Daniel Offen

Affiliations

a Laboratory of Neuroscience , Felsenstein Medical Research Center, Sackler Faculty of Medicine, Tel Aviv University , Tel Aviv , Israel.

Publications (28)

Voluntary exercise improves cognitive deficits in female dominant-negative DISC1 transgenic mouse model of neuropsychiatric disorders.

The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry

Avec: Hadar Segal-Gavish , Ran Barzilay , Ofri Rimoni , Daniel Offen

CrisPam: SNP-Derived PAM Analysis Tool for Allele-Specific Targeting of Genetic Variants Using CRISPR-Cas Systems.

Frontiers in genetics

Avec: Roy Rabinowitz , Shiri Almog , Roy Darnell , Daniel Offen

Efficacy of therapy by MK-28 PERK activation in the Huntington's disease R6/2 mouse model.

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics

Avec: Talya Shacham , Daniel Offen , Gerardo Z Lederkremer

Extracellular vesicles over adeno-associated viruses: Advantages and limitations as drug delivery platforms in precision medicine.

Advanced drug delivery reviews

Avec: Nataly Yom-Tov , Reut Guy , Daniel Offen

A novel specific PERK activator reduces toxicity and extends survival in Huntington's disease models.

Scientific reports

Avec: Javier Ganz , Talya Shacham , Maria Kramer , Marina Shenkman , Hagit Eiger , Nitai Weinberg , Ori Iancovici , Somnath Roy , Luba Simhaev , Benny Da'adoosh , Hamutal Engel , Nisim Perets , Yael Barhum , Moshe Portnoy , Daniel Offen , Gerardo Z Lederkremer

Prediction of synonymous corrections by the BE-FF computational tool expands the targeting scope of base editing.

Nucleic acids research

Avec: Roy Rabinowitz , Shiran Abadi , Shiri Almog , Daniel Offen

Exosomes derived from mesenchymal stem cells improved core symptoms of genetically modified mouse model of autism Shank3B.

Molecular autism

Avec: N Perets , O Oron , S Herman , E Elliott , D Offen

The Role of MAPK's Signaling in Mediating ApoE4-Driven Pathology In Vivo.

Current Alzheimer research

Avec: Shiran Salomon-Zimri , Amit Koren , Ariel Angel , Tali Ben-Zur , Daniel Offen , Daniel M Michaelson

Promising Opportunities for Treating Neurodegenerative Diseases with Mesenchymal Stem Cell-Derived Exosomes.

Biomolecules

Avec: Reut Guy , Daniel Offen

Mesenchymal Stem Cell-Derived Extracellular Vesicles as Proposed Therapy in a Rat Model of Cerebral Small Vessel Disease.

International journal of molecular sciences

Avec: Reut Guy , Shay Herman , Hadar Benyamini , Tali Ben-Zur , Hila Kobo , Metsada Pasmanik-Chor , Dafna Yaacobi , Eric Barel , Chana Yagil , Yoram Yagil , Daniel Offen

Liposome-based targeting of dopamine to the brain: a novel approach for the treatment of Parkinson's disease.

Molecular psychiatry

Avec: Meygal Kahana , Abraham Weizman , Martin Gabay , Yelena Loboda , Hadar Segal-Gavish , Avishai Gavish , Yael Barhum , Dani Offen , John Finberg , Nahum Allon , Moshe Gavish

Caspase-6 Knockout in the 5xFAD Model of Alzheimer's Disease Reveals Favorable Outcome on Memory and Neurological Hallmarks.

International journal of molecular sciences

Avec: Ariel Angel , Rotem Volkman , Tabitha Grace Royal , Daniel Offen

Human Muscle Progenitor Cells Overexpressing Neurotrophic Factors Improve Neuronal Regeneration in a Sciatic Nerve Injury Mouse Model.

Frontiers in neuroscience

Avec: Reut Guy , Frida Grynspan , Tali Ben-Zur , Avraham Panski , Ron Lamdan , Uri Danon , David Yaffe , Daniel Offen

Cannabidiol as a suggested candidate for treatment of autism spectrum disorder.

Progress in neuro-psychopharmacology & biological psychiatry

Avec: Shani Poleg , Pavel Golubchik , Daniel Offen , Abraham Weizman

Extracellular Vesicles Tracking and Quantification Using CT and Optical Imaging in Rats.

Bio-protocol

Avec: Shaowei Guo , Oshra Betzer , Nisim Perets , Shira Landau , Daniel Offen , Rachela Popovtzer , Shulamit Levenberg

Single-Base Resolution: Increasing the Specificity of the CRISPR-Cas System in Gene Editing.

Molecular therapy : the journal of the American Society of Gene Therapy

Avec: Roy Rabinowitz , Daniel Offen

A Novel Rodent Model of Hypertensive Cerebral Small Vessel Disease with White Matter Hyperintensities and Peripheral Oxidative Stress.

International journal of molecular sciences

Avec: Reut Guy , Rotem Volkman , Ella Wilczynski , Chana Yagil , Yoram Yagil , Michael Findler , Eitan Auriel , Uri Nevo , Daniel Offen

Mesenchymal stem cells derived extracellular vesicles improve behavioral and biochemical deficits in a phencyclidine model of schizophrenia.

Translational psychiatry

Avec: Hadas Tsivion-Visbord , Nisim Perets , Tamar Sofer , Lior Bikovski , Yona Goldshmit , Angela Ruban , Daniel Offen

Golden Exosomes Selectively Target Brain Pathologies in Neurodegenerative and Neurodevelopmental Disorders.

Nano letters

Avec: Nisim Perets , Oshra Betzer , Ronit Shapira , Shmuel Brenstein , Ariel Angel , Tamar Sadan , Uri Ashery , Rachela Popovtzer , Daniel Offen

Myeloperoxidase Deficiency Inhibits Cognitive Decline in the 5XFAD Mouse Model of Alzheimer's Disease.

Frontiers in neuroscience

Avec: Rotem Volkman , Tali Ben-Zur , Anat Kahana , Ben Zion Garty , Daniel Offen

Intranasal Delivery of Mesenchymal Stem Cell Derived Exosomes Loaded with Phosphatase and Tensin Homolog siRNA Repairs Complete Spinal Cord Injury.

ACS nano

Avec: Shaowei Guo , Nisim Perets , Oshra Betzer , Shahar Ben-Shaul , Anton Sheinin , Izhak Michaelevski , Rachela Popovtzer , Daniel Offen , Shulamit Levenberg

Computational normal mode analysis accurately replicates the activity and specificity profiles of CRISPR-Cas9 and high-fidelity variants.

Computational and structural biotechnology journal

Avec: Oded Shor , Roy Rabinowitz , Daniel Offen , Felix Benninger

Intranasal delivery of mesenchymal stem cells-derived extracellular vesicles for the treatment of neurological diseases.

Stem cells (Dayton, Ohio)

Avec: Shay Herman , Idan Fishel , Daniel Offen

Increased RNA editing in maternal immune activation model of neurodevelopmental disease.

Nature communications

Avec: Hadas Tsivion-Visbord , Eli Kopel , Ariel Feiglin , Tamar Sofer , Ran Barzilay , Tali Ben-Zur , Orly Yaron , Daniel Offen , Erez Y Levanon

ND-13, a DJ-1-Derived Peptide, Attenuates the Renal Expression of Fibrotic and Inflammatory Markers Associated with Unilateral Ureter Obstruction.

International journal of molecular sciences

Avec: Carmen De Miguel , Abigayle C Kraus , Mitchell A Saludes , Prasad Konkalmatt , Almudena Ruiz Domínguez , Laureano D Asico , Patricia S Latham , Daniel Offen , Pedro A Jose , Santiago Cuevas

Genes to treat excitotoxicity ameliorate the symptoms of the disease in mice models of multiple system atrophy.

Journal of neural transmission (Vienna, Austria : 1996)

Avec: Micaela Johanna Glat , Nadia Stefanova , Gregor Karl Wenning , Daniel Offen

Behavioral aspects and neurobiological properties underlying medical cannabis treatment in Shank3 mouse model of autism spectrum disorder.

Translational psychiatry

Avec: Shani Poleg , Emad Kourieh , Angela Ruban , Guy Shapira , Noam Shomron , Boaz Barak , Daniel Offen

CSF-derived extracellular vesicles from patients with Parkinson's disease induce symptoms and pathology.

Brain : a journal of neurology

Avec: Shay Herman , Ruth Djaldetti , Brit Mollenhauer , Daniel Offen

Réseau de co-auteurs

Reut Guy 5 collaborations

Nisim Perets 5 collaborations

Tali Ben-Zur 5 collaborations

Roy Rabinowitz 4 collaborations

Ariel Angel 3 collaborations

Shay Herman 3 collaborations

Rotem Volkman 3 collaborations

Oshra Betzer 3 collaborations

Rachela Popovtzer 3 collaborations

Hadar Segal-Gavish 2 collaborations

Ran Barzilay 2 collaborations

Shiri Almog 2 collaborations

Talya Shacham 2 collaborations

Gerardo Z Lederkremer 2 collaborations

Yael Barhum 2 collaborations

Chana Yagil 2 collaborations

Yoram Yagil 2 collaborations

Abraham Weizman 2 collaborations

Shani Poleg 2 collaborations

Shaowei Guo 2 collaborations

Shulamit Levenberg 2 collaborations

Hadas Tsivion-Visbord 2 collaborations

Tamar Sofer 2 collaborations

Angela Ruban 2 collaborations

Ofri Rimoni 1 collaboration

Roy Darnell 1 collaboration

Nataly Yom-Tov 1 collaboration

Javier Ganz 1 collaboration

Maria Kramer 1 collaboration

Marina Shenkman 1 collaboration

Hagit Eiger 1 collaboration

Nitai Weinberg 1 collaboration

Ori Iancovici 1 collaboration

Somnath Roy 1 collaboration

Luba Simhaev 1 collaboration

Benny Da'adoosh 1 collaboration

Hamutal Engel 1 collaboration

Moshe Portnoy 1 collaboration

Shiran Abadi 1 collaboration

N Perets 1 collaboration

O Oron 1 collaboration

S Herman 1 collaboration

E Elliott 1 collaboration

D Offen 1 collaboration

Shiran Salomon-Zimri 1 collaboration

Amit Koren 1 collaboration

Daniel M Michaelson 1 collaboration

Hadar Benyamini 1 collaboration

Hila Kobo 1 collaboration

Metsada Pasmanik-Chor 1 collaboration

Dafna Yaacobi 1 collaboration

Eric Barel 1 collaboration

Meygal Kahana 1 collaboration

Martin Gabay 1 collaboration

Yelena Loboda 1 collaboration

Avishai Gavish 1 collaboration

Dani Offen 1 collaboration

John Finberg 1 collaboration

Nahum Allon 1 collaboration

Moshe Gavish 1 collaboration

Tabitha Grace Royal 1 collaboration

Frida Grynspan 1 collaboration

Avraham Panski 1 collaboration

Ron Lamdan 1 collaboration

Uri Danon 1 collaboration

David Yaffe 1 collaboration

Pavel Golubchik 1 collaboration

Shira Landau 1 collaboration

Ella Wilczynski 1 collaboration

Michael Findler 1 collaboration

Eitan Auriel 1 collaboration

Uri Nevo 1 collaboration

Lior Bikovski 1 collaboration

Yona Goldshmit 1 collaboration

Ronit Shapira 1 collaboration

Shmuel Brenstein 1 collaboration

Tamar Sadan 1 collaboration

Uri Ashery 1 collaboration

Anat Kahana 1 collaboration

Ben Zion Garty 1 collaboration

Shahar Ben-Shaul 1 collaboration

Anton Sheinin 1 collaboration

Izhak Michaelevski 1 collaboration

Oded Shor 1 collaboration

Felix Benninger 1 collaboration

Idan Fishel 1 collaboration

Eli Kopel 1 collaboration

Ariel Feiglin 1 collaboration

Orly Yaron 1 collaboration

Erez Y Levanon 1 collaboration

Carmen De Miguel 1 collaboration

Abigayle C Kraus 1 collaboration

Mitchell A Saludes 1 collaboration

Prasad Konkalmatt 1 collaboration

Almudena Ruiz Domínguez 1 collaboration

Laureano D Asico 1 collaboration

Patricia S Latham 1 collaboration

Pedro A Jose 1 collaboration

Santiago Cuevas 1 collaboration

Micaela Johanna Glat 1 collaboration

Nadia Stefanova 1 collaboration

Gregor Karl Wenning 1 collaboration

Emad Kourieh 1 collaboration

Guy Shapira 1 collaboration

Noam Shomron 1 collaboration

Boaz Barak 1 collaboration

Ruth Djaldetti 1 collaboration

Brit Mollenhauer 1 collaboration