Andrew Leask

Affiliations

Division of Oral Biology, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Canada.

Publications (20)

Periostin and CCN2 Scaffolds Promote the Wound Healing Response in the Skin of Diabetic Mice.

Tissue engineering. Part A

Avec: Christopher G Elliott , Jiarong Wang , John T Walker , Sarah Michelsons , Joy Dunmore-Buyze , Maria Drangova , Andrew Leask , Douglas W Hamilton

Et tu, CCN1….

Journal of cell communication and signaling

Avec: Andrew Leask

Conjunction junction, what's the function? CCN proteins as targets in fibrosis and cancers.

American journal of physiology. Cell physiology

Avec: Andrew Leask

Post-traumatic osteoarthritis development is not modified by postnatal chondrocyte deletion of

Disease models & mechanisms

Avec: Craig M Keenan , Lorenzo Ramos-Mucci , Ioannis Kanakis , Peter I Milner , Andrew Leask , David Abraham , George Bou-Gharios , Blandine Poulet

A CTGF-YAP Regulatory Pathway Is Essential for Angiogenesis and Barriergenesis in the Retina.

iScience

Avec: Sohyun Moon , Sangmi Lee , Joy Ann Caesar , Sarah Pruchenko , Andrew Leask , James A Knowles , Jose Sinon , Brahim Chaqour

Verteporfin inhibits the persistent fibrotic phenotype of lesional scleroderma dermal fibroblasts.

Journal of cell communication and signaling

Avec: Xu Shi-Wen , Michael Racanelli , Aaisham Ali , Amara Simon , Katherine Quesnel , Richard J Stratton , Andrew Leask

CCN1 expression by fibroblasts is required for bleomycin-induced skin fibrosis.

Matrix biology plus

Avec: Katherine Quesnel , Xu Shi-Wen , James Hutchenreuther , Yizhi Xiao , Shangxi Liu , Alexander Peidl , Deboki Naskar , Walter L Siqueira , David B O'Gorman , Boris Hinz , Richard J Stratton , Andrew Leask

Blisters on your fingers.

Journal of cell communication and signaling

Avec: Andrew Leask

Collagen type XIX regulates cardiac extracellular matrix structure and ventricular function.

Matrix biology : journal of the International Society for Matrix Biology

Avec: Ghazal Sadri , Annalara G Fischer , Kenneth R Brittian , Erin Elliott , Matthew A Nystoriak , Shizuka Uchida , Marcin Wysoczynski , Andrew Leask , Steven P Jones , Joseph B Moore

Tumor-associated fibrosis impairs the response to immunotherapy.

Matrix biology : journal of the International Society for Matrix Biology

Avec: Angha Naik , Andrew Leask

The yes-associated protein-1 (YAP1) inhibitor celastrol suppresses the ability of transforming growth factor β to activate human gingival fibroblasts.

Archives of oral biology

Avec: Angha Naik , Pratyusha Chitturi , John Nguyen , Andrew Leask

Digital ulcers associated with scleroderma: A major unmet medical need.

Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society

Avec: Angha Naik , Richard J Stratton , Andrew Leask

Epithelial Vasopressin Type-2 Receptors Regulate Myofibroblasts by a YAP-CCN2-Dependent Mechanism in Polycystic Kidney Disease.

Journal of the American Society of Nephrology : JASN

Avec: Nidhi Dwivedi , Shixin Tao , Abeda Jamadar , Sonali Sinha , Christianna Howard , Darren P Wallace , Timothy A Fields , Andrew Leask , James P Calvet , Reena Rao

COVID-19: is fibrosis the killer?

Journal of cell communication and signaling

Avec: Andrew Leask

Slow train coming: an anti-CCN2 strategy reverses a model of chronic overuse muscle fibrosis.

Journal of cell communication and signaling

Avec: Andrew Leask

The Matrix Revolution: Matricellular Proteins and Restructuring of the Cancer Microenvironment.

Cancer research

Avec: Casimiro Gerarduzzi , Ursula Hartmann , Andrew Leask , Elliot Drobetsky

Using the Bleomycin-Induced Model of Fibrosis to Study the Contribution of CCN Proteins to Scleroderma Fibrosis.

Methods in molecular biology (Clifton, N.J.)

Avec: Alexander Peidl , John Nguyen , Pratyusha Chitturi , Bruce L Riser , Andrew Leask

Annals of the rheumatic diseases

Avec: Pratyusha Chitturi , Shiwen Xu , Bahja Ahmed Abdi , John Nguyen , David E Carter , Sartak Sinha , Rohit Arora , Jeff Biernaskie , Richard J Stratton , Andrew Leask

CCN2 deficiency in smooth muscle cells triggers cell reprogramming and aggravates aneurysm development.

JCI insight

Avec: Yu Wang , Xuesong Liu , Qian Xu , Wei Xu , Xianming Zhou , Andrew Leask , Zhiyong Lin

A modest proposal: targeting αv integrin-mediated activation of latent TGFbeta as a novel therapeutic approach to treat scleroderma fibrosis.

Expert opinion on investigational drugs

Avec: Andrew Leask , Asmaa Fadl , Angha Naik

Réseau de co-auteurs

Richard J Stratton 4 collaborations

Angha Naik 4 collaborations

Pratyusha Chitturi 3 collaborations

John Nguyen 3 collaborations

Xu Shi-Wen 2 collaborations

Katherine Quesnel 2 collaborations

Alexander Peidl 2 collaborations

Christopher G Elliott 1 collaboration

Jiarong Wang 1 collaboration

John T Walker 1 collaboration

Sarah Michelsons 1 collaboration

Joy Dunmore-Buyze 1 collaboration

Maria Drangova 1 collaboration

Douglas W Hamilton 1 collaboration

Craig M Keenan 1 collaboration

Lorenzo Ramos-Mucci 1 collaboration

Ioannis Kanakis 1 collaboration

Peter I Milner 1 collaboration

David Abraham 1 collaboration

George Bou-Gharios 1 collaboration

Blandine Poulet 1 collaboration

Sohyun Moon 1 collaboration

Sangmi Lee 1 collaboration

Joy Ann Caesar 1 collaboration

Sarah Pruchenko 1 collaboration

James A Knowles 1 collaboration

Jose Sinon 1 collaboration

Brahim Chaqour 1 collaboration

Michael Racanelli 1 collaboration

Aaisham Ali 1 collaboration

Amara Simon 1 collaboration

James Hutchenreuther 1 collaboration

Yizhi Xiao 1 collaboration

Shangxi Liu 1 collaboration

Deboki Naskar 1 collaboration

Walter L Siqueira 1 collaboration

David B O'Gorman 1 collaboration

Boris Hinz 1 collaboration

Ghazal Sadri 1 collaboration

Annalara G Fischer 1 collaboration

Kenneth R Brittian 1 collaboration

Erin Elliott 1 collaboration

Matthew A Nystoriak 1 collaboration

Shizuka Uchida 1 collaboration

Marcin Wysoczynski 1 collaboration

Steven P Jones 1 collaboration

Joseph B Moore 1 collaboration

Nidhi Dwivedi 1 collaboration

Shixin Tao 1 collaboration

Abeda Jamadar 1 collaboration

Sonali Sinha 1 collaboration

Christianna Howard 1 collaboration

Darren P Wallace 1 collaboration

Timothy A Fields 1 collaboration

James P Calvet 1 collaboration

Reena Rao 1 collaboration

Casimiro Gerarduzzi 1 collaboration

Ursula Hartmann 1 collaboration

Elliot Drobetsky 1 collaboration

Bruce L Riser 1 collaboration

Shiwen Xu 1 collaboration

Bahja Ahmed Abdi 1 collaboration

David E Carter 1 collaboration

Sartak Sinha 1 collaboration

Rohit Arora 1 collaboration

Jeff Biernaskie 1 collaboration

Yu Wang 1 collaboration

Xuesong Liu 1 collaboration

Qian Xu 1 collaboration

Wei Xu 1 collaboration

Xianming Zhou 1 collaboration

Zhiyong Lin 1 collaboration

Asmaa Fadl 1 collaboration