Initial pH determines the morphological characteristics and secondary metabolite production in Aspergillus terreus and Streptomyces rimosus cocultures.
Aspergillus terreus
Streptomyces rimosus
Coculture
Secondary metabolites
Journal
Archives of microbiology
ISSN: 1432-072X
Titre abrégé: Arch Microbiol
Pays: Germany
ID NLM: 0410427
Informations de publication
Date de publication:
01 Nov 2024
01 Nov 2024
Historique:
received:
23
07
2024
accepted:
26
10
2024
revised:
10
10
2024
medline:
1
11
2024
pubmed:
1
11
2024
entrez:
1
11
2024
Statut:
epublish
Résumé
The influence of the initial pH on the morphology and secondary metabolite production in cocultures and axenic cultures of Aspergillus terreus and Streptomyces rimosus was investigated. The detected secondary metabolites (6 of bacterial and 4 of fungal origin) were not found in the cultures initiated at pH values less than or equal to 4.0. The highest mean levels of oxytetracycline were recorded in S. rimosus axenic culture at pH 5.0. Initiating the axenic culture at pH 5.9 led to visibly lower product levels, yet the presence of A. terreus reduced the negative effect of non-optimal pH and led to higher oxytetracycline titer than in the corresponding S. rimosus axenic culture. The cocultivation initiated at pH 5.0 or 5.9 triggered the formation of oxidized rimocidin. The products of A. terreus were absent in the cocultures. At pH 4.0, the striking morphological differences between the coculture and the axenic cultures were recorded.
Identifiants
pubmed: 39485516
doi: 10.1007/s00203-024-04186-y
pii: 10.1007/s00203-024-04186-y
doi:
Substances chimiques
Culture Media
0
Oxytetracycline
X20I9EN955
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
452Subventions
Organisme : Narodowe Centrum Nauki
ID : 2017/27/B/NZ9/00534
Organisme : Narodowe Centrum Nauki
ID : 2017/27/B/NZ9/00534
Informations de copyright
© 2024. The Author(s).
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