Total Hip Replacement or Resistance Training for Severe Hip Osteoarthritis.

Aged Female Humans Male Middle Aged Arthroplasty, Replacement, Hip / statistics & numerical data Intention to Treat Analysis Osteoarthritis, Hip / complications Pain Measurement Resistance Training / statistics & numerical data Arthralgia / diagnosis

Journal

The New England journal of medicine
ISSN: 1533-4406
Titre abrégé: N Engl J Med
Pays: United States
ID NLM: 0255562

Informations de publication

Date de publication:
31 Oct 2024
Historique:
medline: 31 10 2024
pubmed: 30 10 2024
entrez: 30 10 2024
Statut: ppublish

Résumé

Total hip replacement is routinely recommended for severe hip osteoarthritis, but data from randomized trials are lacking regarding comparison of the effectiveness of this procedure with that of nonsurgical treatment such as resistance training. We conducted a multicenter, randomized, controlled trial to compare total hip replacement with resistance training in patients 50 years of age or older who had severe hip osteoarthritis and an indication for surgery. The primary outcome was the change in patient-reported hip pain and function from baseline to 6 months after the initiation of treatment, assessed with the use of the Oxford Hip Score (range, 0 to 48, with higher scores indicating less pain and better function). Safety was also assessed. A total of 109 patients (mean age, 67.6 years) were randomly assigned to total hip replacement (53 patients) or resistance training (56 patients). In an intention-to-treat analysis, the mean increase (indicating improvement) in the Oxford Hip Score was 15.9 points in patients assigned to total hip replacement and 4.5 points in patients assigned to resistance training (difference, 11.4 points; 95% confidence interval, 8.9 to 14.0; P<0.001). At 6 months, 5 patients (9%) who had been assigned to total hip replacement had not undergone surgery, and 12 patients (21%) who had been assigned to resistance training had undergone total hip replacement. The incidence of serious adverse events at 6 months was similar in the two groups; the majority of such events were known complications of total hip replacement. In patients 50 years of age or older who had severe hip osteoarthritis and an indication for surgery, total hip replacement resulted in a clinically important, superior reduction in hip pain and improved hip function, as reported by patients, at 6 months as compared with resistance training. (Funded by the Danish Rheumatism Association and others; PROHIP ClinicalTrials.gov number, NCT04070027.).

Sections du résumé

BACKGROUND BACKGROUND
Total hip replacement is routinely recommended for severe hip osteoarthritis, but data from randomized trials are lacking regarding comparison of the effectiveness of this procedure with that of nonsurgical treatment such as resistance training.
METHODS METHODS
We conducted a multicenter, randomized, controlled trial to compare total hip replacement with resistance training in patients 50 years of age or older who had severe hip osteoarthritis and an indication for surgery. The primary outcome was the change in patient-reported hip pain and function from baseline to 6 months after the initiation of treatment, assessed with the use of the Oxford Hip Score (range, 0 to 48, with higher scores indicating less pain and better function). Safety was also assessed.
RESULTS RESULTS
A total of 109 patients (mean age, 67.6 years) were randomly assigned to total hip replacement (53 patients) or resistance training (56 patients). In an intention-to-treat analysis, the mean increase (indicating improvement) in the Oxford Hip Score was 15.9 points in patients assigned to total hip replacement and 4.5 points in patients assigned to resistance training (difference, 11.4 points; 95% confidence interval, 8.9 to 14.0; P<0.001). At 6 months, 5 patients (9%) who had been assigned to total hip replacement had not undergone surgery, and 12 patients (21%) who had been assigned to resistance training had undergone total hip replacement. The incidence of serious adverse events at 6 months was similar in the two groups; the majority of such events were known complications of total hip replacement.
CONCLUSIONS CONCLUSIONS
In patients 50 years of age or older who had severe hip osteoarthritis and an indication for surgery, total hip replacement resulted in a clinically important, superior reduction in hip pain and improved hip function, as reported by patients, at 6 months as compared with resistance training. (Funded by the Danish Rheumatism Association and others; PROHIP ClinicalTrials.gov number, NCT04070027.).

Identifiants

DOI: 10.1056/NEJMoa2400141 PMID: 39476341
pubmed: 39476341
doi: 10.1056/NEJMoa2400141
doi:

Banques de données

ClinicalTrials.gov
['NCT04070027']

Types de publication

Journal Article Multicenter Study Randomized Controlled Trial Comparative Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

1610-1620

Subventions

Organisme : Region Sjælland
ID : R23-A786
Organisme : Gigtforeningen
ID : R153-A4771
Organisme : Gigtforeningen
ID : R161-A5280
Organisme : Gigtforeningen
ID : R166-A5553
Organisme : Gigtforeningen
ID : R176-A6231
Organisme : Næstved Sygehus
ID : N/A
Organisme : Region Syddanmark
ID : 17/33622
Organisme : Region Syddanmark
ID : 18/41994
Organisme : Fonden til Lægevidenskabens Fremme
ID : N/A
Organisme : Danske Fysioterapeuter
ID : N/A

Informations de copyright

Copyright © 2024 Massachusetts Medical Society.

Auteurs

Thomas Frydendal (T)

From the Departments of Physiotherapy (T.F., K.G.I.) and Orthopedic Surgery (C.V., A.E.G., P.K.-A., P.H.R., C.H.), Lillebaelt Hospital-University Hospital of Southern Denmark, Vejle Hospital, Vejle, the Departments of Clinical Research (T.F., R.C., S.M.N.) and Regional Health Research (C.V., K.G.I.), University of Southern Denmark, and the Research Unit of Rheumatology, Department of Clinical Research (R.C., S.M.N.), and the Department of Orthopedic Surgery and Traumatology (S.O.), Odense University Hospital, Odense, the Section for Biostatistics and Evidence-based Research, Parker Institute, Bispebjerg and Frederiksberg Hospital (T.F., R.C., S.M.N., K.G.I.), the Department of Orthopedic Surgery and Traumatology, Copenhagen University Hospital Bispebjerg (S.O.), and the Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen (S.O.), Copenhagen, the Department of Orthopedic Surgery, Aarhus University Hospital, and the Department of Clinical Medicine, Aarhus University, Aarhus (I.M., S.S.J.), the University Clinic for Orthopedic Pathways, Elective Surgery Center, Regional Hospital Silkeborg, Silkeborg (L.R.M.), and the Department of Orthopedic Surgery, Næstved Hospital, Næstved (M.J.B., H.Q., M.S.M.) - all in Denmark.
ORCID: 0000-0002-4060-3792

Robin Christensen (R)

From the Departments of Physiotherapy (T.F., K.G.I.) and Orthopedic Surgery (C.V., A.E.G., P.K.-A., P.H.R., C.H.), Lillebaelt Hospital-University Hospital of Southern Denmark, Vejle Hospital, Vejle, the Departments of Clinical Research (T.F., R.C., S.M.N.) and Regional Health Research (C.V., K.G.I.), University of Southern Denmark, and the Research Unit of Rheumatology, Department of Clinical Research (R.C., S.M.N.), and the Department of Orthopedic Surgery and Traumatology (S.O.), Odense University Hospital, Odense, the Section for Biostatistics and Evidence-based Research, Parker Institute, Bispebjerg and Frederiksberg Hospital (T.F., R.C., S.M.N., K.G.I.), the Department of Orthopedic Surgery and Traumatology, Copenhagen University Hospital Bispebjerg (S.O.), and the Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen (S.O.), Copenhagen, the Department of Orthopedic Surgery, Aarhus University Hospital, and the Department of Clinical Medicine, Aarhus University, Aarhus (I.M., S.S.J.), the University Clinic for Orthopedic Pathways, Elective Surgery Center, Regional Hospital Silkeborg, Silkeborg (L.R.M.), and the Department of Orthopedic Surgery, Næstved Hospital, Næstved (M.J.B., H.Q., M.S.M.) - all in Denmark.
ORCID: 0000-0002-6600-0631

Inger Mechlenburg (I)

From the Departments of Physiotherapy (T.F., K.G.I.) and Orthopedic Surgery (C.V., A.E.G., P.K.-A., P.H.R., C.H.), Lillebaelt Hospital-University Hospital of Southern Denmark, Vejle Hospital, Vejle, the Departments of Clinical Research (T.F., R.C., S.M.N.) and Regional Health Research (C.V., K.G.I.), University of Southern Denmark, and the Research Unit of Rheumatology, Department of Clinical Research (R.C., S.M.N.), and the Department of Orthopedic Surgery and Traumatology (S.O.), Odense University Hospital, Odense, the Section for Biostatistics and Evidence-based Research, Parker Institute, Bispebjerg and Frederiksberg Hospital (T.F., R.C., S.M.N., K.G.I.), the Department of Orthopedic Surgery and Traumatology, Copenhagen University Hospital Bispebjerg (S.O.), and the Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen (S.O.), Copenhagen, the Department of Orthopedic Surgery, Aarhus University Hospital, and the Department of Clinical Medicine, Aarhus University, Aarhus (I.M., S.S.J.), the University Clinic for Orthopedic Pathways, Elective Surgery Center, Regional Hospital Silkeborg, Silkeborg (L.R.M.), and the Department of Orthopedic Surgery, Næstved Hospital, Næstved (M.J.B., H.Q., M.S.M.) - all in Denmark.

Lone R Mikkelsen (LR)

From the Departments of Physiotherapy (T.F., K.G.I.) and Orthopedic Surgery (C.V., A.E.G., P.K.-A., P.H.R., C.H.), Lillebaelt Hospital-University Hospital of Southern Denmark, Vejle Hospital, Vejle, the Departments of Clinical Research (T.F., R.C., S.M.N.) and Regional Health Research (C.V., K.G.I.), University of Southern Denmark, and the Research Unit of Rheumatology, Department of Clinical Research (R.C., S.M.N.), and the Department of Orthopedic Surgery and Traumatology (S.O.), Odense University Hospital, Odense, the Section for Biostatistics and Evidence-based Research, Parker Institute, Bispebjerg and Frederiksberg Hospital (T.F., R.C., S.M.N., K.G.I.), the Department of Orthopedic Surgery and Traumatology, Copenhagen University Hospital Bispebjerg (S.O.), and the Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen (S.O.), Copenhagen, the Department of Orthopedic Surgery, Aarhus University Hospital, and the Department of Clinical Medicine, Aarhus University, Aarhus (I.M., S.S.J.), the University Clinic for Orthopedic Pathways, Elective Surgery Center, Regional Hospital Silkeborg, Silkeborg (L.R.M.), and the Department of Orthopedic Surgery, Næstved Hospital, Næstved (M.J.B., H.Q., M.S.M.) - all in Denmark.

Claus Varnum (C)

From the Departments of Physiotherapy (T.F., K.G.I.) and Orthopedic Surgery (C.V., A.E.G., P.K.-A., P.H.R., C.H.), Lillebaelt Hospital-University Hospital of Southern Denmark, Vejle Hospital, Vejle, the Departments of Clinical Research (T.F., R.C., S.M.N.) and Regional Health Research (C.V., K.G.I.), University of Southern Denmark, and the Research Unit of Rheumatology, Department of Clinical Research (R.C., S.M.N.), and the Department of Orthopedic Surgery and Traumatology (S.O.), Odense University Hospital, Odense, the Section for Biostatistics and Evidence-based Research, Parker Institute, Bispebjerg and Frederiksberg Hospital (T.F., R.C., S.M.N., K.G.I.), the Department of Orthopedic Surgery and Traumatology, Copenhagen University Hospital Bispebjerg (S.O.), and the Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen (S.O.), Copenhagen, the Department of Orthopedic Surgery, Aarhus University Hospital, and the Department of Clinical Medicine, Aarhus University, Aarhus (I.M., S.S.J.), the University Clinic for Orthopedic Pathways, Elective Surgery Center, Regional Hospital Silkeborg, Silkeborg (L.R.M.), and the Department of Orthopedic Surgery, Næstved Hospital, Næstved (M.J.B., H.Q., M.S.M.) - all in Denmark.

Anders E Graversen (AE)

From the Departments of Physiotherapy (T.F., K.G.I.) and Orthopedic Surgery (C.V., A.E.G., P.K.-A., P.H.R., C.H.), Lillebaelt Hospital-University Hospital of Southern Denmark, Vejle Hospital, Vejle, the Departments of Clinical Research (T.F., R.C., S.M.N.) and Regional Health Research (C.V., K.G.I.), University of Southern Denmark, and the Research Unit of Rheumatology, Department of Clinical Research (R.C., S.M.N.), and the Department of Orthopedic Surgery and Traumatology (S.O.), Odense University Hospital, Odense, the Section for Biostatistics and Evidence-based Research, Parker Institute, Bispebjerg and Frederiksberg Hospital (T.F., R.C., S.M.N., K.G.I.), the Department of Orthopedic Surgery and Traumatology, Copenhagen University Hospital Bispebjerg (S.O.), and the Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen (S.O.), Copenhagen, the Department of Orthopedic Surgery, Aarhus University Hospital, and the Department of Clinical Medicine, Aarhus University, Aarhus (I.M., S.S.J.), the University Clinic for Orthopedic Pathways, Elective Surgery Center, Regional Hospital Silkeborg, Silkeborg (L.R.M.), and the Department of Orthopedic Surgery, Næstved Hospital, Næstved (M.J.B., H.Q., M.S.M.) - all in Denmark.

Per Kjærsgaard-Andersen (P)

From the Departments of Physiotherapy (T.F., K.G.I.) and Orthopedic Surgery (C.V., A.E.G., P.K.-A., P.H.R., C.H.), Lillebaelt Hospital-University Hospital of Southern Denmark, Vejle Hospital, Vejle, the Departments of Clinical Research (T.F., R.C., S.M.N.) and Regional Health Research (C.V., K.G.I.), University of Southern Denmark, and the Research Unit of Rheumatology, Department of Clinical Research (R.C., S.M.N.), and the Department of Orthopedic Surgery and Traumatology (S.O.), Odense University Hospital, Odense, the Section for Biostatistics and Evidence-based Research, Parker Institute, Bispebjerg and Frederiksberg Hospital (T.F., R.C., S.M.N., K.G.I.), the Department of Orthopedic Surgery and Traumatology, Copenhagen University Hospital Bispebjerg (S.O.), and the Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen (S.O.), Copenhagen, the Department of Orthopedic Surgery, Aarhus University Hospital, and the Department of Clinical Medicine, Aarhus University, Aarhus (I.M., S.S.J.), the University Clinic for Orthopedic Pathways, Elective Surgery Center, Regional Hospital Silkeborg, Silkeborg (L.R.M.), and the Department of Orthopedic Surgery, Næstved Hospital, Næstved (M.J.B., H.Q., M.S.M.) - all in Denmark.

Peter H Revald (PH)

From the Departments of Physiotherapy (T.F., K.G.I.) and Orthopedic Surgery (C.V., A.E.G., P.K.-A., P.H.R., C.H.), Lillebaelt Hospital-University Hospital of Southern Denmark, Vejle Hospital, Vejle, the Departments of Clinical Research (T.F., R.C., S.M.N.) and Regional Health Research (C.V., K.G.I.), University of Southern Denmark, and the Research Unit of Rheumatology, Department of Clinical Research (R.C., S.M.N.), and the Department of Orthopedic Surgery and Traumatology (S.O.), Odense University Hospital, Odense, the Section for Biostatistics and Evidence-based Research, Parker Institute, Bispebjerg and Frederiksberg Hospital (T.F., R.C., S.M.N., K.G.I.), the Department of Orthopedic Surgery and Traumatology, Copenhagen University Hospital Bispebjerg (S.O.), and the Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen (S.O.), Copenhagen, the Department of Orthopedic Surgery, Aarhus University Hospital, and the Department of Clinical Medicine, Aarhus University, Aarhus (I.M., S.S.J.), the University Clinic for Orthopedic Pathways, Elective Surgery Center, Regional Hospital Silkeborg, Silkeborg (L.R.M.), and the Department of Orthopedic Surgery, Næstved Hospital, Næstved (M.J.B., H.Q., M.S.M.) - all in Denmark.

Christian Hofbauer (C)

From the Departments of Physiotherapy (T.F., K.G.I.) and Orthopedic Surgery (C.V., A.E.G., P.K.-A., P.H.R., C.H.), Lillebaelt Hospital-University Hospital of Southern Denmark, Vejle Hospital, Vejle, the Departments of Clinical Research (T.F., R.C., S.M.N.) and Regional Health Research (C.V., K.G.I.), University of Southern Denmark, and the Research Unit of Rheumatology, Department of Clinical Research (R.C., S.M.N.), and the Department of Orthopedic Surgery and Traumatology (S.O.), Odense University Hospital, Odense, the Section for Biostatistics and Evidence-based Research, Parker Institute, Bispebjerg and Frederiksberg Hospital (T.F., R.C., S.M.N., K.G.I.), the Department of Orthopedic Surgery and Traumatology, Copenhagen University Hospital Bispebjerg (S.O.), and the Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen (S.O.), Copenhagen, the Department of Orthopedic Surgery, Aarhus University Hospital, and the Department of Clinical Medicine, Aarhus University, Aarhus (I.M., S.S.J.), the University Clinic for Orthopedic Pathways, Elective Surgery Center, Regional Hospital Silkeborg, Silkeborg (L.R.M.), and the Department of Orthopedic Surgery, Næstved Hospital, Næstved (M.J.B., H.Q., M.S.M.) - all in Denmark.

Manuel J Bieder (MJ)

From the Departments of Physiotherapy (T.F., K.G.I.) and Orthopedic Surgery (C.V., A.E.G., P.K.-A., P.H.R., C.H.), Lillebaelt Hospital-University Hospital of Southern Denmark, Vejle Hospital, Vejle, the Departments of Clinical Research (T.F., R.C., S.M.N.) and Regional Health Research (C.V., K.G.I.), University of Southern Denmark, and the Research Unit of Rheumatology, Department of Clinical Research (R.C., S.M.N.), and the Department of Orthopedic Surgery and Traumatology (S.O.), Odense University Hospital, Odense, the Section for Biostatistics and Evidence-based Research, Parker Institute, Bispebjerg and Frederiksberg Hospital (T.F., R.C., S.M.N., K.G.I.), the Department of Orthopedic Surgery and Traumatology, Copenhagen University Hospital Bispebjerg (S.O.), and the Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen (S.O.), Copenhagen, the Department of Orthopedic Surgery, Aarhus University Hospital, and the Department of Clinical Medicine, Aarhus University, Aarhus (I.M., S.S.J.), the University Clinic for Orthopedic Pathways, Elective Surgery Center, Regional Hospital Silkeborg, Silkeborg (L.R.M.), and the Department of Orthopedic Surgery, Næstved Hospital, Næstved (M.J.B., H.Q., M.S.M.) - all in Denmark.

Haidar Qassim (H)

From the Departments of Physiotherapy (T.F., K.G.I.) and Orthopedic Surgery (C.V., A.E.G., P.K.-A., P.H.R., C.H.), Lillebaelt Hospital-University Hospital of Southern Denmark, Vejle Hospital, Vejle, the Departments of Clinical Research (T.F., R.C., S.M.N.) and Regional Health Research (C.V., K.G.I.), University of Southern Denmark, and the Research Unit of Rheumatology, Department of Clinical Research (R.C., S.M.N.), and the Department of Orthopedic Surgery and Traumatology (S.O.), Odense University Hospital, Odense, the Section for Biostatistics and Evidence-based Research, Parker Institute, Bispebjerg and Frederiksberg Hospital (T.F., R.C., S.M.N., K.G.I.), the Department of Orthopedic Surgery and Traumatology, Copenhagen University Hospital Bispebjerg (S.O.), and the Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen (S.O.), Copenhagen, the Department of Orthopedic Surgery, Aarhus University Hospital, and the Department of Clinical Medicine, Aarhus University, Aarhus (I.M., S.S.J.), the University Clinic for Orthopedic Pathways, Elective Surgery Center, Regional Hospital Silkeborg, Silkeborg (L.R.M.), and the Department of Orthopedic Surgery, Næstved Hospital, Næstved (M.J.B., H.Q., M.S.M.) - all in Denmark.

Mohammad S Munir (MS)

From the Departments of Physiotherapy (T.F., K.G.I.) and Orthopedic Surgery (C.V., A.E.G., P.K.-A., P.H.R., C.H.), Lillebaelt Hospital-University Hospital of Southern Denmark, Vejle Hospital, Vejle, the Departments of Clinical Research (T.F., R.C., S.M.N.) and Regional Health Research (C.V., K.G.I.), University of Southern Denmark, and the Research Unit of Rheumatology, Department of Clinical Research (R.C., S.M.N.), and the Department of Orthopedic Surgery and Traumatology (S.O.), Odense University Hospital, Odense, the Section for Biostatistics and Evidence-based Research, Parker Institute, Bispebjerg and Frederiksberg Hospital (T.F., R.C., S.M.N., K.G.I.), the Department of Orthopedic Surgery and Traumatology, Copenhagen University Hospital Bispebjerg (S.O.), and the Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen (S.O.), Copenhagen, the Department of Orthopedic Surgery, Aarhus University Hospital, and the Department of Clinical Medicine, Aarhus University, Aarhus (I.M., S.S.J.), the University Clinic for Orthopedic Pathways, Elective Surgery Center, Regional Hospital Silkeborg, Silkeborg (L.R.M.), and the Department of Orthopedic Surgery, Næstved Hospital, Næstved (M.J.B., H.Q., M.S.M.) - all in Denmark.

Stig S Jakobsen (SS)

From the Departments of Physiotherapy (T.F., K.G.I.) and Orthopedic Surgery (C.V., A.E.G., P.K.-A., P.H.R., C.H.), Lillebaelt Hospital-University Hospital of Southern Denmark, Vejle Hospital, Vejle, the Departments of Clinical Research (T.F., R.C., S.M.N.) and Regional Health Research (C.V., K.G.I.), University of Southern Denmark, and the Research Unit of Rheumatology, Department of Clinical Research (R.C., S.M.N.), and the Department of Orthopedic Surgery and Traumatology (S.O.), Odense University Hospital, Odense, the Section for Biostatistics and Evidence-based Research, Parker Institute, Bispebjerg and Frederiksberg Hospital (T.F., R.C., S.M.N., K.G.I.), the Department of Orthopedic Surgery and Traumatology, Copenhagen University Hospital Bispebjerg (S.O.), and the Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen (S.O.), Copenhagen, the Department of Orthopedic Surgery, Aarhus University Hospital, and the Department of Clinical Medicine, Aarhus University, Aarhus (I.M., S.S.J.), the University Clinic for Orthopedic Pathways, Elective Surgery Center, Regional Hospital Silkeborg, Silkeborg (L.R.M.), and the Department of Orthopedic Surgery, Næstved Hospital, Næstved (M.J.B., H.Q., M.S.M.) - all in Denmark.

Sabrina M Nielsen (SM)

From the Departments of Physiotherapy (T.F., K.G.I.) and Orthopedic Surgery (C.V., A.E.G., P.K.-A., P.H.R., C.H.), Lillebaelt Hospital-University Hospital of Southern Denmark, Vejle Hospital, Vejle, the Departments of Clinical Research (T.F., R.C., S.M.N.) and Regional Health Research (C.V., K.G.I.), University of Southern Denmark, and the Research Unit of Rheumatology, Department of Clinical Research (R.C., S.M.N.), and the Department of Orthopedic Surgery and Traumatology (S.O.), Odense University Hospital, Odense, the Section for Biostatistics and Evidence-based Research, Parker Institute, Bispebjerg and Frederiksberg Hospital (T.F., R.C., S.M.N., K.G.I.), the Department of Orthopedic Surgery and Traumatology, Copenhagen University Hospital Bispebjerg (S.O.), and the Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen (S.O.), Copenhagen, the Department of Orthopedic Surgery, Aarhus University Hospital, and the Department of Clinical Medicine, Aarhus University, Aarhus (I.M., S.S.J.), the University Clinic for Orthopedic Pathways, Elective Surgery Center, Regional Hospital Silkeborg, Silkeborg (L.R.M.), and the Department of Orthopedic Surgery, Næstved Hospital, Næstved (M.J.B., H.Q., M.S.M.) - all in Denmark.

Kim G Ingwersen (KG)

From the Departments of Physiotherapy (T.F., K.G.I.) and Orthopedic Surgery (C.V., A.E.G., P.K.-A., P.H.R., C.H.), Lillebaelt Hospital-University Hospital of Southern Denmark, Vejle Hospital, Vejle, the Departments of Clinical Research (T.F., R.C., S.M.N.) and Regional Health Research (C.V., K.G.I.), University of Southern Denmark, and the Research Unit of Rheumatology, Department of Clinical Research (R.C., S.M.N.), and the Department of Orthopedic Surgery and Traumatology (S.O.), Odense University Hospital, Odense, the Section for Biostatistics and Evidence-based Research, Parker Institute, Bispebjerg and Frederiksberg Hospital (T.F., R.C., S.M.N., K.G.I.), the Department of Orthopedic Surgery and Traumatology, Copenhagen University Hospital Bispebjerg (S.O.), and the Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen (S.O.), Copenhagen, the Department of Orthopedic Surgery, Aarhus University Hospital, and the Department of Clinical Medicine, Aarhus University, Aarhus (I.M., S.S.J.), the University Clinic for Orthopedic Pathways, Elective Surgery Center, Regional Hospital Silkeborg, Silkeborg (L.R.M.), and the Department of Orthopedic Surgery, Næstved Hospital, Næstved (M.J.B., H.Q., M.S.M.) - all in Denmark.

Søren Overgaard (S)

From the Departments of Physiotherapy (T.F., K.G.I.) and Orthopedic Surgery (C.V., A.E.G., P.K.-A., P.H.R., C.H.), Lillebaelt Hospital-University Hospital of Southern Denmark, Vejle Hospital, Vejle, the Departments of Clinical Research (T.F., R.C., S.M.N.) and Regional Health Research (C.V., K.G.I.), University of Southern Denmark, and the Research Unit of Rheumatology, Department of Clinical Research (R.C., S.M.N.), and the Department of Orthopedic Surgery and Traumatology (S.O.), Odense University Hospital, Odense, the Section for Biostatistics and Evidence-based Research, Parker Institute, Bispebjerg and Frederiksberg Hospital (T.F., R.C., S.M.N., K.G.I.), the Department of Orthopedic Surgery and Traumatology, Copenhagen University Hospital Bispebjerg (S.O.), and the Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen (S.O.), Copenhagen, the Department of Orthopedic Surgery, Aarhus University Hospital, and the Department of Clinical Medicine, Aarhus University, Aarhus (I.M., S.S.J.), the University Clinic for Orthopedic Pathways, Elective Surgery Center, Regional Hospital Silkeborg, Silkeborg (L.R.M.), and the Department of Orthopedic Surgery, Næstved Hospital, Næstved (M.J.B., H.Q., M.S.M.) - all in Denmark.

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Classifications MeSH

questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Sujet âgé › Total Hip Replacement or Resistance Training...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Total Hip Replacement or Resistance Training...
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Adulte d'âge moyen › Total Hip Replacement or Resistance Training...
questionsmedicales.fr › Procédures de chirurgie opératoire › Implantation de prothèse › Arthroplastie prothétique › Arthroplastie prothétique de hanche › Total Hip Replacement or Resistance Training...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études cliniques comme sujet › Essais cliniques comme sujet › Essais cliniques contrôlés comme sujet › Essais contrôlés randomisés comme sujet › Analyse en intention de traitement › Total Hip Replacement or Resistance Training...
questionsmedicales.fr › Maladies ostéomusculaires › Arthrose › Coxarthrose › Total Hip Replacement or Resistance Training...
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Examen physique › Examen neurologique › Mesure de la douleur › Total Hip Replacement or Resistance Training...
questionsmedicales.fr › Activités humaines › Exercice physique › Mise en condition physique de l'homme › Entraînement en résistance › Total Hip Replacement or Resistance Training...
questionsmedicales.fr › Phénomènes physiologiques de l'appareil locomoteur et du système nerveux › Phénomènes physiologiques du système nerveux › Sensation › Douleur › Arthralgie › Total Hip Replacement or Resistance Training...