skull base neoplasm

Journal

Journal of neurosurgery. Case lessons
ISSN: 2694-1902
Titre abrégé: J Neurosurg Case Lessons
Pays: United States
ID NLM: 9918227275606676

Informations de publication

Date de publication:
28 Oct 2024
Historique:
received: 19 06 2024
accepted: 25 07 2024
medline: 28 10 2024
pubmed: 28 10 2024
entrez: 28 10 2024
Statut: epublish

Résumé

Though endometrial carcinomas are a relatively common cancer of the female genitourinary tract, they rarely metastasize. Similarly, clival metastases make up a tiny fraction of all brain metastases. To the authors' knowledge, an endometrial carcinoma clival metastasis has never been described in the literature; therefore, the authors present the following unusual case of a 69-year-old female with a history of an initially grade 2 endometrial adenocarcinoma that metastasized to her clivus. Endometrial carcinoma has the potential to metastasize to the clivus. Endometrial carcinoma, even when initially low grade, can metastasize intracranially. Prompt diagnosis with tissue biopsy and radiation is the mainstay of treatment, although the prognosis remains poor. https://thejns.org/doi/10.3171/CASE24392.

Sections du résumé

BACKGROUND BACKGROUND
Though endometrial carcinomas are a relatively common cancer of the female genitourinary tract, they rarely metastasize. Similarly, clival metastases make up a tiny fraction of all brain metastases. To the authors' knowledge, an endometrial carcinoma clival metastasis has never been described in the literature; therefore, the authors present the following unusual case of a 69-year-old female with a history of an initially grade 2 endometrial adenocarcinoma that metastasized to her clivus.
OBSERVATIONS METHODS
Endometrial carcinoma has the potential to metastasize to the clivus.
LESSONS CONCLUSIONS
Endometrial carcinoma, even when initially low grade, can metastasize intracranially. Prompt diagnosis with tissue biopsy and radiation is the mainstay of treatment, although the prognosis remains poor. https://thejns.org/doi/10.3171/CASE24392.

Identifiants

pubmed: 39467324
doi: 10.3171/CASE24392
pii: CASE24392
doi:
pii:

Types de publication

Journal Article

Langues

eng

Auteurs

Breanna L Sheldon (BL)

Departments of Neurosurgery, University of Arizona, Tucson, Arizona.

Katherine Riordan (K)

University of Arizona School of Medicine, Tucson, Arizona.

Sara Fallahi (S)

Department of Pathology, Banner-University of Arizona Medical Center, Tucson, Arizona.

Shireen Samargandy (S)

Department of Otolaryngology-Head & Neck Surgery, King Abdulaziz University, Riyadh, Al-Malaz, Saudi Arabia.
Otolaryngology-Head & Neck Surgery, University of Arizona, Tucson, Arizona.

Christopher H Le (CH)

Otolaryngology-Head & Neck Surgery, University of Arizona, Tucson, Arizona.

Michael B Avery (MB)

Departments of Neurosurgery, University of Arizona, Tucson, Arizona.

Classifications MeSH