Humidifier-Related Lung Injury Leading to Hypersensitivity Pneumonitis: A Case Report.

allergy antigen community acquired pneumonia humidifier lung hypersensitivity pneumonitis (hp) nonfibrotic hypersensitivity pneumonitis prostate-specific membrane antigen

Journal

Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737

Informations de publication

Date de publication:
Sep 2024
Historique:
accepted: 25 09 2024
medline: 30 10 2024
pubmed: 30 10 2024
entrez: 30 10 2024
Statut: epublish

Résumé

Humidifier lung is a subtype of hypersensitivity pneumonitis (HP) triggered by repeated exposure to an antigen. The mainstay of therapy is antigen avoidance. A Caucasian male in his 30s presented with a six-month history of progressively worsening dyspnea and cough. On presentation, he was hypoxic on room air. Laboratory work was significant for a leukocytosis and a CT angiogram of the chest demonstrated diffuse ill-defined ground-glass opacities in both lungs. The patient was admitted for community-acquired pneumonia, but his symptoms worsened, so additional infectious and rheumatological work-up was obtained. History revealed the patient used a home humidifier daily for the past year. Cultures obtained from the humidifier grew

Identifiants

pubmed: 39473639
doi: 10.7759/cureus.70448
pmc: PMC11521319
doi:

Types de publication

Case Reports Journal Article

Langues

eng

Pagination

e70448

Informations de copyright

Copyright © 2024, Obregon et al.

Déclaration de conflit d'intérêts

Human subjects: Consent was obtained or waived by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.

Références

Respir Med. 2020 Nov - Dec;174:106196
pubmed: 33096316
Chest. 2021 Aug;160(2):e97-e156
pubmed: 33861992
BMC Pulm Med. 2015 Sep 30;15:108
pubmed: 26420433
Am J Respir Crit Care Med. 2010 Jun 15;181(12):1391-6
pubmed: 20167845
Int J Environ Res Public Health. 2021 Jun 06;18(11):
pubmed: 34204162
Medicine (Baltimore). 2020 Jun 26;99(26):e20686
pubmed: 32590742
ERJ Open Res. 2021 Feb 07;8(1):
pubmed: 35141326
N Engl J Med. 1970 Aug 6;283(6):271-6
pubmed: 4193468
Am J Ind Med. 2021 Nov;64(11):915-923
pubmed: 34390259
Respir Med. 2005 Aug;99(8):943-7
pubmed: 15950134
Chest. 2013 Nov;144(5):1644-1651
pubmed: 23828161
Thorax. 2014 Aug;69(8):703-8
pubmed: 24488371
Am J Respir Crit Care Med. 2012 Aug 15;186(4):314-24
pubmed: 22679012
Am J Respir Crit Care Med. 2020 Aug 1;202(3):e36-e69
pubmed: 32706311
Pulmonology. 2019 Mar - Apr;25(2):97-108
pubmed: 30126802
Intern Med. 2002 Dec;41(12):1179-82
pubmed: 12521211
J Investig Allergol Clin Immunol. 2015;25(4):237-50; quiz follow 250
pubmed: 26310038
Ann Am Thorac Soc. 2018 Apr;15(4):460-469
pubmed: 29236517
Clin Rheumatol. 2021 Apr;40(4):1211-1220
pubmed: 32794076

Auteurs

Mike Obregon (M)

Internal Medicine, Southern Illinois University School of Medicine, Springfield, USA.

Saif Faiek (S)

Pulmonology and Critical Care, Southern Illinois University School of Medicine, Springfield, USA.

Peter White (P)

Pulmonology and Critical Care, Southern Illinois University School of Medicine, Springfield, USA.

Classifications MeSH