Humoral Immunity Profiling to Pandemic and Bat-Derived Coronavirus Variants: A Geographical Comparison.
SARS‐CoV‐2
antibodies
bats
betacoronaviruses
cross‐reactivity
Journal
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
ISSN: 2198-3844
Titre abrégé: Adv Sci (Weinh)
Pays: Germany
ID NLM: 101664569
Informations de publication
Date de publication:
29 Oct 2024
29 Oct 2024
Historique:
revised:
05
09
2024
received:
03
04
2024
medline:
29
10
2024
pubmed:
29
10
2024
entrez:
29
10
2024
Statut:
aheadofprint
Résumé
Dynamic pathogen exposure may impact the immunological response to SARS-CoV-2 (SCV2). One potential explanation for the lack of severe SCV2-related morbidity and mortality in Southeast Asia is prior exposure to related betacoronaviruses. Recent discoveries of SCV2-related betacoronaviruses from horseshoe bats (Rhinolophus sinicus) in Thailand, Laos, and Cambodia suggest the potential for bat-to-human spillover exposures in the region. In this work, serum antibodies to protein constructs from SCV2 and a representative bat coronavirus isolated in Cambodia (RshSTT182) are measured in pre-pandemic Cambodian human sera using ELISA assays. Of 293 Cambodian samples tested (N = 131 with acute malaria, n = 162 with acute undifferentiated febrile illness), 32 (10.9%) are seropositive for SCV2 based on established Spike and receptor-binding domain (RBD) cutoffs. Within SCV2 seropositive samples, 16 (50%) have higher antibody levels to antigens from the representative virus RshSTT182 versus SCV2 antigens; competitive binding ELISA assays demonstrate inhibition of reactivity to SCV2 Spike after pre-incubation with RshSTT182 Spike. Surrogate virus neutralization tests demonstrate that 8/30 (26.7%) SCV2 ELISA positive pre-pandemic Cambodian samples have neutralizing activity against SCV2, while 14/30 (46.7%) have activity against other SCV2-related betacoronaviruses. These data suggest that exposure to related betacoronaviruses may elicit cross-reactive immunity to SCV2 prior to the global pandemic.
Identifiants
pubmed: 39471070
doi: 10.1002/advs.202403503
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e2403503Subventions
Organisme : National Medical Research Council
ID : COVID-19RF-003
Organisme : National Medical Research Council
ID : OFLCG19May-0034
Organisme : Intramural Research Programs of the National Institute of Biomedical Imaging and Bioengineering and the National Institute of Allergy and Infectious Diseases, National Institutes of Health
Organisme : NIH HHS
Pays : United States
Informations de copyright
© 2024 The Author(s). Advanced Science published by Wiley‐VCH GmbH.
Références
L. M. Khosroshahi, M. Rokni, T. Mokhtari, F. Noorbakhsh, Int. Immunopharmacol. 2021, 93, 107364.
M. Rokni, V. Ghasemi, Z. Tavakoli, Rev. Med. Virol. 2020, 30, e2107.
M. Rokni, M. Sarhadi, M. Heidari Nia, L. Mohamed Khosroshahi, S. Asghari, S. Sargazi, S. Mirinejad, R. Saravani, Cell Biol. Int. 2022, 46, 1109.
M. Rokni, M. Heidari Nia, M. Sarhadi, S. Mirinejad, S. Sargazi, M. Moudi, R. Saravani, S. Rahdar, M. Kargar, Appl. Biochem. Biotechnol. 2022, 194, 3507.
M. Rokni, K. Ahmadikia, S. Asghari, S. Mashaei, F. Hassanali, BMC Infect. Dis. 2020, 20, 869.
M. Rokni, M. R. Hamblin, N. Rezaei, Hum. Vaccines Immunother. 2020, 16, 2363.
M. Heidari Nia, M. Rokni, S. Mirinejad, M. Kargar, S. Rahdar, S. Sargazi, M. Sarhadi, R. Saravani, J. Med. Virol. 2022, 94, 1502.
S. Sargazi, R. Sheervalilou, M. Rokni, M. Shirvaliloo, O. Shahraki, N. Rezaei, Cell Biol. Int. 2021, 45, 1599.
P. Kellam, W. Barclay, J. Gen. Virol. 2020, 101, 791.
K. W. Ng, N. Faulkner, G. H. Cornish, A. Rosa, R. Harvey, S. Hussain, R. Ulferts, C. Earl, A. G. Wrobel, D. J. Benton, C. Roustan, W. Bolland, R. Thompson, A. Agua‐Doce, P. Hobson, J. Heaney, H. Rickman, S. Paraskevopoulou, C. F. Houlihan, K. Thomson, E. Sanchez, G. Y. Shin, M. J. Spyer, D. Joshi, P. A. Walker, S. Kjaer, A. Riddell, C. Moore, B. R. Jebson, M. Wilkinson, et al., Science 2020, 370, 1339.
X.‐Y. Ge, N. Wang, W. Zhang, B. Hu, B. Li, Y.‐Z. Zhang, J.‐H. Zhou, C.‐M. Luo, X.‐L. Yang, L.‐J. Wu, B. Wang, Y. Zhang, Z.‐X. Li, Z.‐L. Shi, Virol. Sin. 2016, 31, 31.
J. Manning, I. Zaidi, C. Lon, L. A. Rosas, J.‐K. Park, A. Ponce, J. Bohl, S. Chea, M. Karkanitsa, S. Sreng, H. Rekol, C. M. Chour, D. Esposito, J. K. Taubenberger, M. J. Memoli, K. Sadtler, P. E. Duffy, F. Oliveira, Emerging Infect. Dis. 2022, 28, 440.
C. Yek, V. S. Nam, R. Leang, D. M. Parker, S. Heng, K. Souv, S. Sovannaroth, M. Mayxay, S. AbuBakar, R. T. Sasmono, N. D. Tran, H. K. L. Nguyen, C. Lon, K. Boonnak, R. Huy, L. Sovann, J. E. Manning, Front. Trop. Dis. 2021, 2, 46.
C.‐W. Tan, W.‐N. Chia, B. E. Young, F. Zhu, B.‐L. Lim, W.‐R. Sia, T.‐L. Thein, M. I.‐C. Chen, Y.‐S. Leo, D. C. Lye, L.‐F. Wang, N. Engl. J. Med. 2021, 385, 1401.
Coronaviruses closely related to the pandemic virus discovered in Japan and Cambodia, https://www.nature.com/articles/d41586‐020‐03217‐0 (accessed: November 2020).
S. Murakami, T. Kitamura, J. Suzuki, R. Sato, T. Aoi, M. Fujii, H. Matsugo, H. Kamiki, H. Ishida, A. Takenaka‐Uema, M. Shimojima, T. Horimoto, Emerging Infect. Dis. 2020, 26, 12.
N. Q. Huong, N. T. T. Nga, N. V. Long, B. D. Luu, A. Latinne, M. Pruvot, N. T. Phuong, L. T. V. Quang, V. V. Hung, N. T. Lan, N. T. Hoa, P. Q. Minh, N. T. Diep, N. Tung, V. D. Ky, S. I. Roberton, H. B. Thuy, N. V. Long, M. Gilbert, L. Wicker, J. A. K. Mazet, C. K. Johnson, T. Goldstein, A. Tremeau‐Bravard, V. Ontiveros, D. O. Joly, C. Walzer, A. E. Fine, S. H. Olson, PLoS One 2020, 15, e0237129.
A. Lacroix, V. Duong, V. Hul, S. San, H. Davun, K. Omaliss, S. Chea, A. Hassanin, W. Theppangna, S. Silithammavong, K. Khammavong, S. Singhalath, Z. Greatorex, A. E. Fine, T. Goldstein, S. Olson, D. O. Joly, L. Keatts, P. Dussart, A. Afelt, R. Frutos, P. Buchy, Infect., Genet. Evol. 2017, 48, 10.
S. Lapidus, F. Liu, A. Casanovas‐Massana, Y. Dai, J. D. Huck, C. Lucas, J. Klein, R. B. Filler, M. S. Strine, M. Sy, A. B. Deme, A. S. Badiane, B. Dieye, I. M. Ndiaye, Y. Diedhiou, A. M. Mbaye, C. T. Diagne, I. Vigan‐Womas, A. Mbengue, B. D. Sadio, M. M. Diagne, A. J. Moore, K. Mangou, F. Diallo, S. D. Sene, M. N. Pouye, R. Faye, B. Diouf, N. Nery, F. Costa, Sci. Rep. 2022, 12, 22175.
D. Delaune, V. Hul, E. A. Karlsson, A. Hassanin, T. P. Ou, A. Baidaliuk, F. Gámbaro, M. Prot, V. T. Tu, S. Chea, L. Keatts, J. Mazet, C. K. Johnson, P. Buchy, P. Dussart, T. Goldstein, E. Simon‐Lorière, V. Duong, Nat. Commun. 2021, 12, 6563.
C. Klumpp‐Thomas, H. Kalish, M. Drew, S. Hunsberger, K. Snead, M. P. Fay, J. Mehalko, A. Shunmugavel, V. Wall, P. Frank, J.‐P. Denson, M. Hong, G. Gulten, S. Messing, J. Hicks, S. Michael, W. Gillette, M. D. Hall, M. J. Memoli, D. Esposito, K. Sadtler, Nat. Commun. 2021, 12, 113.
E. Lisowska, Cell. Mol. Life Sci. 2002, 59, 445.
C. Bonomelli, K. J. Doores, D. C. Dunlop, V. Thaney, R. A. Dwek, D. R. Burton, M. Crispin, C. N. Scanlan, PLoS One 2011, 6, e23521.
M. Crispin, A. B. Ward, I. A. Wilson, Annu. Rev. Biophys. 2018, 47, 499.
K. J. Doores, FEBS J. 2015, 282, 4679.
B. Li, L. Wang, H. Ge, X. Zhang, P. Ren, Y. Guo, W. Chen, J. Li, W. Zhu, W. Chen, L. Zhu, F. Bai, Front. Chem. 2021, 9, 659764.
L. Unione, M. J. Moure, M. P. Lenza, I. Oyenarte, J. Ereño‐Orbea, A. Ardá, J. Jiménez‐Barbero, Angew. Chem. 2022, 134, e202201432.
L. Nguyen, K. A. McCord, D. T. Bui, K. M. Bouwman, E. N. Kitova, M. Elaish, D. Kumawat, G. C. Daskhan, I. Tomris, L. Han, P. Chopra, T.‐J. Yang, S. D. Willows, A. L. Mason, L. K. Mahal, T. L. Lowary, L. J. West, S.‐T. D. Hsu, T. Hobman, S. M. Tompkins, G.‐J. Boons, R. P. De Vries, M. S. Macauley, J. S. Klassen, Nat. Chem. Biol. 2022, 18, 81.
X.‐L. Sun, Glycobiology 2021, 31, 1245.
L. Liu, P. Wang, M. S. Nair, J. Yu, M. Rapp, Q. Wang, Y. Luo, J. F.‐W. Chan, V. Sahi, A. Figueroa, X. V. Guo, G. Cerutti, J. Bimela, J. Gorman, T. Zhou, Z. Chen, K.‐Y. Yuen, P. D. Kwong, J. G. Sodroski, M. T. Yin, Z. Sheng, Y. Huang, L. Shapiro, D. D. Ho, Nature 2020, 584, 450.
SEAR COVID‐19, https://experience.arcgis.com/experience/56d2642cb379485ebf78371e744b8c6a (accessed: September 2022).
L. O. Gostin, G. K. Gronvall, N. Engl. J. Med. 2023, 388, 2305.
J. D. H. Zuluaga, J. C. Santos‐Barbosa, A. Cuellar, C. J. Puerta, J. M. Gonzalez, Trop. Med. Int. Health 2022, 27, 1009.
L. C. Steinhardt, F. Ige, N. C. Iriemenam, S. M. Greby, Y. Hamada, M. Uwandu, M. Aniedobe, K. A. Stafford, A. Abimiku, N. Mba, N. Agala, O. Okunoye, A. Mpamugo, M. Swaminathan, E. Onokevbagbe, T. Olaleye, I. Odoh, B. J. Marston, M. Okoye, I. Abubakar, M. X. Rangaka, E. Rogier, R. Audu, J. Clin. Microbiol. 2021, 59, e00514.
F. Vanroye, D. V. den Bossche, I. Brosius, B. Tack, M. V. Esbroeck, J. Jacobs, Diagnostics 2021, 11, 1163.
M. A. M. Iesa, M. E. M. Osman, M. A. Hassan, A. I. A. Dirar, N. Abuzeid, J. J. Mancuso, R. Pandey, A. A. Mohammed, M. J. Borad, H. M. Babiker, E. H. E. Konozy, New Microbes New Infect. 2020, 38, 100817.
E. Lyimo, C. Fougeroux, A. Malabeja, J. Mbwana, P. M. Hayuma, E. Liheluka, L. Turner, S. Gesase, T. Lavstsen, J. P. A. Lusingu, D. T. R. Minja, C. W. Wang, BMC Infect. Dis. 2022, 22, 846.
L.‐F. Wang, B. T. Eaton, Wildlife and Emerging Zoonotic Diseases: The Biology, Circumstances and Consequences of Cross‐Species Transmission, Springer, Berlin, Germany 2007.
P. Zhou, X.‐L. Yang, X.‐G. Wang, B. Hu, L. Zhang, W. Zhang, H.‐R. Si, Y. Zhu, B. Li, C.‐L. Huang, H.‐D. Chen, J. Chen, Y. Luo, H. Guo, R.‐D. Jiang, M.‐Q. Liu, Y. Chen, X.‐R. Shen, X. Wang, X.‐S. Zheng, K. Zhao, Q.‐J. Chen, F. Deng, L.‐L. Liu, B. Yan, F.‐X. Zhan, Y.‐Y. Wang, G.‐F. Xiao, Z.‐L. Shi, Nature 2020, 579, 270.
S. Wacharapluesadee, C. W. Tan, P. Maneeorn, P. Duengkae, F. Zhu, Y. Joyjinda, T. Kaewpom, W. N. Chia, W. Ampoot, B. L. Lim, K. Worachotsueptrakun, V. C.‐W. Chen, N. Sirichan, C. Ruchisrisarod, A. Rodpan, K. Noradechanon, T. Phaichana, N. Jantarat, B. Thongnumchaima, C. Tu, G. Crameri, M. M. Stokes, T. Hemachudha, L.‐F. Wang, Nat. Commun. 2021, 12, 972.
M. Letko, A. Marzi, V. Munster, Nat. Microbiol. 2020, 5, 562.
S. Temmam, K. Vongphayloth, E. B. Salazar, S. Munier, M. Bonomi, B. Régnault, B. Douangboubpha, Y. Karami, D. Chretien, D. Sanamxay, V. Xayaphet, P. Paphaphanh, V. Lacoste, S. Somlor, K. Lakeomany, N. Phommavanh, P. Pérot, F. Donati, T. Bigot, M. Nilges, F. Rey, S. van der Werf, P. Brey, M. Eloit, Res. Square 2021, PPR396140.
C. Graham, J. Seow, I. Huettner, H. Khan, N. Kouphou, S. Acors, H. Winstone, S. Pickering, R. P. Galao, L. Dupont, M. J. Lista, J. M. Jimenez‐Guardeño, A. G. Laing, Y. Wu, M. Joseph, L. Muir, M. J. van Gils, W. M. Ng, H. M. E. Duyvesteyn, Y. Zhao, T. A. Bowden, M. Shankar‐Hari, A. Rosa, P. Cherepanov, L. E. McCoy, A. C. Hayday, S. J. D. Neil, M. H. Malim, K. J. Doores, Immunity 2021, 54, 1276.
E. Mathieu, H. Ritchie, L. Rodés‐Guirao, C. Appel, C. Giattino, J. Hasell, B. Macdonald, S. Dattani, Diana Beltekian, Esteban Ortiz‐Ospina, Max Roser, Coronavirus Pandemic (COVID‐19), https://ourworldindata.org/coronavirus (accessed: June 2024).
Y. C. F. Su, J. Z. J. Ma, T. P. Ou, L. Pum, S. Krang, P. Raftery, M. H. Kinzer, J. Bohl, V. Ieng, V. Kab, S. Patel, B. Sar, W. F. Ying, J. Jayakumar, V. S. Horm, N. Boukli, S. Yann, C. Troupin, V. Heang, J. A. Garcia‐Rivera, Y. Sengdoeurn, S. Heng, S. Lay, S. Chea, C. Darapheak, C. Savuth, A. Khalakdina, S. Ly, L. Baril, J. E. Manning, et al., Virus Evol. 2023, 9, veac121.
J. Mehalko, M. Drew, K. Snead, J.‐P. Denson, V. Wall, T. Taylor, K. Sadtler, S. Messing, W. Gillette, D. Esposito, Protein Expression Purif. 2021, 179, 105802.
J. Hicks, C. Klumpp‐Thomas, H. Kalish, A. Shunmugavel, J. Mehalko, J.‐P. Denson, K. R. Snead, M. Drew, K. S. Corbett, B. S. Graham, M. D. Hall, M. J. Memoli, D. Esposito, K. Sadtler, J. Clin. Immunol. 2021, 41, 906.
K. Miura, A. C. Orcutt, O. V. Muratova, L. H. Miller, A. Saul, C. A. Long, Vaccine 2008, 26, 193.
C. W. Tan, W. N. Chia, X. Qin, P. Liu, M. I.‐C. Chen, C. Tiu, Z. Hu, V. C.‐W. Chen, B. E. Young, W. R. Sia, Y.‐J. Tan, R. Foo, Y. Yi, D. C. Lye, D. E. Anderson, L.‐F. Wang, Nat. Biotechnol. 2020, 38, 1073.
R Core Team, R: A Language and Environment for Statistical Computing, R Foundation for Statistical Computing, Vienna, Austria, 2022, https://www.R‐project.org.