Alexis Digman

Affiliations

Department of Pharmaceutical Science, College of Pharmacy and Pharmaceutical Sciences, Florida A&M University, Tallahassee, FL, USA 32307.

Publications (11)

Dopaminergic REST/NRSF is protective against manganese-induced neurotoxicity in mice.

The Journal of biological chemistry

Avec: Edward Pajarillo , Sanghoon Kim , Alexis Digman , Itunu Ajayi , Ivan Nyarko-Danquah , Deok-Soo Son , Michael Aschner , Eunsook Lee

Astrocytic transcription factor REST upregulates glutamate transporter EAAT2, protecting dopaminergic neurons from manganese-induced excitotoxicity.

The Journal of biological chemistry

Avec: Edward Pajarillo , Alexis Digman , Ivan Nyarko-Danquah , Deok-Soo Son , Karam F A Soliman , Michael Aschner , Eunsook Lee

The role of microglial LRRK2 kinase in manganese-induced inflammatory neurotoxicity via NLRP3 inflammasome and RAB10-mediated autophagy dysfunction.

The Journal of biological chemistry

Avec: Edward Pajarillo , Sanghoon Kim , Alexis Digman , Matthew Dutton , Deok-Soo Son , Michael Aschner , Eunsook Lee

Manganese-induced reactive oxygen species activate IκB kinase to upregulate YY1 and impair glutamate transporter EAAT2 function in human astrocytes in vitro.

Neurotoxicology

Avec: Asha Rizor , Edward Pajarillo , Ivan Nyarko-Danquah , Alexis Digman , Leyah Mooneyham , Deok-Soo Son , Michael Aschner , Eunsook Lee

Astrocytic Yin Yang 1 is critical for murine brain development and protection against apoptosis, oxidative stress, and inflammation.

Glia

Avec: Edward Pajarillo , Ivan Nyarko-Danquah , Alexis Digman , Cynthia Vied , Deok-Soo Son , Jayden Lee , Michael Aschner , Eunsook Lee

Mechanisms of manganese-induced neurotoxicity and the pursuit of neurotherapeutic strategies.

Frontiers in pharmacology

Avec: Edward Pajarillo , Ivan Nyarko-Danquah , Alexis Digman , Harpreet Kaur Multani , Sanghoon Kim , Patric Gaspard , Michael Aschner , Eunsook Lee

Manganese Accumulation in the Brain via Various Transporters and Its Neurotoxicity Mechanisms.

Molecules (Basel, Switzerland)

Avec: Ivan Nyarko-Danquah , Edward Pajarillo , Alexis Digman , Karam F A Soliman , Michael Aschner , Eunsook Lee

Deletion of RE1-silencing transcription factor in striatal astrocytes exacerbates manganese-induced neurotoxicity in mice.

Glia

Avec: Edward Pajarillo , Mark Demayo , Alexis Digman , Ivan Nyarko-Danquah , Deok-Soo Son , Michael Aschner , Eunsook Lee

The role of microglial LRRK2 in manganese-induced inflammatory neurotoxicity via NLRP3 inflammasome and RAB10-mediated autophagy dysfunction.

bioRxiv : the preprint server for biology

Avec: Edward Pajarillo , Sang Hoon Kim , Alexis Digman , Matthew Dutton , Deok-Soo Son , Michael Aschner , Eunsook Lee

Student knowledge, confidence, and perceptions prior to and following an inhaler and tobacco cessation simulation.

Currents in pharmacy teaching & learning

Avec: Anastasia Digman , Ashleigh Barrickman , Angela Goodhart , Tara Whetsel

Microglial Sp1 induced LRRK2 upregulation in response to manganese exposure, and 17β-estradiol afforded protection against this manganese toxicity.

Neurotoxicology

Avec: Ivan Nyarko-Danquah , Edward Pajarillo , Sanghoon Kim , Alexis Digman , Harpreet Kaur Multani , Itunu Ajayi , Deok-Soo Son , Michael Aschner , Eunsook Lee

Réseau de co-auteurs

Edward Pajarillo 10 collaborations

Michael Aschner 10 collaborations

Eunsook Lee 10 collaborations

Ivan Nyarko-Danquah 8 collaborations

Deok-Soo Son 8 collaborations

Sanghoon Kim 4 collaborations

Itunu Ajayi 2 collaborations

Karam F A Soliman 2 collaborations

Matthew Dutton 2 collaborations

Harpreet Kaur Multani 2 collaborations

Asha Rizor 1 collaboration

Leyah Mooneyham 1 collaboration

Cynthia Vied 1 collaboration

Jayden Lee 1 collaboration

Patric Gaspard 1 collaboration

Mark Demayo 1 collaboration

Sang Hoon Kim 1 collaboration

Anastasia Digman 1 collaboration

Ashleigh Barrickman 1 collaboration

Angela Goodhart 1 collaboration

Tara Whetsel 1 collaboration