Application of Carbon Nanomaterials to Enhancing Tumor Immunotherapy: Current Advances and Prospects.


Journal

International journal of nanomedicine
ISSN: 1178-2013
Titre abrégé: Int J Nanomedicine
Pays: New Zealand
ID NLM: 101263847

Informations de publication

Date de publication:
2024
Historique:
received: 01 06 2024
accepted: 15 10 2024
medline: 31 10 2024
pubmed: 31 10 2024
entrez: 31 10 2024
Statut: epublish

Résumé

Recent advances in tumor immunotherapy have highlighted the pivotal role of carbon nanomaterials, such as carbon dots, graphene quantum dots, and carbon nanotubes. This review examines the unique benefits of these materials in cancer treatment, focusing on their mechanisms of action within immunotherapy. These include applications in immunoregulation, recognition, and enhancement. We explore how these nanomaterials when combined with specific biomolecules, can form immunosensors. These sensors are engineered for highly sensitive and specific detection of tumor markers, offering crucial support for early diagnosis and timely therapeutic interventions. This review also addresses significant challenges facing carbon nanomaterials in clinical settings, such as issues related to long-term biocompatibility and the hurdles of clinical translation. These challenges require extensive ongoing research and discussion. This review is of both theoretical and practical importance, aiming to promote using carbon nanomaterials in tumor immunotherapy, potentially transforming clinical outcomes and enhancing patient care.

Identifiants

pubmed: 39479174
doi: 10.2147/IJN.S480799
pii: 480799
pmc: PMC11524014
doi:

Substances chimiques

Nanotubes, Carbon 0
Graphite 7782-42-5
Carbon 7440-44-0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

10899-10915

Informations de copyright

© 2024 Li et al.

Déclaration de conflit d'intérêts

The authors report no conflicts of interest in this work.

Auteurs

Yun Li (Y)

State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, People's Republic of China.
University of Chinese Academy of Sciences, Beijing, People's Republic of China.

Zhijie Xu (Z)

Department of Pathology, Xiangya Hospital, Central South University, Changsha, Hunan, People's Republic of China.

Zijuan Qi (Z)

Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, Shandong, People's Republic of China.

Xiaofeng Huang (X)

State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, People's Republic of China.
University of Chinese Academy of Sciences, Beijing, People's Republic of China.

Mingyu Li (M)

Mudanjiang Medical University, Mu Danjiang, Hei Longjiang, People's Republic of China.

Sijin Liu (S)

State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, People's Republic of China.
University of Chinese Academy of Sciences, Beijing, People's Republic of China.

Yuanliang Yan (Y)

Department of Pharmacy, National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan, People's Republic of China.

Ming Gao (M)

State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, People's Republic of China.
University of Chinese Academy of Sciences, Beijing, People's Republic of China.

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Classifications MeSH