Concomitant sarcoidosis, psoriasis, and eczema - immune patterns on the skin.
Autoimmunity
Eczema
Psoriasis
Sarcoidosis
TNF alpha
Journal
Orphanet journal of rare diseases
ISSN: 1750-1172
Titre abrégé: Orphanet J Rare Dis
Pays: England
ID NLM: 101266602
Informations de publication
Date de publication:
30 Oct 2024
30 Oct 2024
Historique:
received:
17
05
2024
accepted:
20
10
2024
medline:
31
10
2024
pubmed:
31
10
2024
entrez:
31
10
2024
Statut:
epublish
Résumé
Sarcoidosis is a rare and elusive chronic inflammatory disease. It can manifest itself in any organ, but preferentially affects the lungs and the skin. Our case of an elderly woman with cutaneous and pulmonary sarcoidosis presented with exacerbated itchy, scaly skin changes to our department. The clinical and histopathological findings were consistent with sarcoidosis and eczematized psoriasis. The case represents a unique presentation of sarcoidosis with cutaneous involvement and poses diagnostic and therapeutic challenges due to overlapping clinical features and histology covering the three diagnoses. We discuss the immunological complexities underlying this overlap and resulting possible treatment options, highlighting the role of dermatology in systemic autoimmune diseases involving the skin and the need for pathophysiology-based tailored management approaches in these diseases.
Identifiants
pubmed: 39478628
doi: 10.1186/s13023-024-03427-z
pii: 10.1186/s13023-024-03427-z
doi:
Types de publication
Case Reports
Letter
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
404Informations de copyright
© 2024. The Author(s).
Références
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