Deciphering the killing mechanisms of potassium iodide in combination with antimicrobial photodynamic therapy against cross-kingdom biofilm.
Biofilms
/ drug effects
Potassium Iodide
/ pharmacology
Humans
Photochemotherapy
/ methods
Candida albicans
/ drug effects
Streptococcus mutans
/ drug effects
Reactive Oxygen Species
/ metabolism
Tolonium Chloride
/ pharmacology
Photosensitizing Agents
/ pharmacology
Anti-Infective Agents
/ pharmacology
Microbial Viability
/ drug effects
Dental Caries
/ microbiology
Apoptosis
/ drug effects
Dentin
/ microbiology
Candida albicans
Streptococcus mutans
antimicrobial mechanism
antimicrobial photodynamic therapy
cross-kingdom biofilm
potassium iodide
Journal
Frontiers in cellular and infection microbiology
ISSN: 2235-2988
Titre abrégé: Front Cell Infect Microbiol
Pays: Switzerland
ID NLM: 101585359
Informations de publication
Date de publication:
2024
2024
Historique:
received:
06
06
2024
accepted:
25
09
2024
medline:
30
10
2024
pubmed:
30
10
2024
entrez:
30
10
2024
Statut:
epublish
Résumé
The co-existence of Mixed-species biofilm was constructed of KI+TBO-aPDT treatment caused reduction in microorganism counts, metabolic activity, and biofilm biomass of mixed-species biofilm without inducing cytotoxicity to hDPCs (human dental pulp cells). Observations such increased ROS (reactive oxygen species) levels, impaired cell membrane function, cell apoptosis and reduced expression in several genes seem to be artifacts of reduced growth and general killing by KI+TBO-aPDT treatment. These data suggested that KI in combination with aPDT as an innovative approach to combat
Identifiants
pubmed: 39473923
doi: 10.3389/fcimb.2024.1444764
pmc: PMC11518841
doi:
Substances chimiques
Potassium Iodide
1C4QK22F9J
Reactive Oxygen Species
0
Tolonium Chloride
15XUH0X66N
Photosensitizing Agents
0
Anti-Infective Agents
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1444764Informations de copyright
Copyright © 2024 Li, Huang, Du, Wang, Cai and Huang.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Références
Biofouling. 2017 Sep;33(8):661-675
pubmed: 28792234
Cell. 2007 Sep 7;130(5):797-810
pubmed: 17803904
Photobiomodul Photomed Laser Surg. 2020 Aug;38(8):481-496
pubmed: 32716697
Minerva Stomatol. 2012 Sep;61(9):399-419
pubmed: 22976567
Med Mycol. 2007 Jun;45(4):363-70
pubmed: 17510860
Lasers Med Sci. 2016 Jul;31(5):997-1009
pubmed: 27126412
Oral Microbiol Immunol. 2007 Feb;22(1):30-5
pubmed: 17241168
Front Cell Infect Microbiol. 2023 May 11;13:1106231
pubmed: 37249973
J Biophotonics. 2024 Mar;17(3):e202300332
pubmed: 38041248
Front Microbiol. 2018 Nov 30;9:2983
pubmed: 30555455
Appl Environ Microbiol. 2013 Mar;79(5):1436-43
pubmed: 23263955
Eukaryot Cell. 2006 Oct;5(10):1604-10
pubmed: 17030992
ISME J. 2018 Jun;12(6):1427-1442
pubmed: 29670217
Mol Oral Microbiol. 2021 Aug;36(4):233-242
pubmed: 33977670
Front Pharmacol. 2021 Nov 19;12:760768
pubmed: 34867378
Microb Pathog. 2015 Oct;87:21-9
pubmed: 26169236
BMC Oral Health. 2022 Apr 12;22(1):121
pubmed: 35413908
PLoS Pathog. 2012 Feb;8(2):e1002525
pubmed: 22359502
J Dent Res. 2017 Sep;96(10):1129-1135
pubmed: 28605597
ACS Nano. 2021 Dec 28;15(12):19888-19904
pubmed: 34878250
Caries Res. 2012;46(6):549-54
pubmed: 22922473
BMC Res Notes. 2013 Jul 15;6:272
pubmed: 23856115
Future Med Chem. 2014 Feb;6(2):141-64
pubmed: 24467241
Crit Rev Microbiol. 2018 Sep;44(5):571-589
pubmed: 29749263
J Oral Microbiol. 2019 Mar 20;11(1):1581520
pubmed: 31681463
Front Microbiol. 2016 Feb 10;7:140
pubmed: 26904013
Antimicrob Agents Chemother. 2015 Sep;59(9):5203-12
pubmed: 26077247
Biofouling. 2014;30(5):579-88
pubmed: 24730462
Front Cell Infect Microbiol. 2022 Mar 22;12:872012
pubmed: 35392605
Am J Infect Control. 2002 Dec;30(8):S1-46
pubmed: 12461507
Biofouling. 2018 Nov;34(10):1175-1184
pubmed: 30744421
Front Microbiol. 2017 Jun 08;8:1036
pubmed: 28642749
Arch Oral Biol. 2006 Nov;51(11):1024-8
pubmed: 16890907
Oral Microbiol Immunol. 2007 Oct;22(5):289-92
pubmed: 17803624
J Dent Res. 2018 Dec;97(13):1468-1476
pubmed: 30049240
Lasers Med Sci. 2015 Feb;30(2):685-94
pubmed: 23912779
Mol Oral Microbiol. 2022 Oct;37(5):218-228
pubmed: 35859523
Sci Rep. 2021 May 24;11(1):10802
pubmed: 34031498
Int J Mol Sci. 2022 Sep 27;23(19):
pubmed: 36232675
Crit Rev Microbiol. 2020 Aug;46(4):475-491
pubmed: 32720594
ISME J. 2021 Mar;15(3):894-908
pubmed: 33149208
Appl Microbiol Biotechnol. 2020 Dec;104(24):10711-10724
pubmed: 33170329