Application of Carbon Nanomaterials to Enhancing Tumor Immunotherapy: Current Advances and Prospects.
carbon nanoparticles
drug delivery
immune cell
immunosensors
tumor immunotherapy
Journal
International journal of nanomedicine
ISSN: 1178-2013
Titre abrégé: Int J Nanomedicine
Pays: New Zealand
ID NLM: 101263847
Informations de publication
Date de publication:
2024
2024
Historique:
received:
01
06
2024
accepted:
15
10
2024
medline:
31
10
2024
pubmed:
31
10
2024
entrez:
31
10
2024
Statut:
epublish
Résumé
Recent advances in tumor immunotherapy have highlighted the pivotal role of carbon nanomaterials, such as carbon dots, graphene quantum dots, and carbon nanotubes. This review examines the unique benefits of these materials in cancer treatment, focusing on their mechanisms of action within immunotherapy. These include applications in immunoregulation, recognition, and enhancement. We explore how these nanomaterials when combined with specific biomolecules, can form immunosensors. These sensors are engineered for highly sensitive and specific detection of tumor markers, offering crucial support for early diagnosis and timely therapeutic interventions. This review also addresses significant challenges facing carbon nanomaterials in clinical settings, such as issues related to long-term biocompatibility and the hurdles of clinical translation. These challenges require extensive ongoing research and discussion. This review is of both theoretical and practical importance, aiming to promote using carbon nanomaterials in tumor immunotherapy, potentially transforming clinical outcomes and enhancing patient care.
Identifiants
pubmed: 39479174
doi: 10.2147/IJN.S480799
pii: 480799
pmc: PMC11524014
doi:
Substances chimiques
Nanotubes, Carbon
0
Graphite
7782-42-5
Carbon
7440-44-0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
10899-10915Informations de copyright
© 2024 Li et al.
Déclaration de conflit d'intérêts
The authors report no conflicts of interest in this work.