Lateral cell polarization drives organization of epithelia in sea anemone embryos and embryonic cell aggregates.
Nematostella vectensis
aggregate
epithelia
lateral polarity
lethal giant larvae
Journal
Proceedings of the National Academy of Sciences of the United States of America
ISSN: 1091-6490
Titre abrégé: Proc Natl Acad Sci U S A
Pays: United States
ID NLM: 7505876
Informations de publication
Date de publication:
12 Nov 2024
12 Nov 2024
Historique:
medline:
29
10
2024
pubmed:
29
10
2024
entrez:
29
10
2024
Statut:
ppublish
Résumé
One of the first organizing processes during animal development is the assembly of embryonic cells into epithelia. Common features unite epithelialization across select bilaterians, however, we know less about the molecular and cellular mechanisms that drive epithelial emergence in early branching nonbilaterians. In sea anemones, epithelia emerge both during embryonic development and after cell aggregation of dissociated tissues. Although adhesion is required to keep cells together, it is not clear whether cell polarization plays a role as epithelia emerge from disordered aggregates. Here, we use the embryos of the sea anemone
Identifiants
pubmed: 39471210
doi: 10.1073/pnas.2408763121
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e2408763121Subventions
Organisme : HHS | NIH | National Institute of General Medical Sciences (NIGMS)
ID : R15GM141979-01
Organisme : NSF (NSF)
ID : MRI-2117798
Déclaration de conflit d'intérêts
Competing interests statement:The authors declare no competing interest.