Brian Gebelein

Affiliations

Division of Developmental Biology, Cincinnati Children's Hospital, Cincinnati, United States.
Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, United States.

ORCID: 0000-0001-9791-9061

Publications (16)

Enhancer architecture sensitizes cell specific responses to

eLife

Avec: Yi Kuang , Ohad Golan , Kristina Preusse , Brittany Cain , Collin J Christensen , Joseph Salomone , Ian Campbell , FearGod V Okwubido-Williams , Matthew R Hass , Zhenyu Yuan , Nathanel Eafergan , Kenneth H Moberg , Rhett A Kovall , Raphael Kopan , David Sprinzak , Brian Gebelein

Physical interactions between Gsx2 and Ascl1 balance progenitor expansion versus neurogenesis in the mouse lateral ganglionic eminence.

Development (Cambridge, England)

Avec: Kaushik Roychoudhury , Joseph Salomone , Shenyue Qin , Brittany Cain , Mike Adam , S Steven Potter , Masato Nakafuku , Brian Gebelein , Kenneth Campbell

A Comprehensive Structure-Function Study of Neurogenin3 Disease-Causing Alleles during Human Pancreas and Intestinal Organoid Development.

Developmental cell

Avec: Xinghao Zhang , Patrick S McGrath , Joseph Salomone , Mohamed Rahal , Heather A McCauley , Jamie Schweitzer , Rhett Kovall , Brian Gebelein , James M Wells

Prediction of cooperative homeodomain DNA binding sites from high-throughput-SELEX data.

Nucleic acids research

Avec: Brittany Cain , Jordan Webb , Zhenyu Yuan , David Cheung , Hee-Woong Lim , Rhett A Kovall , Matthew T Weirauch , Brian Gebelein

Gli3 utilizes Hand2 to synergistically regulate tissue-specific transcriptional networks.

eLife

Avec: Kelsey H Elliott , Xiaoting Chen , Joseph Salomone , Praneet Chaturvedi , Preston A Schultz , Sai K Balchand , Jeffrey D Servetas , Aimée Zuniga , Rolf Zeller , Brian Gebelein , Matthew T Weirauch , Kevin A Peterson , Samantha A Brugmann

The cis-regulatory logic underlying abdominal Hox-mediated repression versus activation of regulatory elements in Drosophila.

Developmental biology

Avec: Arya Zandvakili , Juli D Uhl , Ian Campbell , Joseph Salomone , Yuntao Charlie Song , Brian Gebelein

Cooperative Gsx2-DNA binding requires DNA bending and a novel Gsx2 homeodomain interface.

Nucleic acids research

Avec: Jordan A Webb , Edward Farrow , Brittany Cain , Zhenyu Yuan , Alexander E Yarawsky , Emma Schoch , Ellen K Gagliani , Andrew B Herr , Brian Gebelein , Rhett A Kovall

Mechanisms Underlying Hox-Mediated Transcriptional Outcomes.

Frontiers in cell and developmental biology

Avec: Brittany Cain , Brian Gebelein

Notch dimerization and gene dosage are important for normal heart development, intestinal stem cell maintenance, and splenic marginal zone B-cell homeostasis during mite infestation.

PLoS biology

Avec: Francis M Kobia , Kristina Preusse , Quanhui Dai , Nicholas Weaver , Matthew R Hass , Praneet Chaturvedi , Sarah J Stein , Warren S Pear , Zhenyu Yuan , Rhett A Kovall , Yi Kuang , Natanel Eafergen , David Sprinzak , Brian Gebelein , Eric W Brunskill , Raphael Kopan

Olig2 defines a subset of neural stem cells that produce specific olfactory bulb interneuron subtypes in the subventricular zone of adult mice.

Development (Cambridge, England)

Avec: Ángela Del Águila , Mike Adam , Kristy Ullom , Nicholas Shaw , Shenyue Qin , Jacqueline Ehrman , Diana Nardini , Joseph Salomone , Brian Gebelein , Q Richard Lu , Steven S Potter , Ronald Waclaw , Kenneth Campbell , Masato Nakafuku

A Drosophila Su(H) model of Adams-Oliver Syndrome reveals cofactor titration as a mechanism underlying developmental defects.

PLoS genetics

Avec: Ellen K Gagliani , Lisa M Gutzwiller , Yi Kuang , Yoshinobu Odaka , Phillipp Hoffmeister , Stefanie Hauff , Aleksandra Turkiewicz , Emily Harding-Theobald , Patrick J Dolph , Tilman Borggrefe , Franz Oswald , Brian Gebelein , Rhett A Kovall

A Novel Variant of ATP5MC3 Associated with Both Dystonia and Spastic Paraplegia.

Movement disorders : official journal of the Movement Disorder Society

Avec: Derek E Neilson , Michael Zech , Robert B Hufnagel , Jesse Slone , Xinjian Wang , Shelli Homan , Lisa M Gutzwiller , Elizabeth J Leslie , Nancy D Leslie , Jianfeng Xiao , Peter Hedera , Mark S LeDoux , Brian Gebelein , Friederike Wilbert , Matthias Eckenweiler , Juliane Winkelmann , Donald L Gilbert , Taosheng Huang

Conserved Gsx2/Ind homeodomain monomer versus homodimer DNA binding defines regulatory outcomes in flies and mice.

Genes & development

Avec: Joseph Salomone , Shenyue Qin , Temesgen D Fufa , Brittany Cain , Edward Farrow , Bin Guan , Robert B Hufnagel , Masato Nakafuku , Hee-Woong Lim , Kenneth Campbell , Brian Gebelein

Mechanisms of stearoyl CoA desaturase inhibitor sensitivity and acquired resistance in cancer.

Science advances

Avec: Nicole Oatman , Nupur Dasgupta , Priyanka Arora , Kwangmin Choi , Mruniya V Gawali , Nishtha Gupta , Sreeja Parameswaran , Joseph Salomone , Julie A Reisz , Sean Lawler , Frank Furnari , Cameron Brennan , Jianqiang Wu , Larry Sallans , Gary Gudelsky , Pankaj Desai , Brian Gebelein , Matthew T Weirauch , Angelo D'Alessandro , Kakajan Komurov , Biplab Dasgupta

Enhancers with cooperative Notch binding sites are more resistant to regulation by the Hairless co-repressor.

PLoS genetics

Avec: Yi Kuang , Anna Pyo , Natanel Eafergan , Brittany Cain , Lisa M Gutzwiller , Ofri Axelrod , Ellen K Gagliani , Matthew T Weirauch , Raphael Kopan , Rhett A Kovall , David Sprinzak , Brian Gebelein

Cooperative Gsx2-DNA Binding Requires DNA Bending and a Novel Gsx2 Homeodomain Interface.

bioRxiv : the preprint server for biology

Avec: Jordan A Webb , Edward Farrow , Brittany Cain , Zhenyu Yuan , Alexander E Yarawsky , Emma Schoch , Ellen K Gagliani , Andrew B Herr , Brian Gebelein , Rhett A Kovall

Réseau de co-auteurs

Brittany Cain 8 collaborations

Joseph Salomone 8 collaborations

Rhett A Kovall 7 collaborations

Zhenyu Yuan 5 collaborations

Yi Kuang 4 collaborations

Matthew T Weirauch 4 collaborations

Ellen K Gagliani 4 collaborations

Raphael Kopan 3 collaborations

David Sprinzak 3 collaborations

Shenyue Qin 3 collaborations

Masato Nakafuku 3 collaborations

Kenneth Campbell 3 collaborations

Edward Farrow 3 collaborations

Lisa M Gutzwiller 3 collaborations

Kristina Preusse 2 collaborations

Ian Campbell 2 collaborations

Matthew R Hass 2 collaborations

Mike Adam 2 collaborations

Hee-Woong Lim 2 collaborations

Praneet Chaturvedi 2 collaborations

Jordan A Webb 2 collaborations

Alexander E Yarawsky 2 collaborations

Emma Schoch 2 collaborations

Andrew B Herr 2 collaborations

Robert B Hufnagel 2 collaborations

Ohad Golan 1 collaboration

Collin J Christensen 1 collaboration

FearGod V Okwubido-Williams 1 collaboration

Nathanel Eafergan 1 collaboration

Kenneth H Moberg 1 collaboration

Kaushik Roychoudhury 1 collaboration

S Steven Potter 1 collaboration

Xinghao Zhang 1 collaboration

Patrick S McGrath 1 collaboration

Mohamed Rahal 1 collaboration

Heather A McCauley 1 collaboration

Jamie Schweitzer 1 collaboration

Rhett Kovall 1 collaboration

James M Wells 1 collaboration

Jordan Webb 1 collaboration

David Cheung 1 collaboration

Kelsey H Elliott 1 collaboration

Xiaoting Chen 1 collaboration

Preston A Schultz 1 collaboration

Sai K Balchand 1 collaboration

Jeffrey D Servetas 1 collaboration

Aimée Zuniga 1 collaboration

Rolf Zeller 1 collaboration

Kevin A Peterson 1 collaboration

Samantha A Brugmann 1 collaboration

Arya Zandvakili 1 collaboration

Juli D Uhl 1 collaboration

Yuntao Charlie Song 1 collaboration

Francis M Kobia 1 collaboration

Quanhui Dai 1 collaboration

Nicholas Weaver 1 collaboration

Sarah J Stein 1 collaboration

Warren S Pear 1 collaboration

Natanel Eafergen 1 collaboration

Eric W Brunskill 1 collaboration

Ángela Del Águila 1 collaboration

Kristy Ullom 1 collaboration

Nicholas Shaw 1 collaboration

Jacqueline Ehrman 1 collaboration

Diana Nardini 1 collaboration

Q Richard Lu 1 collaboration

Steven S Potter 1 collaboration

Ronald Waclaw 1 collaboration

Yoshinobu Odaka 1 collaboration

Phillipp Hoffmeister 1 collaboration

Stefanie Hauff 1 collaboration

Aleksandra Turkiewicz 1 collaboration

Emily Harding-Theobald 1 collaboration

Patrick J Dolph 1 collaboration

Tilman Borggrefe 1 collaboration

Franz Oswald 1 collaboration

Derek E Neilson 1 collaboration

Michael Zech 1 collaboration

Jesse Slone 1 collaboration

Xinjian Wang 1 collaboration

Shelli Homan 1 collaboration

Elizabeth J Leslie 1 collaboration

Nancy D Leslie 1 collaboration

Jianfeng Xiao 1 collaboration

Peter Hedera 1 collaboration

Mark S LeDoux 1 collaboration

Friederike Wilbert 1 collaboration

Matthias Eckenweiler 1 collaboration

Juliane Winkelmann 1 collaboration

Donald L Gilbert 1 collaboration

Taosheng Huang 1 collaboration

Temesgen D Fufa 1 collaboration

Bin Guan 1 collaboration

Nicole Oatman 1 collaboration

Nupur Dasgupta 1 collaboration

Priyanka Arora 1 collaboration

Kwangmin Choi 1 collaboration

Mruniya V Gawali 1 collaboration

Nishtha Gupta 1 collaboration

Sreeja Parameswaran 1 collaboration

Julie A Reisz 1 collaboration

Sean Lawler 1 collaboration

Frank Furnari 1 collaboration

Cameron Brennan 1 collaboration

Jianqiang Wu 1 collaboration

Larry Sallans 1 collaboration

Gary Gudelsky 1 collaboration

Pankaj Desai 1 collaboration

Angelo D'Alessandro 1 collaboration

Kakajan Komurov 1 collaboration

Biplab Dasgupta 1 collaboration

Anna Pyo 1 collaboration

Natanel Eafergan 1 collaboration

Ofri Axelrod 1 collaboration