Normal ranges of left atrial phasic strains and strain rates by 2D speckle-tracking echocardiography in pediatrics: a systematic review and meta-analysis.
Left atrium
Meta-analysis
Normal range
Speckle-tracking echocardiography
Strain
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
29 10 2024
29 10 2024
Historique:
received:
26
04
2024
accepted:
14
10
2024
medline:
29
10
2024
pubmed:
29
10
2024
entrez:
29
10
2024
Statut:
epublish
Résumé
Establishing normal values of left atrial (LA) phasic strains and strain rates is essential for distinguishing between normal and abnormal functions, determining the degree of abnormality, and understanding the clinical significance of reported values in pediatrics. This meta-analysis aimed to establish normal values of two-dimensional speckle-tracking echocardiography (2DSTE)-derived LA phasic strains and strain rates in the pediatric population and identify the sources of inter-study heterogeneity for these values. A comprehensive search of PubMed, Scopus, and Embase databases was conducted using keywords such as "left atrial/left atrium," "strain/speckle/deformation," and "echocardiography" combined with pediatric age categories. Inclusion criteria comprised English-language human studies involving healthy subjects under 18 years of age. Subjects were categorized as neonates (up to 1 month), infants (1-12 months), and children (1-18 years). A random-effects model was applied to determine 2DSTE-derived LA strains and strain rates, and a meta-regression analysis was performed to investigate inter-study heterogeneity. Our analysis included 17 studies involving 1448 healthy subjects. For children, the mean values of LA strains during the reservoir, conduit, and contraction phases were 47.3% (95% CI 42.5-52.1%), 32.8% (95% CI 27.8-37.8%), and 12% (95% CI 10.0-14.1%), respectively. The mean values for LA strain rates were 2.4 s
Identifiants
pubmed: 39468239
doi: 10.1038/s41598-024-76411-z
pii: 10.1038/s41598-024-76411-z
doi:
Types de publication
Journal Article
Systematic Review
Meta-Analysis
Langues
eng
Sous-ensembles de citation
IM
Pagination
25888Informations de copyright
© 2024. The Author(s).
Références
Nagueh, S. F. & Khan, S. U. Left atrial strain for assessment of left ventricular diastolic function: focus on populations with normal LVEF. JACC Cardiovasc. Imaging. 16, 691–707. https://doi.org/10.1016/j.jcmg.2022.10.011 (2023).
doi: 10.1016/j.jcmg.2022.10.011
pubmed: 36752445
Kupczyńska, K., Mandoli, G. E., Cameli, M. & Kasprzak, J. D. Left atrial strain - a current clinical perspective. Kardiol Pol. 79, 955–964. https://doi.org/10.33963/KP.a2021.0105 (2021).
doi: 10.33963/KP.a2021.0105
pubmed: 34599503
Minocha, P. K. et al. Strain in children with MIS-C and acute COVID-19. Ann. Pediatr. Cardiol. 15, 459–466. https://doi.org/10.4103/apc.apc_93_22 (2022).
doi: 10.4103/apc.apc_93_22
pubmed: 37152504
Khoo, N. S. et al. The assessment of atrial function in single ventricle hearts from birth to Fontan: a speckle-tracking study by using strain and strain rate. J. Am. Soc. Echocardiogr. 26, 756–764. https://doi.org/10.1016/j.echo.2013.04.005 (2013).
doi: 10.1016/j.echo.2013.04.005
pubmed: 23669597
Kutty, S. et al. Functional maturation of left and right atrial systolic and diastolic performance in infants, children, and adolescents. J. Am. Soc. Echocardiogr. 26, 398–409e2. https://doi.org/10.1016/j.echo.2012.12.016 (2013).
doi: 10.1016/j.echo.2012.12.016
pubmed: 23337737
Mahfouz, R. A., Gomma, A., Goda, M. & Safwat, M. Relation of left atrial stiffness to insulin resistance in obese children: Doppler strain imaging study. Echocardiography. 32, 1157–1163. https://doi.org/10.1111/echo.12824 (2015).
doi: 10.1111/echo.12824
pubmed: 25363045
D’Ascenzi, F. et al. Atrial chamber remodelling in healthy pre-adolescent athletes engaged in endurance sports: a study with a longitudinal design. The CHILD study. Int. J. Cardiol. 223, 325–330. https://doi.org/10.1016/j.ijcard.2016.08.231 (2016).
doi: 10.1016/j.ijcard.2016.08.231
pubmed: 27543703
Kang, S. J., Ha, J., Hwang, S. J. & Kim, H. J. Long term outcomes of left atrial reservoir function in children with a history of Kawasaki disease. J. Cardiovasc. Ultrasound. 26, 26–32. https://doi.org/10.4250/jcu.2018.26.1.26 (2018).
doi: 10.4250/jcu.2018.26.1.26
pubmed: 29629021
pmcid: 5881081
Cantinotti, M. et al. Left and right atrial strain in healthy caucasian children by two-dimensional speckle-tracking echocardiography. J. Am. Soc. Echocardiogr. 32, 165–168e3. https://doi.org/10.1016/j.echo.2018.10.002 (2019).
doi: 10.1016/j.echo.2018.10.002
pubmed: 30459121
Sabatino, J. et al. Left atrial strain to identify diastolic dysfunction in children with cardiomyopathies. J. Clin. Med. 8, 1243. https://doi.org/10.3390/jcm8081243 (2019).
doi: 10.3390/jcm8081243
pubmed: 31426519
pmcid: 6722665
Jimbo, S. et al. Normal reference values for left atrial strains and strain rates in school children assessed using two-dimensional speckle-tracking echocardiography. Heart Vessels. 35, 1270–1280. https://doi.org/10.1007/s00380-020-01594-0 (2020).
doi: 10.1007/s00380-020-01594-0
pubmed: 32279107
Ifuku, M. et al. Left atrial dysfunction and stiffness in pediatric and adult patients with type 1 diabetes mellitus assessed with speckle tracking echocardiography. Pediatr. Diabetes. 22, 303–319. https://doi.org/10.1111/pedi.13141 (2021).
doi: 10.1111/pedi.13141
pubmed: 33094524
Matsubara, D. et al. Longitudinal assessment of cardiac outcomes of multisystem inflammatory syndrome in children associated with covid-19 infections. J. Am. Heart Assoc. 11, e023251. https://doi.org/10.1161/JAHA.121.023251 (2022).
doi: 10.1161/JAHA.121.023251
pubmed: 35043684
pmcid: 9238494
Aristizábal-Duque, C. H. et al. The assessment of myocardial longitudinal strain in a paediatric Spanish population using a new software analysis. J. Clin. Med. 11, 3272. https://doi.org/10.3390/jcm11123272 (2022).
doi: 10.3390/jcm11123272
pubmed: 35743343
pmcid: 9224625
Chang, H. Y. et al. Subclinical changes in left heart structure and function at preschool age in very low birth weight preterm infants. Front. Cardiovasc. Med. 9, 879952. https://doi.org/10.3389/fcvm.2022.879952 (2022).
doi: 10.3389/fcvm.2022.879952
pubmed: 35600491
pmcid: 9120602
Ficial, B. et al. Feasibility, reproducibility and reference ranges of left atrial strain in preterm and term neonates in the first 48 h of life. Diagnostics (Basel). 12, 350. https://doi.org/10.3390/diagnostics12020350 (2022).
doi: 10.3390/diagnostics12020350
pubmed: 35204441
Luo, S. L., Deng, Y., Lan, W. F., Yang, Y. H. & Dai, P. Echocardiographic evaluation of left atrial strain for predicting iron overload in pediatric patients with β-thalassemia with preserved ejection fraction. Int. J. Cardiovasc. Imaging. 39, 895–906. https://doi.org/10.1007/s10554-022-02788-5 (2023).
doi: 10.1007/s10554-022-02788-5
pubmed: 36607471
Chen, J. et al. Assessment of left heart dysfunction to predict doxorubicin cardiotoxicity in children with lymphoma. Front. Pediatr. 11, 1163664. https://doi.org/10.3389/fped.2023.1163664 (2023).
doi: 10.3389/fped.2023.1163664
pubmed: 37215605
pmcid: 10196234
Sabatino, J. et al. Mid- and long-term atrio-ventricular functional changes in children after recovery from COVID-19. J. Clin. Med. 12, 186. https://doi.org/10.3390/jcm12010186 (2022).
doi: 10.3390/jcm12010186
pubmed: 36614987
pmcid: 9820895
Zuckerberg, J. C. et al. Left atrial stiffness and strain are novel indices of left ventricular diastolic function in children: validation followed by application in multisystem inflammatory syndrome in children due to COVID-19. Eur. Heart J. Cardiovasc. Imaging. 24, 1241–1251. https://doi.org/10.1093/ehjci/jead087 (2023).
doi: 10.1093/ehjci/jead087
pubmed: 37159912
Sun, B. J. & Park, J. H. Echocardiographic measurement of left atrial strain - A key requirement in clinical practice. Circ. J. 86, 6–13. https://doi.org/10.1253/circj.CJ-21-0373 (2021).
doi: 10.1253/circj.CJ-21-0373
pubmed: 34092759
Jhaveri, S. et al. Left atrial strain and function in pediatric hypertrophic cardiomyopathy. J. Am. Soc. Echocardiogr. 34, 996–1006. https://doi.org/10.1016/j.echo.2021.04.014 (2021).
doi: 10.1016/j.echo.2021.04.014
pubmed: 33915246
Loar, R. W. et al. Left atrial strain correlates with elevated filling pressures in pediatric heart transplantation recipients. J. Am. Soc. Echocardiogr. 33, 504–511e1. https://doi.org/10.1016/j.echo.2019.11.004 (2020).
doi: 10.1016/j.echo.2019.11.004
pubmed: 31987750
Doan, T. T. et al. Left ventricular strain and left atrial strain are impaired during hemodialysis in children. Int. J. Cardiovasc. Imaging. 37, 3489–3497. https://doi.org/10.1007/s10554-021-02350-9 (2021).
doi: 10.1007/s10554-021-02350-9
pubmed: 34287747
Recher, M. et al. Assessment of left-ventricular diastolic function in pediatric intensive-care patients: a review of parameters and indications compared with those for adults. World J. Pediatr. 17, 21–30. https://doi.org/10.1007/s12519-020-00369-x (2021).
doi: 10.1007/s12519-020-00369-x
pubmed: 32506345
Page, M. J. et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ. 372, n71. https://doi.org/10.1136/bmj.n71 (2021).
doi: 10.1136/bmj.n71
pubmed: 33782057
pmcid: 8005924
Williams, K. et al. Standard 6: age groups for pediatric trials. Pediatrics. 129, S153–S160. https://doi.org/10.1542/peds.2012-0055I (2012).
doi: 10.1542/peds.2012-0055I
pubmed: 22661762
Downs, S. H. & Black, N. The feasibility of creating a checklist for the assessment of the methodological quality both of randomised and non-randomised studies of health care interventions. J. Epidemiol. Community Health. 52, 377–384. https://doi.org/10.1136/jech.52.6.377 (1998).
doi: 10.1136/jech.52.6.377
pubmed: 9764259
pmcid: 1756728
Truong, V. T. et al. Normal ranges of left ventricular strain by three-dimensional speckle-tracking echocardiography in adults: a systematic review and meta-analysis. J. Am. Soc. Echocardiogr. 32, 1586–1597e5. https://doi.org/10.1016/j.echo.2019.07.012 (2019).
doi: 10.1016/j.echo.2019.07.012
pubmed: 31611158
Pathan, F., D’Elia, N., Nolan, M. T., Marwick, T. H. & Negishi, K. Normal ranges of left atrial strain by speckle-tracking echocardiography: a systematic review and meta-analysis. J. Am. Soc. Echocardiogr. 30, 59–70e8. https://doi.org/10.1016/j.echo.2016.09.007 (2017).
doi: 10.1016/j.echo.2016.09.007
pubmed: 28341032
Jain, V. et al. Contemporary narrative review on left atrial strain mechanics in echocardiography: cardiomyopathy, valvular heart disease and beyond. Cardiovasc. Diagn. Ther. 11, 924–938. https://doi.org/10.21037/cdt-20-461 (2021).
doi: 10.21037/cdt-20-461
pubmed: 34295714
pmcid: 8261755
Yuda, S. Current clinical applications of speckle tracking echocardiography for assessment of left atrial function. J. Echocardiogr. 19, 129–140. https://doi.org/10.1007/s12574-021-00519-8 (2021).
doi: 10.1007/s12574-021-00519-8
pubmed: 33687616
Suzuki, K. et al. Influence of percutaneous occlusion of atrial septal defect on left atrial function evaluated using 2D speckle tracking echocardiography. Int. Heart J. 61, 83–88. https://doi.org/10.1536/ihj.19-173 (2020).
doi: 10.1536/ihj.19-173
pubmed: 31956134
Shakti, D. et al. Left atrial size and function in patients with congenital aortic valve stenosis. Am. J. Cardiol. 122, 1541–1545. https://doi.org/10.1016/j.amjcard.2018.07.027 (2018).
doi: 10.1016/j.amjcard.2018.07.027
pubmed: 30180956
Jashari, H. et al. Normal ranges of left ventricular strain in children: a meta-analysis. Cardiovasc. Ultrasound. 13, 37. https://doi.org/10.1186/s12947-015-0029-0 (2015).
doi: 10.1186/s12947-015-0029-0
pubmed: 26250696
pmcid: 4528396
Levy, P. T. et al. Normal ranges of right ventricular systolic and diastolic strain measures in children: a systematic review and meta-analysis. J. Am. Soc. Echocardiogr. 27 https://doi.org/10.1016/j.echo.2014.01.015 (2014). 549 – 60, e3.
Xiang, X., Zhu, X., Zheng, M. & Tang, Y. Comparison of two echocardiography-based methods for evaluating pediatric left ventricular diastolic dysfunction. Front. Pediatr. 11, 1206314. https://doi.org/10.3389/fped.2023.1206314 (2023).
doi: 10.3389/fped.2023.1206314
pubmed: 37732011
pmcid: 10507386
Sun, B. J. et al. Normal reference values for left atrial strain and its determinants from a large Korean multicenter registry. J. Cardiovasc. Imaging. 28, 186–198. https://doi.org/10.4250/jcvi.2020.0043 (2020).
doi: 10.4250/jcvi.2020.0043
pubmed: 32583635
pmcid: 7316554
Demircan, T. et al. Evaluation of left ventricular functions by speckle-tracking echocardiography in coarctation patients. Echocardiography. 38, 410–416. https://doi.org/10.1111/echo.14993 (2021).
doi: 10.1111/echo.14993
pubmed: 33576053
Pathan, F. et al. Left atrial strain: a multi-modality, multi-vendor comparison study. Eur. Heart J. Cardiovasc. Imaging. 22, 102–110. https://doi.org/10.1093/ehjci/jez303 (2021).
doi: 10.1093/ehjci/jez303
pubmed: 31848575
Ferkh, A. et al. Inter-vendor comparison of left atrial strain using layer specific strain analysis. Int. J. Cardiovasc. Imaging. 37, 1279–1288. https://doi.org/10.1007/s10554-020-02114-x (2021).
doi: 10.1007/s10554-020-02114-x
pubmed: 33389361
Wang, Y. et al. Left atrial strain reproducibility using vendor-dependent and vendor-independent software. Cardiovasc. Ultrasound. 17, 9. https://doi.org/10.1186/s12947-019-0158-y (2019).
doi: 10.1186/s12947-019-0158-y
pubmed: 31092263
pmcid: 6521472
Badano, L. P. et al. Standardization of left atrial, right ventricular, and right atrial deformation imaging using two-dimensional speckle tracking echocardiography: a consensus document of the EACVI/ASE/Industry Task Force to standardize deformation imaging. Eur. Heart J. Cardiovasc. Imaging. 19, 591–600. https://doi.org/10.1093/ehjci/jey042 (2018).
doi: 10.1093/ehjci/jey042
pubmed: 29596561
Russo, C. et al. Race-ethnic differences in subclinical left ventricular systolic dysfunction by global longitudinal strain: a community-based cohort study. Am. Heart J. 169, 721–726. https://doi.org/10.1016/j.ahj.2015.02.011 (2015).
doi: 10.1016/j.ahj.2015.02.011
pubmed: 25965720
pmcid: 4429251
Parke, K. S. et al. Ethnic differences in cardiac structure and function assessed by MRI in healthy south Asian and white European people: a UK Biobank Study. J. Cardiovasc. Magn. Reson. 26, 100001. https://doi.org/10.1016/j.jocmr.2023.100001 (2024).
doi: 10.1016/j.jocmr.2023.100001
pubmed: 38218434
pmcid: 11211094
El Amrousy, D. et al. Myocardial function using two dimension speckle-tracking echocardiography in children with celiac disease. Eur. J. Pediatr. 183, 947–954. https://doi.org/10.1007/s00431-023-05343-z (2024).
doi: 10.1007/s00431-023-05343-z
pubmed: 38060017
Delgado-Rodríguez, M. Systematic reviews of meta-analyses: applications and limitations. J. Epidemiol. Community Health. 60, 90–92. https://doi.org/10.1136/jech.2005.035253 (2006).
doi: 10.1136/jech.2005.035253
pubmed: 16415253
pmcid: 2566156
Levy, P. T. et al. Reference ranges of left ventricular strain measures by two-Dimensional Speckle-Tracking Echocardiography in children: a systematic review and Meta-analysis. J. Am. Soc. Echocardiogr. 29, 209–225e6. https://doi.org/10.1016/j.echo.2015.11.016 (2016).
doi: 10.1016/j.echo.2015.11.016
pubmed: 26747685