John A Shupe

Affiliations

Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America.

Publications (5)

Nanobodies against C. difficile TcdA and TcdB reveal unexpected neutralizing epitopes and provide a toolkit for toxin quantitation in vivo.

PLoS pathogens

Avec: Shannon L Kordus , Heather K Kroh , Rubén Cano Rodríguez , Rebecca A Shrem , F Christopher Peritore-Galve , Brian E Wadzinski , D Borden Lacy , Benjamin W Spiller

Clostridioides difficile infection induces a rapid influx of bile acids into the gut during colonization of the host.

Cell reports

Avec: Aaron G Wexler , Emma R Guiberson , William N Beavers , M Kay Washington , D Borden Lacy , Richard M Caprioli , Jeffrey M Spraggins , Eric P Skaar

Glucosyltransferase-dependent and independent effects of Clostridioides difficile toxins during infection.

PLoS pathogens

Avec: F Christopher Peritore-Galve , Rory J Cave , Kevin O Childress , M Kay Washington , Sarah A Kuehne , D Borden Lacy

Proceedings of the National Academy of Sciences of the United States of America

Avec: Steven J Mileto , Thierry Jardé , Kevin O Childress , Jaime L Jensen , Ashleigh P Rogers , Genevieve Kerr , Melanie L Hutton , Michael J Sheedlo , Sarah C Bloch , Katja Horvay , Tracey Flores , Rebekah Engel , Simon Wilkins , Paul J McMurrick , D Borden Lacy , Helen E Abud , Dena Lyras

Purified CDT toxins and a clean deletion within the CDT locus provide novel insights into the contribution of binary toxin in cellular inflammation and Clostridioides difficile infection.

PLoS pathogens

Avec: Kateryna Nabukhotna , Shannon L Kordus , Rubén Cano Rodríguez , Anna Smith , Julia K Bohannon , M Kay Washington , D Borden Lacy

Réseau de co-auteurs

D Borden Lacy 5 collaborations

M Kay Washington 3 collaborations

Shannon L Kordus 2 collaborations

Rubén Cano Rodríguez 2 collaborations

F Christopher Peritore-Galve 2 collaborations

Kevin O Childress 2 collaborations

Heather K Kroh 1 collaboration

Rebecca A Shrem 1 collaboration

Brian E Wadzinski 1 collaboration

Benjamin W Spiller 1 collaboration

Aaron G Wexler 1 collaboration

Emma R Guiberson 1 collaboration

William N Beavers 1 collaboration

Richard M Caprioli 1 collaboration

Jeffrey M Spraggins 1 collaboration

Eric P Skaar 1 collaboration

Rory J Cave 1 collaboration

Sarah A Kuehne 1 collaboration

Steven J Mileto 1 collaboration

Thierry Jardé 1 collaboration

Jaime L Jensen 1 collaboration

Ashleigh P Rogers 1 collaboration

Genevieve Kerr 1 collaboration

Melanie L Hutton 1 collaboration

Michael J Sheedlo 1 collaboration

Sarah C Bloch 1 collaboration

Katja Horvay 1 collaboration

Tracey Flores 1 collaboration

Rebekah Engel 1 collaboration

Simon Wilkins 1 collaboration

Paul J McMurrick 1 collaboration

Helen E Abud 1 collaboration

Dena Lyras 1 collaboration

Kateryna Nabukhotna 1 collaboration

Anna Smith 1 collaboration

Julia K Bohannon 1 collaboration