Avraham Shakked

Affiliations

Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.

Publications (8)

ERBB2 drives YAP activation and EMT-like processes during cardiac regeneration.

Nature cell biology

Avec: Alla Aharonov , Avraham Shakked , Kfir Baruch Umansky , Alon Savidor , Alexander Genzelinakh , David Kain , Daria Lendengolts , Or-Yam Revach , Yuka Morikawa , Jixin Dong , Yishai Levin , Benjamin Geiger , James F Martin , Eldad Tzahor

ERK1/2 inhibition promotes robust myotube growth via CaMKII activation resulting in myoblast-to-myotube fusion.

Developmental cell

Avec: Tamar Eigler , Giulia Zarfati , Emmanuel Amzallag , Sansrity Sinha , Nadav Segev , Yishaia Zabary , Assaf Zaritsky , Avraham Shakked , Kfir-Baruch Umansky , Eyal D Schejter , Douglas P Millay , Eldad Tzahor , Ori Avinoam

An enhancer-based gene-therapy strategy for spatiotemporal control of cargoes during tissue repair.

Cell stem cell

Avec: Ruorong Yan , Valentina Cigliola , Kelsey A Oonk , Zachary Petrover , Sophia DeLuca , David W Wolfson , Andrew Vekstein , Michelle A Mendiola , Garth Devlin , Muath Bishawi , Matthew P Gemberling , Tanvi Sinha , Michelle A Sargent , Allen J York , Avraham Shakked , Paige DeBenedittis , David C Wendell , Jianhong Ou , Junsu Kang , Joseph A Goldman , Gurpreet S Baht , Ravi Karra , Adam R Williams , Dawn E Bowles , Aravind Asokan , Eldad Tzahor , Charles A Gersbach , Jeffery D Molkentin , Nenad Bursac , Brian L Black , Kenneth D Poss

Single-cell analysis uncovers that metabolic reprogramming by ErbB2 signaling is essential for cardiomyocyte proliferation in the regenerating heart.

eLife

Avec: Hessel Honkoop , Dennis Em de Bakker , Alla Aharonov , Fabian Kruse , Avraham Shakked , Phong D Nguyen , Cecilia de Heus , Laurence Garric , Mauro J Muraro , Adam Shoffner , Federico Tessadori , Joshua Craiger Peterson , Wendy Noort , Alberto Bertozzi , Gilbert Weidinger , George Posthuma , Dominic Grün , Willem J van der Laarse , Judith Klumperman , Richard T Jaspers , Kenneth D Poss , Alexander van Oudenaarden , Eldad Tzahor , Jeroen Bakkers

Egr1 regulates regenerative senescence and cardiac repair.

Nature cardiovascular research

Avec: Lingling Zhang , Jacob Elkahal , Tianzhen Wang , Racheli Rimmer , Alexander Genzelinakh , Elad Bassat , Jingkui Wang , Dahlia Perez , David Kain , Daria Lendengolts , Roni Winkler , Hanna Bueno-Levy , Kfir Baruch Umansky , David Mishaly , Avraham Shakked , Shoval Miyara , Avital Sarusi-Portuguez , Naomi Goldfinger , Amir Prior , David Morgenstern , Yishai Levin , Yoseph Addadi , Baoguo Li , Varda Rotter , Uriel Katz , Elly M Tanaka , Valery Krizhanovsky , Rachel Sarig , Eldad Tzahor

Small-molecule inhibition of Lats kinases may promote Yap-dependent proliferation in postmitotic mammalian tissues.

Nature communications

Avec: Nathaniel Kastan , Ksenia Gnedeva , Theresa Alisch , Aleksandra A Petelski , David J Huggins , Jeanne Chiaravalli , Alla Aharanov , Avraham Shakked , Eldad Tzahor , Aaron Nagiel , Neil Segil , A J Hudspeth

Interplay between calcium and sarcomeres directs cardiomyocyte maturation during regeneration.

Science (New York, N.Y.)

Avec: Phong D Nguyen , Iris Gooijers , Giulia Campostrini , Arie O Verkerk , Hessel Honkoop , Mara Bouwman , Dennis E M de Bakker , Tim Koopmans , Aryan Vink , Gerda E M Lamers , Avraham Shakked , Jonas Mars , Aat A Mulder , Sonja Chocron , Kerstin Bartscherer , Eldad Tzahor , Christine L Mummery , Teun P de Boer , Milena Bellin , Jeroen Bakkers

Redifferentiated cardiomyocytes retain residual dedifferentiation signatures and are protected against ischemic injury.

Nature cardiovascular research

Avec: Avraham Shakked , Zachary Petrover , Alla Aharonov , Matteo Ghiringhelli , Kfir-Baruch Umansky , David Kain , Jacob Elkahal , Yalin Divinsky , Phong Dang Nguyen , Shoval Miyara , Gilgi Friedlander , Alon Savidor , Lingling Zhang , Dahlia E Perez , Rachel Sarig , Daria Lendengolts , Hanna Bueno-Levy , Nathaniel Kastan , Yishai Levin , Jeroen Bakkers , Lior Gepstein , Eldad Tzahor

Réseau de co-auteurs

Eldad Tzahor 8 collaborations

Alla Aharonov 3 collaborations

David Kain 3 collaborations

Daria Lendengolts 3 collaborations

Yishai Levin 3 collaborations

Jeroen Bakkers 3 collaborations

Kfir Baruch Umansky 2 collaborations

Alon Savidor 2 collaborations

Alexander Genzelinakh 2 collaborations

Kfir-Baruch Umansky 2 collaborations

Zachary Petrover 2 collaborations

Kenneth D Poss 2 collaborations

Hessel Honkoop 2 collaborations

Phong D Nguyen 2 collaborations

Lingling Zhang 2 collaborations

Jacob Elkahal 2 collaborations

Hanna Bueno-Levy 2 collaborations

Shoval Miyara 2 collaborations

Rachel Sarig 2 collaborations

Nathaniel Kastan 2 collaborations

Or-Yam Revach 1 collaboration

Yuka Morikawa 1 collaboration

Jixin Dong 1 collaboration

Benjamin Geiger 1 collaboration

James F Martin 1 collaboration

Tamar Eigler 1 collaboration

Giulia Zarfati 1 collaboration

Emmanuel Amzallag 1 collaboration

Sansrity Sinha 1 collaboration

Nadav Segev 1 collaboration

Yishaia Zabary 1 collaboration

Assaf Zaritsky 1 collaboration

Eyal D Schejter 1 collaboration

Douglas P Millay 1 collaboration

Ori Avinoam 1 collaboration

Ruorong Yan 1 collaboration

Valentina Cigliola 1 collaboration

Kelsey A Oonk 1 collaboration

Sophia DeLuca 1 collaboration

David W Wolfson 1 collaboration

Andrew Vekstein 1 collaboration

Michelle A Mendiola 1 collaboration

Garth Devlin 1 collaboration

Muath Bishawi 1 collaboration

Matthew P Gemberling 1 collaboration

Tanvi Sinha 1 collaboration

Michelle A Sargent 1 collaboration

Allen J York 1 collaboration

Paige DeBenedittis 1 collaboration

David C Wendell 1 collaboration

Jianhong Ou 1 collaboration

Junsu Kang 1 collaboration

Joseph A Goldman 1 collaboration

Gurpreet S Baht 1 collaboration

Ravi Karra 1 collaboration

Adam R Williams 1 collaboration

Dawn E Bowles 1 collaboration

Aravind Asokan 1 collaboration

Charles A Gersbach 1 collaboration

Jeffery D Molkentin 1 collaboration

Nenad Bursac 1 collaboration

Brian L Black 1 collaboration

Dennis Em de Bakker 1 collaboration

Fabian Kruse 1 collaboration

Cecilia de Heus 1 collaboration

Laurence Garric 1 collaboration

Mauro J Muraro 1 collaboration

Adam Shoffner 1 collaboration

Federico Tessadori 1 collaboration

Joshua Craiger Peterson 1 collaboration

Wendy Noort 1 collaboration

Alberto Bertozzi 1 collaboration

Gilbert Weidinger 1 collaboration

George Posthuma 1 collaboration

Dominic Grün 1 collaboration

Willem J van der Laarse 1 collaboration

Judith Klumperman 1 collaboration

Richard T Jaspers 1 collaboration

Alexander van Oudenaarden 1 collaboration

Tianzhen Wang 1 collaboration

Racheli Rimmer 1 collaboration

Elad Bassat 1 collaboration

Jingkui Wang 1 collaboration

Dahlia Perez 1 collaboration

Roni Winkler 1 collaboration

David Mishaly 1 collaboration

Avital Sarusi-Portuguez 1 collaboration

Naomi Goldfinger 1 collaboration

Amir Prior 1 collaboration

David Morgenstern 1 collaboration

Yoseph Addadi 1 collaboration

Baoguo Li 1 collaboration

Varda Rotter 1 collaboration

Uriel Katz 1 collaboration

Elly M Tanaka 1 collaboration

Valery Krizhanovsky 1 collaboration

Ksenia Gnedeva 1 collaboration

Theresa Alisch 1 collaboration

Aleksandra A Petelski 1 collaboration

David J Huggins 1 collaboration

Jeanne Chiaravalli 1 collaboration

Alla Aharanov 1 collaboration

Aaron Nagiel 1 collaboration

Neil Segil 1 collaboration

A J Hudspeth 1 collaboration

Iris Gooijers 1 collaboration

Giulia Campostrini 1 collaboration

Arie O Verkerk 1 collaboration

Mara Bouwman 1 collaboration

Dennis E M de Bakker 1 collaboration

Tim Koopmans 1 collaboration

Aryan Vink 1 collaboration

Gerda E M Lamers 1 collaboration

Jonas Mars 1 collaboration

Aat A Mulder 1 collaboration

Sonja Chocron 1 collaboration

Kerstin Bartscherer 1 collaboration

Christine L Mummery 1 collaboration

Teun P de Boer 1 collaboration

Milena Bellin 1 collaboration

Matteo Ghiringhelli 1 collaboration

Yalin Divinsky 1 collaboration

Phong Dang Nguyen 1 collaboration

Gilgi Friedlander 1 collaboration

Dahlia E Perez 1 collaboration

Lior Gepstein 1 collaboration