Colin M Fadzen

Affiliations

Department of Chemistry , Massachusetts Institute of Technology , Cambridge , Massachusetts 02139 , United States.

ORCID: 0000-0002-4139-9578

Publications (7)

Chimeras of Cell-Penetrating Peptides Demonstrate Synergistic Improvement in Antisense Efficacy.

Biochemistry

Avec: Colin M Fadzen , Rebecca L Holden , Justin M Wolfe , Zi-Ning Choo , Carly K Schissel , Monica Yao , Gunnar J Hanson , Bradley L Pentelute

Deep learning to design nuclear-targeting abiotic miniproteins.

Nature chemistry

Avec: Carly K Schissel , Somesh Mohapatra , Justin M Wolfe , Colin M Fadzen , Kamela Bellovoda , Chia-Ling Wu , Jenna A Wood , Annika B Malmberg , Andrei Loas , Rafael Gómez-Bombarelli , Bradley L Pentelute

Targeting glioblastoma using a novel peptide specific to a deglycosylated isoform of brevican.

Advanced therapeutics

Avec: Niklas von Spreckelsen , Colin M Fadzen , Nina Hartrampf , Yarah Ghotmi , Justin M Wolfe , Shipra Dubey , Bo Yeun Yang , Marie F Kijewski , Shuyan Wang , Charlotte Farquhar , Sonja Bergmann , Mykola Zdioruk , J Roscoe Wasserburg , Benjamin Scott , Emily Murrell , Fernanda C Bononi , Leonard G Luyt , Marcelo DiCarli , Martine L M Lamfers , Keith L Ligon , E Antonio Chiocca , Mariano S Viapiano , Bradley L Pentelute , Sean E Lawler , Choi-Fong Cho

CT and MRI features differentiating mucinous cystic neoplasms of the liver from pathologically simple cysts.

Clinical imaging

Avec: Mark A Anderson , Ranjodh S Dhami , Colin M Fadzen , George Molina , Martin S Taylor , Vikram Deshpande , Motaz Qadan , Onofrio A Catalano , Cristina R Ferrone , Amirkasra Mojtahed

A Tumor-Homing Peptide Platform Enhances Drug Solubility, Improves Blood-Brain Barrier Permeability and Targets Glioblastoma.

Cancers

Avec: Choi-Fong Cho , Charlotte E Farquhar , Colin M Fadzen , Benjamin Scott , Pei Zhuang , Niklas von Spreckelsen , Andrei Loas , Nina Hartrampf , Bradley L Pentelute , Sean E Lawler

A Platinum(IV) Prodrug-Perfluoroaryl Macrocyclic Peptide Conjugate Enhances Platinum Uptake in the Brain.

Journal of medicinal chemistry

Avec: Colin M Fadzen , Justin M Wolfe , Wen Zhou , Choi-Fong Cho , Niklas von Spreckelsen , Kathryn T Hutchinson , Yen-Chun Lee , E Antonio Chiocca , Sean E Lawler , Omer H Yilmaz , Stephen J Lippard , Bradley L Pentelute

A chemoselective strategy for late-stage functionalization of complex small molecules with polypeptides and proteins.

Nature chemistry

Avec: Daniel T Cohen , Chi Zhang , Colin M Fadzen , Alexander J Mijalis , Liana Hie , Kenneth D Johnson , Zachary Shriver , Obadiah Plante , Scott J Miller , Stephen L Buchwald , Bradley L Pentelute

Réseau de co-auteurs

Bradley L Pentelute 6 collaborations

Justin M Wolfe 4 collaborations

Niklas von Spreckelsen 3 collaborations

Sean E Lawler 3 collaborations

Choi-Fong Cho 3 collaborations

Carly K Schissel 2 collaborations

Andrei Loas 2 collaborations

Nina Hartrampf 2 collaborations

Benjamin Scott 2 collaborations

E Antonio Chiocca 2 collaborations

Rebecca L Holden 1 collaboration

Zi-Ning Choo 1 collaboration

Monica Yao 1 collaboration

Gunnar J Hanson 1 collaboration

Somesh Mohapatra 1 collaboration

Kamela Bellovoda 1 collaboration

Chia-Ling Wu 1 collaboration

Jenna A Wood 1 collaboration

Annika B Malmberg 1 collaboration

Rafael Gómez-Bombarelli 1 collaboration

Yarah Ghotmi 1 collaboration

Shipra Dubey 1 collaboration

Bo Yeun Yang 1 collaboration

Marie F Kijewski 1 collaboration

Shuyan Wang 1 collaboration

Charlotte Farquhar 1 collaboration

Sonja Bergmann 1 collaboration

Mykola Zdioruk 1 collaboration

J Roscoe Wasserburg 1 collaboration

Emily Murrell 1 collaboration

Fernanda C Bononi 1 collaboration

Leonard G Luyt 1 collaboration

Marcelo DiCarli 1 collaboration

Martine L M Lamfers 1 collaboration

Keith L Ligon 1 collaboration

Mariano S Viapiano 1 collaboration

Mark A Anderson 1 collaboration

Ranjodh S Dhami 1 collaboration

George Molina 1 collaboration

Martin S Taylor 1 collaboration

Vikram Deshpande 1 collaboration

Motaz Qadan 1 collaboration

Onofrio A Catalano 1 collaboration

Cristina R Ferrone 1 collaboration

Amirkasra Mojtahed 1 collaboration

Charlotte E Farquhar 1 collaboration

Pei Zhuang 1 collaboration

Wen Zhou 1 collaboration

Kathryn T Hutchinson 1 collaboration

Yen-Chun Lee 1 collaboration

Omer H Yilmaz 1 collaboration

Stephen J Lippard 1 collaboration

Daniel T Cohen 1 collaboration

Chi Zhang 1 collaboration

Alexander J Mijalis 1 collaboration

Liana Hie 1 collaboration

Kenneth D Johnson 1 collaboration

Zachary Shriver 1 collaboration

Obadiah Plante 1 collaboration

Scott J Miller 1 collaboration

Stephen L Buchwald 1 collaboration