Andrew T Ferenbach

Affiliations

School of Life Sciences, University of Dundee, Dundee, DD1 5EH, UK.

Publications (13)

Mechanisms of redundancy and specificity of the Aspergillus fumigatus Crh transglycosylases.

Nature communications

Avec: Wenxia Fang , Ana Belén Sanz , Sergio Galan Bartual , Bin Wang , Andrew T Ferenbach , Vladimír Farkaš , Ramon Hurtado-Guerrero , Javier Arroyo , Daan M F van Aalten

Neuroectoderm phenotypes in a human stem cell model of O-GlcNAc transferase associated with intellectual disability.

Molecular genetics and metabolism

Avec: Marta Murray , Lindsay Davidson , Andrew T Ferenbach , Dirk Lefeber , Daan M F van Aalten

Genetic and structural validation of phosphomannomutase as a cell wall target in Aspergillus fumigatus.

Molecular microbiology

Avec: Yuanwei Zhang , Wenxia Fang , Olawale G Raimi , Deborah E A Lockhart , Andrew T Ferenbach , Ling Lu , Daan M F van Aalten

Intellectual disability-associated disruption of O-GlcNAc cycling impairs habituation learning in Drosophila.

PLoS genetics

Avec: Michaela Fenckova , Villo Muha , Daniel Mariappa , Marica Catinozzi , Ignacy Czajewski , Laura E R Blok , Andrew T Ferenbach , Erik Storkebaum , Annette Schenck , Daan M F van Aalten

Neurodevelopmental defects in a mouse model of O-GlcNAc transferase intellectual disability.

Disease models & mechanisms

Avec: Florence Authier , Nina Ondruskova , Andrew T Ferenbach , Alison McNeilly , Daan M F van Aalten

O-GlcNAcylation enhances CPS1 catalytic efficiency for ammonia and promotes ureagenesis.

Nature communications

Avec: Leandro R Soria , Georgios Makris , Alfonso M D'Alessio , Angela De Angelis , Iolanda Boffa , Veronica M Pravata , Véronique Rüfenacht , Sergio Attanasio , Edoardo Nusco , Paola Arena , Andrew T Ferenbach , Debora Paris , Paola Cuomo , Andrea Motta , Matthew Nitzahn , Gerald S Lipshutz , Ainhoa Martínez-Pizarro , Eva Richard , Lourdes R Desviat , Johannes Häberle , Daan M F van Aalten , Nicola Brunetti-Pierri

Exploiting O-GlcNAc transferase promiscuity to dissect site-specific O-GlcNAcylation.

Glycobiology

Avec: Conor W Mitchell , Sergio Galan Bartual , Andrew T Ferenbach , Carsten Scavenius , Daan M F van Aalten

Genetic recoding to dissect the roles of site-specific protein O-GlcNAcylation.

Nature structural & molecular biology

Avec: Andrii Gorelik , Sergio Galan Bartual , Vladimir S Borodkin , Joby Varghese , Andrew T Ferenbach , Daan M F van Aalten

A missense mutation in the catalytic domain of O-GlcNAc transferase links perturbations in protein O-GlcNAcylation to X-linked intellectual disability.

FEBS letters

Avec: Veronica M Pravata , Mehmet Gundogdu , Sergio G Bartual , Andrew T Ferenbach , Marios Stavridis , Katrin Õunap , Sander Pajusalu , Riina Žordania , Monica H Wojcik , Daan M F van Aalten

Genetic validation of Aspergillus fumigatus phosphoglucomutase as a viable therapeutic target in invasive aspergillosis.

The Journal of biological chemistry

Avec: Kaizhou Yan , Mathew Stanley , Bartosz Kowalski , Olawale G Raimi , Andrew T Ferenbach , Pingzhen Wei , Wenxia Fang , Daan M F van Aalten

Catalytic deficiency of O-GlcNAc transferase leads to X-linked intellectual disability.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Veronica M Pravata , Villo Muha , Mehmet Gundogdu , Andrew T Ferenbach , Poonam S Kakade , Vasudha Vandadi , Ariane C Wilmes , Vladimir S Borodkin , Shelagh Joss , Marios P Stavridis , Daan M F van Aalten

A missense mutation in a patient with developmental delay affects the activity and structure of the hexosamine biosynthetic pathway enzyme AGX1.

FEBS letters

Avec: Xiping Chen , Olawale G Raimi , Andrew T Ferenbach , Daan M F van Aalten

An O-GlcNAc transferase pathogenic variant linked to intellectual disability affects pluripotent stem cell self-renewal.

Disease models & mechanisms

Avec: Michaela Omelková , Christina Dühring Fenger , Marta Murray , Trine Bjørg Hammer , Veronica M Pravata , Sergio Galan Bartual , Ignacy Czajewski , Allan Bayat , Andrew T Ferenbach , Marios P Stavridis , Daan M F van Aalten

Réseau de co-auteurs

Daan M F van Aalten 13 collaborations

Sergio Galan Bartual 4 collaborations

Veronica M Pravata 4 collaborations

Wenxia Fang 3 collaborations

Olawale G Raimi 3 collaborations

Marta Murray 2 collaborations

Villo Muha 2 collaborations

Ignacy Czajewski 2 collaborations

Vladimir S Borodkin 2 collaborations

Mehmet Gundogdu 2 collaborations

Marios P Stavridis 2 collaborations

Ana Belén Sanz 1 collaboration

Bin Wang 1 collaboration

Vladimír Farkaš 1 collaboration

Ramon Hurtado-Guerrero 1 collaboration

Javier Arroyo 1 collaboration

Lindsay Davidson 1 collaboration

Dirk Lefeber 1 collaboration

Yuanwei Zhang 1 collaboration

Deborah E A Lockhart 1 collaboration

Ling Lu 1 collaboration

Michaela Fenckova 1 collaboration

Daniel Mariappa 1 collaboration

Marica Catinozzi 1 collaboration

Laura E R Blok 1 collaboration

Erik Storkebaum 1 collaboration

Annette Schenck 1 collaboration

Florence Authier 1 collaboration

Nina Ondruskova 1 collaboration

Alison McNeilly 1 collaboration

Leandro R Soria 1 collaboration

Georgios Makris 1 collaboration

Alfonso M D'Alessio 1 collaboration

Angela De Angelis 1 collaboration

Iolanda Boffa 1 collaboration

Véronique Rüfenacht 1 collaboration

Sergio Attanasio 1 collaboration

Edoardo Nusco 1 collaboration

Paola Arena 1 collaboration

Debora Paris 1 collaboration

Paola Cuomo 1 collaboration

Andrea Motta 1 collaboration

Matthew Nitzahn 1 collaboration

Gerald S Lipshutz 1 collaboration

Ainhoa Martínez-Pizarro 1 collaboration

Eva Richard 1 collaboration

Lourdes R Desviat 1 collaboration

Johannes Häberle 1 collaboration

Nicola Brunetti-Pierri 1 collaboration

Conor W Mitchell 1 collaboration

Carsten Scavenius 1 collaboration

Andrii Gorelik 1 collaboration

Joby Varghese 1 collaboration

Sergio G Bartual 1 collaboration

Marios Stavridis 1 collaboration

Katrin Õunap 1 collaboration

Sander Pajusalu 1 collaboration

Riina Žordania 1 collaboration

Monica H Wojcik 1 collaboration

Kaizhou Yan 1 collaboration

Mathew Stanley 1 collaboration

Bartosz Kowalski 1 collaboration

Pingzhen Wei 1 collaboration

Poonam S Kakade 1 collaboration

Vasudha Vandadi 1 collaboration

Ariane C Wilmes 1 collaboration

Shelagh Joss 1 collaboration

Xiping Chen 1 collaboration

Michaela Omelková 1 collaboration

Christina Dühring Fenger 1 collaboration

Trine Bjørg Hammer 1 collaboration

Allan Bayat 1 collaboration