Humans
Carcinoma, Renal Cell
/ diagnostic imaging
Vena Cava, Inferior
/ diagnostic imaging
Male
Female
Positron Emission Tomography Computed Tomography
Fluorodeoxyglucose F18
Kidney Neoplasms
/ diagnostic imaging
Middle Aged
Retrospective Studies
Neoplasm Invasiveness
Aged
Case-Control Studies
Radiopharmaceuticals
Adult
Venous Thrombosis
/ diagnostic imaging
Inferior vena cava wall invasion
Positron emission tomography-computed tomography
Renal cell carcinoma
Tomography (X-ray computed)
Venous tumor thrombus
Journal
BMC medical imaging
ISSN: 1471-2342
Titre abrégé: BMC Med Imaging
Pays: England
ID NLM: 100968553
Informations de publication
Date de publication:
31 Oct 2024
31 Oct 2024
Historique:
received:
08
01
2023
accepted:
15
10
2024
medline:
1
11
2024
pubmed:
1
11
2024
entrez:
1
11
2024
Statut:
epublish
Résumé
Preoperative evaluation of inferior vena cava (IVC) wall invasion is very important to improve outcomes of patients with renal cell carcinoma (RCC), and may allow surgical urologists to treat the IVC more effectively. The objective of this study was to evaluate preoperative This retrospective case-control study evaluated 68 patients with RCC with level I-IV tumor thrombus. According to the histopathologic examination result, the patients were divided into IVC wall invasion group and non-invasion group. The Sixty-eight patients were evaluated, and 55.9% (38/68) had IVC wall invasion. Compared with non-invasion group, invasion group had higher SUVmax of RCC, higher SURmax (tumor to tumor thrombus ratio, Tu/Th), higher IVCTT coronal diameter, and longer IVCTT craniocaudal extent (all p < 0.05). Multivariate analysis showed that SURmax (Tu/Th) (OR 8.760 [95%CI, 1.019-75.310]; p = 0.048) and the maximum coronal diameter of IVCTT (OR 1.143 [95%CI, 1.029-1.269]; p = 0.028) were predictors of IVC wall invasion. A model combining SURmax (Tu/Th) and the maximum coronal diameter of IVCTT achieved an AUC of 0.855 (95%CI, 0.757-0.954). The specificity and sensitivity for assessing IVC wall invasion was 92.1% and 76.7%, respectively. Increases in SURmax (Tu/Th) and the maximum coronal diameter of IVCTT are associated with a higher probability of IVC wall invasion. Preoperative
Identifiants
pubmed: 39482592
doi: 10.1186/s12880-024-01466-3
pii: 10.1186/s12880-024-01466-3
doi:
Substances chimiques
Fluorodeoxyglucose F18
0Z5B2CJX4D
Radiopharmaceuticals
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
295Informations de copyright
© 2024. The Author(s).
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