Concurrent predictors of behavioral inflexibility in minimally verbal and verbal autistic children.

anxiety autism behavioral inflexibility mental health minimally verbal

Journal

Autism research : official journal of the International Society for Autism Research
ISSN: 1939-3806
Titre abrégé: Autism Res
Pays: United States
ID NLM: 101461858

Informations de publication

Date de publication:
30 Oct 2024
Historique:
received: 05 04 2024
accepted: 11 10 2024
medline: 30 10 2024
pubmed: 30 10 2024
entrez: 30 10 2024
Statut: aheadofprint

Résumé

Behavioral inflexibility (BI) refers to the rigid and inflexible patterns of behaviors that are a core aspect of autism. Few studies have investigated BI in autism separately from other restricted and repetitive behaviors (RRBs). The present study used a relatively new measure, the behavioral inflexibility scale (BIS; Lecavalier, L., Bodfish, J., Harrop, C., Whitten, A., Jones, D., Pritchett, J., Faldowski, R., & Boyd, B. (2020). Autism Research, 13(3), 489-499), to examine the relationship of BI and variables that are both core symptoms in autism as well as symptoms associated with cooccurring mental health conditions, atypical sensory experiences, and adaptive functioning in a sample of 87 children with autism. Additionally, we aimed to understand how these relationships may be related to autistic individuals' verbal status: minimally verbal (MV) or verbal. Results revealed that anxiety, attention deficit/hyperactive, depressive, oppositional defiance problems, and sensory differences were all significantly correlated with BI in the MV group. In contrast, only anxiety, depressive, and oppositional defiance problems were significantly correlated with BI in the verbal group. Linear regression analyses showed that oppositional defiance problems and atypical sensory experiences explained a significant proportion of the variance of BI in the MV group, whereas only depressive problems were significant in the verbal group after accounting for other mental health conditions. Overall, our findings demonstrate that multiple aspects of psychopathology are significantly related to BI and can have broader implications for interventions and mental health care in autistic children.

Identifiants

pubmed: 39474671
doi: 10.1002/aur.3251
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : NIDCD NIH HHS
Pays : United States

Informations de copyright

© 2024 International Society for Autism Research and Wiley Periodicals LLC.

Références

American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders: DSM‐5 (Vol. 5). American psychiatric association.
Baranek, G. T., David, F. J., Poe, M. D., Stone, W. L., & Watson, L. R. (2006). Sensory experiences questionnaire: Discriminating sensory features in young children with autism, developmental delays, and typical development. Journal of Child Psychology and Psychiatry, 47(6), 591–601.
Benjamini, Y., & Hochberg, Y. (1995). Controlling the false discovery rate: A practical and powerful approach to multiple testing. Journal of the Royal Statistical Society: Series B (Methodological), 57(1), 289–300.
Bodfish, J. W., Symons, F. J., Parker, D. E., & Lewis, M. H. (2000). Varieties of repetitive behavior in autism: Comparisons to mental retardation. Journal of Autism and Developmental Disorders, 30, 237–243.
Boyd, B. A., Baranek, G. T., Sideris, J., Poe, M. D., Watson, L. R., Patten, E., & Miller, H. (2010). Sensory features and repetitive behaviors in children with autism and developmental delays. Autism Research, 3(2), 78–87.
Boyd, B. A., McBee, M., Holtzclaw, T., Baranek, G. T., & Bodfish, J. W. (2009). Relationships among repetitive behaviors, sensory features, and executive functions in high functioning autism. Research in Autism Spectrum Disorders, 3(4), 959–966.
Bradshaw, J., Gillespie, S., Klaiman, C., Klin, A., & Saulnier, C. (2019). Early emergence of discrepancy in adaptive behavior and cognitive skills in toddlers with autism spectrum disorder. Autism, 23(6), 1485–1496.
Butler, L. K., la Valle, C., Schwartz, S., Palana, J. B., Liu, C., Peterman, N., Shen, L., & Tager‐Flusberg, H. (2022). Remote natural language sampling of parents and children with autism spectrum disorder: Role of activity and language level. Frontiers in Communication, 7, 820564.
Chatham, C. H., Taylor, K. I., Charman, T., Liogier D'Ardhuy, X., Eule, E., Fedele, A., Hardan, A. Y., Loth, E., Murtagh, L., del Valle Rubido, M., San Jose Caceres, A., Sevigny, J., Sikich, L., Snyder, L., Tillmann, J. E., Ventola, P. E., Walton‐Bowen, K. L., Wang, P. P., Willgoss, T., & Bolognani, F. (2018). Adaptive behavior in autism: Minimal clinically important differences on the Vineland‐II. Autism Research, 11(2), 270–283.
Chen, Y., Hantman, R., & Tager‐Flusberg, H. (2023). Parent‐rated anxiety in autistic adolescents and young adults: Concurrent links to autism traits and chronic sleep problems. Research in Autism Spectrum Disorders, 101, 102104. https://doi.org/10.1016/j.rasd.2023.102104
Dunn, W. (1999). Short sensory profile. Pearson.
Feldman, J. I., Cassidy, M., Liu, Y., Kirby, A. V., Wallace, M. T., & Woynaroski, T. G. (2020). Relations between sensory responsiveness and features of autism in children. Brain Sciences, 10(11), 775.
Frost, K. M., Hong, N., & Lord, C. (2017). Correlates of adaptive functioning in minimally verbal children with autism spectrum disorder. American Journal on Intellectual and Developmental Disabilities, 122(1), 1–10. https://doi.org/10.1352/1944-7558-122.1.1
Gabriels, R. L., Agnew, J. A., Miller, L. J., Gralla, J., Pan, Z., Goldson, E., Ledbetter, J. C., Dinkins, J. P., & Hooks, E. (2008). Is there a relationship between restricted, repetitive, stereotyped behaviors and interests and abnormal sensory response in children with autism spectrum disorders? Research in Autism Spectrum Disorders, 2(4), 660–670.
Goldberg, D. (2012). The overlap between the common mental disorders—Challenges for classification. International Review of Psychiatry, 24(6), 549–555.
Harris, P. A., Taylor, R., Thielke, R., Payne, J., Gonzalez, N., & Conde, J. G. (2009). Research electronic data capture (REDCap)—A metadata‐driven methodology and workflow process for providing translational research informatics support. Journal of Biomedical Informatics, 42(2), 377–381.
Harrop, C., Bodfish, J., Lecavalier, L., Dallman, A. R., Jones, D., Pritchett, J., Whitten, A., & Boyd, B. A. (2024). Refining our understanding of anxiety in autistic youth: Examining the role of behavioral inflexibility. Journal of Autism and Developmental Disorders, 54(10), 3620–3629.
Haynes, P. L., Gengler, D., & Kelly, M. (2016). Social rhythm therapies for mood disorders: An update. Current Psychiatry Reports, 18, 1–8.
Jasim, S., & Perry, A. (2023). Repetitive and restricted behaviors and interests in autism spectrum disorder: Relation to individual characteristics and mental health problems. BMC Psychiatry, 23(1), 1–14.
Kanner, L. (1943). Autistic disturbances of affective contact. Nervous Child, 2(3), 217–250.
Kerns, C. M., Rast, J. E., & Shattuck, P. T. (2020). Prevalence and correlates of caregiver‐reported mental health conditions in youth with autism spectrum disorder in the United States. The Journal of Clinical Psychiatry, 82(1), 11637.
Lecavalier, L., Bodfish, J., Harrop, C., Whitten, A., Jones, D., Pritchett, J., Faldowski, R., & Boyd, B. (2020). Development of the behavioral inflexibility scale for children with autism spectrum disorder and other developmental disabilities. Autism Research, 13(3), 489–499.
Lerner, M. D., Mazefsky, C. A., Weber, R. J., Transue, E., Siegel, M., & Gadow, K. D. (2018). Verbal ability and psychiatric symptoms in clinically referred inpatient and outpatient youth with ASD. Journal of Autism and Developmental Disorders, 48, 3689–3701.
Lidstone, J., Uljarević, M., Sullivan, J., Rodgers, J., McConachie, H., Freeston, M., le Couteur, A., Prior, M., & Leekam, S. (2014). Relations among restricted and repetitive behaviors, anxiety and sensory features in children with autism spectrum disorders. Research in Autism Spectrum Disorders, 8(2), 82–92.
McQuaid, G. A., Pelphrey, K. A., Bookheimer, S. Y., Dapretto, M., Webb, S. J., Bernier, R. A., McPartland, J. C., van Horn, J. D., & Wallace, G. L. (2021). The gap between IQ and adaptive functioning in autism spectrum disorder: Disentangling diagnostic and sex differences. Autism, 25(6), 1565–1579.
Miller, J., & Iglesias, A. (2012). Systematic analysis of language transcripts (SALT), research version 2012 [computer software]. Salt Software, LLC.
Moody, E. J., Reyes, N., Ledbetter, C., Wiggins, L., DiGuiseppi, C., Alexander, A., Jackson, S., Lee, L.‐C., Levy, S. E., & Rosenberg, S. A. (2017). Screening for autism with the SRS and SCQ: Variations across demographic, developmental and behavioral factors in preschool children. Journal of Autism and Developmental Disorders, 47, 3550–3561.
Mullen, S. (2018). Major depressive disorder in children and adolescents. Mental Health Clinician, 8(6), 275–283.
Neil, L., Olsson, N. C., & Pellicano, E. (2016). The relationship between intolerance of uncertainty, sensory sensitivities, and anxiety in autistic and typically developing children. Journal of Autism and Developmental Disorders, 46, 1962–1973.
Pandolfi, V., Magyar, C. I., & Dill, C. A. (2009). Confirmatory factor analysis of the child behavior checklist 1.5–5 in a sample of children with autism spectrum disorders. Journal of Autism and Developmental Disorders, 39(7), 986–995.
Patten, E., Ausderau, K. K., Watson, L. R., & Baranek, G. T. (2013). Sensory response patterns in nonverbal children with ASD. Autism Research and Treatment, 2013, 436286.
Plesa Skwerer, D., Joseph, R. M., Eggleston, B., & Tager‐Flusberg, H. (2019). Prevalence and correlates of psychiatric symptoms in minimally verbal children and adolescents with ASD. Frontiers in Psychiatry, 10, 417873.
Rispoli, M., Lang, R., Neely, L., Camargo, S., Hutchins, N., Davenport, K., & Goodwyn, F. (2013). A comparison of within‐and across‐activity choices for reducing challenging behavior in children with autism spectrum disorders. Journal of Behavioral Education, 22, 66–83.
Rutter, M., Bailey, A., & Lord, C. (2003). Social communication questionnaire (SCQ). Western Psychological Services.
Scahill, L., Lecavalier, L., Schultz, R. T., Evans, A. N., Maddox, B., Pritchett, J., Herrington, J., Gillespie, S., Miller, J., Amoss, R. T., Aman, M. G., Bearss, K., Gadow, K., & Edwards, M. C. (2019). Development of the parent‐rated anxiety scale for youth with autism spectrum disorder. Journal of the American Academy of Child & Adolescent Psychiatry, 58(9), 887–896.
Schulz, S. E., & Stevenson, R. A. (2019). Sensory hypersensitivity predicts repetitive behaviours in autistic and typically‐developing children. Autism, 23(4), 1028–1041.
Song, D. Y., Kim, D., Lee, H. J., Bong, G., Han, J. H., & Yoo, H. J. (2022). Patterns of restricted and repetitive behaviors in toddlers and young children with autism spectrum disorder. Journal of the Korean Academy of Child and Adolescent Psychiatry, 33(2), 35–40.
Spackman, E., Smillie, L. D., Frazier, T. W., Hardan, A. Y., & Uljarević, M. (2023). Characterizing subdomains of insistence on sameness in autistic youth. Autism Research, 16(12), 2326–2335.
Sparrow, S. S., Cicchetti, D. V., & Saulnier, C. A. (2016). Vineland adaptive behavior scales: Third edition (Vineland‐3). Pearson.
Stratis, E. A., & Lecavalier, L. (2013). Restricted and repetitive behaviors and psychiatric symptoms in youth with autism spectrum disorders. Research in Autism Spectrum Disorders, 7(6), 757–766.
Tillmann, J., San José Cáceres, A., Chatham, C. H., Crawley, D., Holt, R., Oakley, B., Banaschewski, T., Baron‐Cohen, S., Bölte, S., Buitelaar, J. K., Durston, S., Ham, L., Loth, E., Simonoff, E., Spooren, W., Murphy, D. G., Charman, T., & Group, E. U.‐A. I. M. S. L. E. A. P. (2019). Investigating the factors underlying adaptive functioning in autism in the EU‐AIMS longitudinal European autism project. Autism Research, 12(4), 645–657.
Tomchek, S. D., & Dunn, W. (2007). Sensory processing in children with and without autism: A comparative study using the short sensory profile. The American Journal of Occupational Therapy, 61(2), 190–200. https://doi.org/10.5014/ajot.61.2.190
Troyb, E., Knoch, K., Herlihy, L., Stevens, M. C., Chen, C. M., Barton, M., Treadwell, K., & Fein, D. (2016). Restricted and repetitive behaviors as predictors of outcome in autism spectrum disorders. Journal of Autism and Developmental Disorders, 46(4), 1282–1296. https://doi.org/10.1007/s10803-015-2668-2
Uljarević, M., Frazier, T. W., Jo, B., Billingham, W. D., Cooper, M. N., Youngstrom, E. A., Scahill, L., & Hardan, A. Y. (2022). Big data approach to characterize restricted and repetitive behaviors in autism. Journal of the American Academy of Child & Adolescent Psychiatry, 61(3), 446–457.
Uljarević, M., Richdale, A. L., Evans, D. W., Cai, R. Y., & Leekam, S. R. (2017). Interrelationship between insistence on sameness, effortful control and anxiety in adolescents and young adults with autism spectrum disorder (ASD). Molecular Autism, 8, 1–6.
Watson, L. R., Patten, E., Baranek, G. T., Poe, M., Boyd, B. A., Freuler, A., & Lorenzi, J. (2011). Differential associations between sensory response patterns and language, social, and communication measures in children with autism or other developmental disabilities. Journal of Speech, Language, and Hearing Research, 54, 1562–1576.

Auteurs

Charlotte Gaynor (C)

Department of Psychological and Brain Sciences, Boston University, Boston, Massachusetts, USA.

Yanru Chen (Y)

Department of Psychological and Brain Sciences, Boston University, Boston, Massachusetts, USA.

Helen Tager-Flusberg (H)

Department of Psychological and Brain Sciences, Boston University, Boston, Massachusetts, USA.

Classifications MeSH