Progressive plasticity during colorectal cancer metastasis.


Journal

Nature
ISSN: 1476-4687
Titre abrégé: Nature
Pays: England
ID NLM: 0410462

Informations de publication

Date de publication:
30 Oct 2024
Historique:
received: 10 07 2023
accepted: 02 10 2024
medline: 31 10 2024
pubmed: 31 10 2024
entrez: 31 10 2024
Statut: aheadofprint

Résumé

As cancers progress, they become increasingly aggressive-metastatic tumours are less responsive to first-line therapies than primary tumours, they acquire resistance to successive therapies and eventually cause death

Identifiants

pubmed: 39478232
doi: 10.1038/s41586-024-08150-0
pii: 10.1038/s41586-024-08150-0
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2024. The Author(s).

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Auteurs

A R Moorman (AR)

Computational and Systems Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

E K Benitez (EK)

Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Weill Cornell/Rockefeller/Sloan Kettering Tri-Institutional MD-PhD Program, New York, NY, USA.

F Cambuli (F)

Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
New York Genome Center, New York, NY, USA.

Q Jiang (Q)

Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

A Mahmoud (A)

Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Pharmacology Program, Weill Cornell Graduate School, New York, NY, USA.

M Lumish (M)

Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Case Western Reserve University, Cleveland, OH, USA.

S Hartner (S)

Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

S Balkaran (S)

Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

J Bermeo (J)

Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

S Asawa (S)

Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

C Firat (C)

Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

A Saxena (A)

Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

F Wu (F)

Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

A Luthra (A)

Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

C Burdziak (C)

Computational and Systems Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Y Xie (Y)

Computational and Systems Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Tri-Institutional PhD Program in Computational Biology and Medicine, New York, NY, USA.

V Sgambati (V)

Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

K Luckett (K)

Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Weill Cornell/Rockefeller/Sloan Kettering Tri-Institutional MD-PhD Program, New York, NY, USA.

Y Li (Y)

Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Bristol Myers Squibb, Princeton, NJ, USA.

Z Yi (Z)

Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

I Masilionis (I)

Computational and Systems Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

K Soares (K)

Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

E Pappou (E)

Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Howard Hughes Medical Institute, Chevy Chase, MD, USA.

R Yaeger (R)

Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

P Kingham (P)

Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

W Jarnagin (W)

Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

P Paty (P)

Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

M R Weiser (MR)

Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

L Mazutis (L)

Computational and Systems Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

M D'Angelica (M)

Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

J Shia (J)

Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

J Garcia-Aguilar (J)

Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

T Nawy (T)

Computational and Systems Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

T J Hollmann (TJ)

Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Bristol Myers Squibb, Princeton, NJ, USA.

R Chaligné (R)

Computational and Systems Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

F Sanchez-Vega (F)

Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

R Sharma (R)

Computational and Systems Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

D Pe'er (D)

Computational and Systems Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA. peerd@mskcc.org.
Howard Hughes Medical Institute, Chevy Chase, MD, USA. peerd@mskcc.org.

K Ganesh (K)

Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA. ganeshk@mskcc.org.
Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA. ganeshk@mskcc.org.

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