Lateral cell polarization drives organization of epithelia in sea anemone embryos and embryonic cell aggregates.


Journal

Proceedings of the National Academy of Sciences of the United States of America
ISSN: 1091-6490
Titre abrégé: Proc Natl Acad Sci U S A
Pays: United States
ID NLM: 7505876

Informations de publication

Date de publication:
12 Nov 2024
Historique:
medline: 29 10 2024
pubmed: 29 10 2024
entrez: 29 10 2024
Statut: ppublish

Résumé

One of the first organizing processes during animal development is the assembly of embryonic cells into epithelia. Common features unite epithelialization across select bilaterians, however, we know less about the molecular and cellular mechanisms that drive epithelial emergence in early branching nonbilaterians. In sea anemones, epithelia emerge both during embryonic development and after cell aggregation of dissociated tissues. Although adhesion is required to keep cells together, it is not clear whether cell polarization plays a role as epithelia emerge from disordered aggregates. Here, we use the embryos of the sea anemone

Identifiants

pubmed: 39471210
doi: 10.1073/pnas.2408763121
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e2408763121

Subventions

Organisme : HHS | NIH | National Institute of General Medical Sciences (NIGMS)
ID : R15GM141979-01
Organisme : NSF (NSF)
ID : MRI-2117798

Déclaration de conflit d'intérêts

Competing interests statement:The authors declare no competing interest.

Auteurs

Tavus Atajanova (T)

Department of Biology, Amherst College, Amherst, MA 01002.

Emily Minju Kang (EM)

Department of Biology, Amherst College, Amherst, MA 01002.

Anna Postnikova (A)

Department of Biology, Amherst College, Amherst, MA 01002.

Alivia Lee Price (AL)

Department of Biology, Amherst College, Amherst, MA 01002.

Sophia Doerr (S)

Department of Biology, Amherst College, Amherst, MA 01002.

Michael Du (M)

Department of Biology, Amherst College, Amherst, MA 01002.

Alicia Ugenti (A)

Department of Biology, Amherst College, Amherst, MA 01002.

Katerina Ragkousi (K)

Department of Biology, Amherst College, Amherst, MA 01002.

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Classifications MeSH