Some brain disorders are "chaperonopathies".

Humans Molecular Chaperones / metabolism Brain / metabolism Protein Folding Mutation Animals Brain Diseases / genetics

Journal

Science (New York, N.Y.)

ISSN: 1095-9203

Titre abrégé: Science

Pays: United States

ID NLM: 0404511

Informations de publication

Date de publication:
Nov 2024

Historique:

medline: 1 11 2024

pubmed: 1 11 2024

entrez: 31 10 2024

Statut: ppublish

Résumé

Mutations that impair a protein-folding chaperone can lead to brain malformations.

Identifiants

DOI: 10.1126/science.adt0039 PMID: 39480954

pubmed: 39480954

doi: 10.1126/science.adt0039

doi:

Substances chimiques

Molecular Chaperones 0

Types de publication

News Journal Article Comment

Langues

eng

Sous-ensembles de citation

Pagination

496-497

Commentaires et corrections

Type : CommentOn

Auteurs

Manu Sharma (M)

Appel Alzheimer's Disease Research Institute and Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY, USA.

Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Some brain disorders are "chaperonopathies".

questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Chaperons moléculaires › Some brain disorders are "chaperonopathies".

questionsmedicales.fr › Système nerveux › Système nerveux central › Encéphale › Some brain disorders are "chaperonopathies".

questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Pliage des protéines › Some brain disorders are "chaperonopathies".

questionsmedicales.fr › Phénomènes génétiques › Variation génétique › Mutation › Some brain disorders are "chaperonopathies".

questionsmedicales.fr › Eucaryotes › Animaux › Some brain disorders are "chaperonopathies".

questionsmedicales.fr › Maladies du système nerveux › Maladies du système nerveux central › Encéphalopathies › Some brain disorders are "chaperonopathies".