Proceedings of a membrane update symposium: advancements, scientific insights, and future trends for dialysis membranes for enhanced clinical outcomes in end stage kidney disease patients.

biocompatibility chronic kidney disease clinical impact dialysis membranes innovation science technology

Journal

Frontiers in nephrology
ISSN: 2813-0626
Titre abrégé: Front Nephrol
Pays: Switzerland
ID NLM: 9918469487906676

Informations de publication

Date de publication:
2024
Historique:
received: 26 06 2024
accepted: 04 09 2024
medline: 30 10 2024
pubmed: 30 10 2024
entrez: 30 10 2024
Statut: epublish

Résumé

From September 6 - 8 2022, the Life/2022 Membrane Symposium was held in Frankfurt, Germany, and transmitted live to a worldwide internet audience. The event was part of the Life/Nephrology Campus initiative, a continuous educational platform for the nephrology community to expand knowledge and share expertise on contemporary topics in chronic kidney disease. We describe recent questions and advances in the field, and we underline challenges in the care of dialysis patients and opportunities for integration of new findings into clinical practice to improve patient outcomes in end stage kidney disease patients. Most patients with kidney failure are on maintenance hemodialysis (MHD). The scientific program of the symposium was developed around topics about the role, functional determinants, technical aspects, limitations, and clinical implications of membranes presently in use. International experts with clinical or technical expertise as well as scientific recognition within the nephrology community were asked to prepare their presentations based on their own experiences, perceptions, opinions, and sources of information. The symposium devoted a major portion to discussing novel approaches for improving membranes and treatment quality, including updates on innovative concepts that may could potentially transform the landscape of kidney replacement therapy for chronic kidney disease patients in the future. The intent was to provide insights into current attention points for healthcare professionals new to the field of MHD, and to test a unique forum for continuing medical education integrating physician and patient experiences to promote changes in clinical practice. Furthermore, the symposium premiered a specifically developed mixed reality holographic 3D model to demonstrate recent dialyzer innovation diminishing protein fouling on membrane surfaces. As a continuous online educational platform for scientific exchange, this Life/2022 event provided online learning opportunities with on-demand content, with all symposium lectures freely available on

Identifiants

pubmed: 39473870
doi: 10.3389/fneph.2024.1455260
pmc: PMC11520239
doi:

Types de publication

Journal Article

Langues

eng

Pagination

1455260

Informations de copyright

Copyright © 2024 Wanner, Vanholder, Ortiz, Davenport, Canaud, Blankestijn, Masereeuw, Kooman, Castellano, Stamatialis, Mitra, Grooteman, Weber, Ebert, Abdelrasoul, Steppan, Scheiwe and Stenvinkel.

Déclaration de conflit d'intérêts

AO has received grants from Sanofi and consultancy or speaker fees or travel support from Adviccene, Alexion, Astellas, Astrazeneca, Amicus, Amgen, Bioporto, Boehringer Ingelheim, Esteve, Fresenius Medical Care, GSK, Bayer, Sanofi-Genzyme, Sobi, Menarini, Mundipharma, Kyowa Kirin, Lilly, Freeline, Idorsia, Chiesi, Otsuka, Novo-Nordisk, Sysmex and Vifor Fresenius Medical Care Renal Pharma and Spafarma and is Director of the Catedra UAM-Astrazeneca of chronic kidney disease and electrolytes. He has stock in Telara Farma. Authors SS and AS were employed by Fresenius SE & Co. KGaA. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Christoph Wanner (C)

Renal Research Unit, Department of Clinical Research and Epidemiology, University of Würzburg, Würzburg, Germany.
Clinical Trial Service and Epidemiology Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.

Raymond Vanholder (R)

Nephrology Section, Department of Internal Medicine and Pediatrics, University Hospital, Ghent, Belgium.
European Kidney Health Alliance, Brussels, Belgium.

Alberto Ortiz (A)

Department of Nephrology and Hypertension, IIS-Fundacion Jimenez Diaz UAM, Madrid, Spain.
Departamento de Medicina, Facultad de Medicina, Universidad Autónoma de Madrid, Madrid, Spain.

Andrew Davenport (A)

UCL Department of Nephrology, Royal Free Hospital, University College London, London, United Kingdom.

Bernard Canaud (B)

School of Medicine, University of Montpellier, Montpellier, France.

Peter J Blankestijn (PJ)

Department of Nephrology and Hypertension, University Medical Centre Utrecht, Utrecht University, Utrecht, Netherlands.

Rosalinde Masereeuw (R)

Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, Netherlands.

Jeroen Peter Kooman (JP)

Division of Nephrology, Department of Internal Medicine, Maastricht University Medical Centre+, Maastricht, Netherlands.
Department of Internal Medicine, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University, Maastricht, Netherlands.

Giuseppe Castellano (G)

Department of Nephrology, Dialysis and Renal Transplantation, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy.

Dimitrios Stamatialis (D)

Advanced Organ Bioengineering and Therapeutics-Technical Medical Centre, University of Twente, Enschede, Netherlands.
Department of Nephrology, Radboud University Medical Center, Radboud Institute for Molecular Life Sciences, Nijmegen, Netherlands.

Sandip Mitra (S)

Manchester Academy of Health Sciences Centre, Manchester University Hospitals, University of Manchester, Manchester, United Kingdom.

Muriel Grooteman (M)

Department of Nephrology, Amsterdam UMC, location Vrije Universiteit Amsterdam, Nephrology, Amsterdam, Netherlands.
Department of Nephrology, Amsterdam Cardiovascular Sciences, Diabetes & Metabolism, Amsterdam, Netherlands.

Viktoria Weber (V)

Department for Biomedical Research, University for Continuing Education Krems, Krem, Austria.

Thomas Ebert (T)

Medical Department III - Endocrinology, Nephrology, Rheumatology, University of Leipzig Medical Center, Leipzig, Germany.

Amira Abdelrasoul (A)

Division of Biomedical Engineering, Department of Chemical and Biological Engineering, University of Saskatchewan, Saskatoon, SK, Canada.

Sonja Steppan (S)

Fresenius SE & Co. KGaA, Bad Homburg, Germany.

Anna Rebecca Scheiwe (AR)

Fresenius SE & Co. KGaA, Bad Homburg, Germany.

Peter Stenvinkel (P)

Division of Renal Medicine, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden.

Classifications MeSH