Christopher Geven

Affiliations

Department of Intensive Care Medicine, Radboud Center for Infectious Diseases (RCI), Radboud University Medical Center, Nijmegen, The Netherlands.

Publications (6)

A double-blind, placebo-controlled, randomised, multicentre, proof-of-concept and dose-finding phase II clinical trial to investigate the safety, tolerability and efficacy of adrecizumab in patients with septic shock and elevated adrenomedullin concentration (AdrenOSS-2).

BMJ open

Avec: Christopher Geven , Alice Blet , Matthijs Kox , Oliver Hartmann , Paul Scigalla , Jens Zimmermann , Gernot Marx , Pierre-François Laterre , Alexandre Mebazaa , Peter Pickkers

Bioactive Adrenomedullin, Organ Support Therapies, and Survival in the Critically Ill: Results from the French and European Outcome Registry in ICU Study.

Critical care medicine

Avec: Léa Lemasle , Alice Blet , Christopher Geven , Ményssa Cherifa , Benjamin Deniau , Alexa Hollinger , Marie-Céline Fournier , Xavier Monnet , Isabelle Rennuit , Michael Darmon , Pierre-François Laterre , Joachim Struck , Oliver Hartmann , Andreas Bergmann , Alexandre Mebazaa , Etienne Gayat

Experimental human endotoxemia as a model of systemic inflammation.

Biochimie

Avec: Dirk van Lier , Christopher Geven , Guus P Leijte , Peter Pickkers

Adrecizumab, a non-neutralizing anti-adrenomedullin antibody, improves haemodynamics and attenuates myocardial oxidative stress in septic rats.

Intensive care medicine experimental

Avec: Alice Blet , Benjamin Deniau , Christopher Geven , Malha Sadoune , Anaïs Caillard , Paul-Robert Kounde , Evelyne Polidano , Peter Pickkers , Jane-Lise Samuel , Alexandre Mebazaa

Preclinical safety evaluation of the adrenomedullin-binding antibody Adrecizumab in rodents, dogs and non-human primates.

Toxicology and applied pharmacology

Avec: Christopher Geven , Matthijs Kox , Alice Blet , Alexandre Mebazaa , Mathias Schroedter , Joachim Struck , Andreas Bergmann , Peter Pickkers

Adrenomedullin in heart failure: pathophysiology and therapeutic application.

European journal of heart failure

Avec: Adriaan A Voors , Daan Kremer , Christopher Geven , Jozine M Ter Maaten , Joachim Struck , Andreas Bergmann , Peter Pickkers , Marco Metra , Alexandre Mebazaa , Hans-Dirk Düngen , Javed Butler

Réseau de co-auteurs

Alexandre Mebazaa 5 collaborations

Peter Pickkers 5 collaborations

Alice Blet 4 collaborations

Joachim Struck 3 collaborations

Andreas Bergmann 3 collaborations

Matthijs Kox 2 collaborations

Oliver Hartmann 2 collaborations

Pierre-François Laterre 2 collaborations

Benjamin Deniau 2 collaborations

Paul Scigalla 1 collaboration

Jens Zimmermann 1 collaboration

Gernot Marx 1 collaboration

Léa Lemasle 1 collaboration

Ményssa Cherifa 1 collaboration

Alexa Hollinger 1 collaboration

Marie-Céline Fournier 1 collaboration

Xavier Monnet 1 collaboration

Isabelle Rennuit 1 collaboration

Michael Darmon 1 collaboration

Etienne Gayat 1 collaboration

Dirk van Lier 1 collaboration

Guus P Leijte 1 collaboration

Malha Sadoune 1 collaboration

Anaïs Caillard 1 collaboration

Paul-Robert Kounde 1 collaboration

Evelyne Polidano 1 collaboration

Jane-Lise Samuel 1 collaboration

Mathias Schroedter 1 collaboration

Adriaan A Voors 1 collaboration

Daan Kremer 1 collaboration

Jozine M Ter Maaten 1 collaboration

Marco Metra 1 collaboration

Hans-Dirk Düngen 1 collaboration

Javed Butler 1 collaboration