Prenatal exposure to air pollution during the early and middle stages of pregnancy is associated with adverse neurodevelopmental outcomes at ages 1 to 3 years.
Humans
Female
Pregnancy
Prenatal Exposure Delayed Effects
/ epidemiology
Child, Preschool
Infant
Air Pollutants
/ adverse effects
New York City
/ epidemiology
Particulate Matter
/ analysis
Nitrogen Dioxide
/ analysis
Maternal Exposure
/ adverse effects
Male
Air Pollution
/ adverse effects
Adult
Prospective Studies
Black or African American
/ statistics & numerical data
Hispanic or Latino
/ statistics & numerical data
Child Development
/ drug effects
Neurodevelopmental Disorders
/ epidemiology
Young Adult
Air pollution
Children
Critical windows
Neurodevelopment
Prenatal
Journal
Environmental health : a global access science source
ISSN: 1476-069X
Titre abrégé: Environ Health
Pays: England
ID NLM: 101147645
Informations de publication
Date de publication:
30 Oct 2024
30 Oct 2024
Historique:
received:
24
05
2024
accepted:
15
10
2024
medline:
31
10
2024
pubmed:
31
10
2024
entrez:
31
10
2024
Statut:
epublish
Résumé
A large body of data shows that fetal brain development is vulnerable to disruption by air pollution experienced by the mother during pregnancy, adversely affecting cognitive and psychomotor capabilities during childhood (De Asis-Cruz et al., Biol Psychiatry 7:480-90, 2022; Morgan ZEM et al., Environ Health 22:11, 2023). This study has sought to identify gestational windows of susceptibility to prenatal exposure to air pollution. 470 African American and Latina mother/child pairs participated in a prospective cohort study based in the low-income communities of Northern Manhattan and the South Bronx, New York City. Gestational exposure to respirable particulate matter (PM By linear regression, average exposures to NO Our finding that prenatal exposure to air pollution in the first and second trimesters was associated with lower scores for cognitive development at ages 1 and 3 is of concern because of the potential consequences of these outcomes for long-term functioning. They underscore the need for stronger policies to protect pregnant individuals and offspring, particularly during vulnerable, early life-stage of development.
Sections du résumé
BACKGROUND
BACKGROUND
A large body of data shows that fetal brain development is vulnerable to disruption by air pollution experienced by the mother during pregnancy, adversely affecting cognitive and psychomotor capabilities during childhood (De Asis-Cruz et al., Biol Psychiatry 7:480-90, 2022; Morgan ZEM et al., Environ Health 22:11, 2023). This study has sought to identify gestational windows of susceptibility to prenatal exposure to air pollution.
METHODS
METHODS
470 African American and Latina mother/child pairs participated in a prospective cohort study based in the low-income communities of Northern Manhattan and the South Bronx, New York City. Gestational exposure to respirable particulate matter (PM
RESULTS
RESULTS
By linear regression, average exposures to NO
CONCLUSIONS
CONCLUSIONS
Our finding that prenatal exposure to air pollution in the first and second trimesters was associated with lower scores for cognitive development at ages 1 and 3 is of concern because of the potential consequences of these outcomes for long-term functioning. They underscore the need for stronger policies to protect pregnant individuals and offspring, particularly during vulnerable, early life-stage of development.
Identifiants
pubmed: 39478594
doi: 10.1186/s12940-024-01132-9
pii: 10.1186/s12940-024-01132-9
doi:
Substances chimiques
Air Pollutants
0
Particulate Matter
0
Nitrogen Dioxide
S7G510RUBH
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
95Informations de copyright
© 2024. The Author(s).
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