A genetically encoded actuator boosts L-type calcium channel function in diverse physiological settings.

Calcium Channels, L-Type / metabolism Animals Myocytes, Cardiac / metabolism Humans Calcium / metabolism Mice Neurons / metabolism HEK293 Cells

Journal

Science advances
ISSN: 2375-2548
Titre abrégé: Sci Adv
Pays: United States
ID NLM: 101653440

Informations de publication

Date de publication:
Nov 2024
Historique:
medline: 31 10 2024
pubmed: 30 10 2024
entrez: 30 10 2024
Statut: ppublish

Résumé

L-type Ca

Identifiants

DOI: 10.1126/sciadv.adq3374 PMID: 39475605
pubmed: 39475605
doi: 10.1126/sciadv.adq3374
doi:

Substances chimiques

Calcium Channels, L-Type 0
Calcium SY7Q814VUP

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

eadq3374

Auteurs

Pedro J Del Rivero Morfin (PJ)

Department of Physiology and Cellular Biophysics, Columbia University, New York, NY, USA.
ORCID: 0000-0002-8554-145X

Diego Scala Chavez (DS)

Pediatric Neurology, Department of Pediatrics, Weill Cornell Medicine, New York, NY, USA.

Srinidhi Jayaraman (S)

Department of Physiology and Cellular Biophysics, Columbia University, New York, NY, USA.

Lin Yang (L)

Division of Cardiology, Department of Medicine, Columbia University, Vagelos College of Physicians and Surgeons, New York, NY, USA.

Stefanie M Geisler (SM)

Department of Pharmacology and Toxicology, University of Innsbruck, Innsbruck, Tyrol, Austria.
ORCID: 0000-0002-8898-0108

Audrey L Kochiss (AL)

Department of Physiology and Cellular Biophysics, Columbia University, New York, NY, USA.

Petronel Tuluc (P)

Department of Pharmacology and Toxicology, University of Innsbruck, Innsbruck, Tyrol, Austria.
ORCID: 0000-0003-3660-6138

Henry M Colecraft (HM)

Department of Physiology and Cellular Biophysics, Columbia University, New York, NY, USA.
Department of Molecular Pharmacology and Therapeutics, Columbia University, New York, NY, USA.
ORCID: 0000-0002-2340-8899

Steven O Marx (SO)

Division of Cardiology, Department of Medicine, Columbia University, Vagelos College of Physicians and Surgeons, New York, NY, USA.
Department of Molecular Pharmacology and Therapeutics, Columbia University, New York, NY, USA.

X Shawn Liu (XS)

Department of Physiology and Cellular Biophysics, Columbia University, New York, NY, USA.
Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, NY, USA.
ORCID: 0000-0002-2799-2519

Anjali M Rajadhyaksha (AM)

Pediatric Neurology, Department of Pediatrics, Weill Cornell Medicine, New York, NY, USA.
Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY, USA.
Weill Cornell Autism Research Program, Weill Cornell Medicine, New York, NY, USA.
ORCID: 0000-0002-8399-5466

Manu Ben-Johny (M)

Department of Physiology and Cellular Biophysics, Columbia University, New York, NY, USA.
ORCID: 0000-0002-5645-0815

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Classifications MeSH

questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Protéines de transport membranaire › Canaux ioniques › Canaux calciques › Canaux calciques de type L › A genetically encoded actuator boosts L-type...
questionsmedicales.fr › Eucaryotes › Animaux › A genetically encoded actuator boosts L-type...
questionsmedicales.fr › Cellules › Cellules musculaires › Myocytes cardiaques › A genetically encoded actuator boosts L-type...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › A genetically encoded actuator boosts L-type...
questionsmedicales.fr › Facteurs biologiques › Facteurs de la coagulation sanguine › Calcium › A genetically encoded actuator boosts L-type...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › A genetically encoded actuator boosts L-type...
questionsmedicales.fr › Cellules › Neurones › A genetically encoded actuator boosts L-type...
questionsmedicales.fr › Cellules › Cellules épithéliales › Cellules HEK293 › A genetically encoded actuator boosts L-type...