A prediction model for differential resilience to the effects of combat-related stressors in US army soldiers.


Journal

International journal of methods in psychiatric research
ISSN: 1557-0657
Titre abrégé: Int J Methods Psychiatr Res
Pays: United States
ID NLM: 9111433

Informations de publication

Date de publication:
Dec 2024
Historique:
received: 01 10 2024
accepted: 13 10 2024
medline: 30 10 2024
pubmed: 30 10 2024
entrez: 30 10 2024
Statut: ppublish

Résumé

To develop a composite score for differential resilience to effects of combat-related stressors (CRS) on persistent DSM-IV post-traumatic stress disorder (PTSD) among US Army combat arms soldiers using survey data collected before deployment. A sample of n = 2542 US Army combat arms soldiers completed a survey shortly before deployment to Afghanistan and then again two to three and 8-9 months after redeployment. Retrospective self-reports were obtained about CRS. Precision treatment methods were used to determine whether differential resilience to persistent PTSD in the follow-up surveys could be developed from pre-deployment survey data in a 60% training sample and validated in a 40% test sample. 40.8% of respondents experienced high CRS and 5.4% developed persistent PTSD. Significant test sample heterogeneity was found in resilience (t = 2.1, p = 0.032), with average treatment effect (ATE) of high CRS in the 20% least resilient soldiers of 17.1% (SE = 5.5%) compared to ATE = 3.8% (SE = 1.2%) in the remaining 80%. The most important predictors involved recent and lifetime pre-deployment distress disorders. A reliable pre-deployment resilience score can be constructed to predict variation in the effects of high CRS on persistent PTSD among combat arms soldiers. Such a score could be used to target preventive interventions to reduce PTSD or other resilience-related outcomes.

Identifiants

pubmed: 39475323
doi: 10.1002/mpr.70006
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e70006

Subventions

Organisme : NIMH NIH HHS
ID : U01MH087981
Pays : United States
Organisme : U.S. Department of Defense
ID : HU0001-15-2-0004
Organisme : U.S. Army
ID : U01MH087981

Informations de copyright

© 2024 The Author(s). International Journal of Methods in Psychiatric Research published by John Wiley & Sons Ltd.

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Auteurs

Ronald C Kessler (RC)

Department of Health Care Policy, Harvard Medical School, Boston, Massachusetts, USA.

Robert M Bossarte (RM)

Department of Psychiatry and Behavioral Neuroscience, Morsani School of Medicine Tampa, University of South Florida, Tampa, Florida, USA.
Center for Mental Health Outcomes Research, Central Arkansas VA Medical Center, North Little Rock, Arkansas, USA.

Irving Hwang (I)

Department of Health Care Policy, Harvard Medical School, Boston, Massachusetts, USA.

Alex Luedtke (A)

Department of Statistics, University of Washington, Seattle, Washington, USA.
Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.

James A Naifeh (JA)

Department of Psychiatry, Center for the Study of Traumatic Stress, Uniformed Services University School of Medicine, Bethesda, Maryland, USA.

Matthew K Nock (MK)

Department of Psychology, Harvard University, Cambridge, Massachusetts, USA.

Maria Petukhova (M)

Department of Health Care Policy, Harvard Medical School, Boston, Massachusetts, USA.

Ekaterina Sadikova (E)

Department of Health Care Policy, Harvard Medical School, Boston, Massachusetts, USA.
Department of Social and Behavioral Sciences, Harvard Chan School of Public Health, Boston, Massachusetts, USA.

Nancy A Sampson (NA)

Department of Health Care Policy, Harvard Medical School, Boston, Massachusetts, USA.

Erik Sverdrup (E)

Department of Econometrics & Business Statistics, Monash University, Melbourne, Victoria, Australia.

Jose R Zubizarreta (JR)

Department of Health Care Policy, Harvard Medical School, Boston, Massachusetts, USA.

Stefan Wager (S)

Graduate School of Business, Stanford University, Stanford, California, USA.

James Wagner (J)

Survey Research Center, Institute for Social Research, University of Michigan-Ann Arbor, Ann Arbor, Michigan, USA.

Murray B Stein (MB)

Departments of Psychiatry and Family Medicine and Public Health, University of California San Diego, La Jolla, California, USA.

Robert J Ursano (RJ)

Department of Psychiatry, Center for the Study of Traumatic Stress, Uniformed Services University School of Medicine, Bethesda, Maryland, USA.

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